Stanley F. Fernandez MD, PhD

Stanley Fernandez

Stanley F. Fernandez

Associate Professor

Department of Medicine

Jacobs School of Medicine & Biomedical Sciences

Specialty/Research Focus

Cardiology; Cardiovascular Disease

Contact Information
Clinical and Translational Research Center
875 Ellicott Street
Suite 7030
Buffalo, New York 14203
Phone: 716-829-2663
Fax: 716-854-1840

Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD

Professional Summary:

My clinical practice focuses on all aspects of general cardiology. I work in areas from preventive cardiology, such as treatment of patients with resistant hypertension or high-risk complex dyslipidemia, to inpatient care of critically ill patients with acute coronary syndrome,congestive heart failure exacerbation or advanced valvular disorders.

I have particular expertise in noninvasive imaging techniques and use multimodality cardiac imaging to aid the diagnosis and treatment of patients with complex cardiovascular diseases. I am involved in the structural heart program at the Gates Vascular Institute (GVI) and am well-versed in ultrasound-based imaging modality. This includes interpretation of basic transthoracic and transesophageal echocardiograms as well as “interventional echocardiography,” which provides intraprocedural transesophageal imaging support for transcatheter aortic valve replacement (TAVR), MitraClip valve repair and left atrial appendage occluder deployment. I also perform and interpret 12-lead electrocardiograms, 24-hour Holter monitors, event monitors, 24-hour ambulatory blood pressure monitors, cardiac nuclear stress testing, stress echocardiograms and cardiac computed tomography (CT) angiography. My expertise in the range of cardiac imaging modalities allows me to provide guidance to medical practitioners from different specialties in the appropriate use and application of each modality.

My research focus spans both translational and clinical applications. Using a porcine model of ischemic heart disease, our team investigates cardiac autonomic regulation and remodeling, employing in-vitro protein analysis and whole animal PET imaging to identify sympathetic denervation and subsequent neuronal sprouting. This area of study has important implications in our understanding of the myocardial substrate that promotes vulnerability to electrical instability and sudden cardiac death. I am also conducting several clinical trials, including a Phase III PCSK9 inhibitor study to evaluate the clinical benefits of Evolucomab in high-risk populations (FOURIER trial, Amgen). I am also involved in a clinical trial using the repositionable Lotus valve system for transcatheter aortic valve replacement (REPRISE study, Boston Scientific).

As a faculty member in the Division of Cardiovascular Medicine, I teach medical students, internal medicine residents and cardiology fellows. I facilitate small group discussions for second-year medical students as part of the cardiovascular physiology curriculum, and I serve as a clinic preceptor for third-year medical students in the outpatient cardiology clinic. I also conduct inpatient rounds with residents and fellows. In addition, I teach cardiology fellows in the performance and proper interpretation of cardiac imaging modalities such as echocardiograms and stress testing.

Education and Training:

  • Fellowship, University at Buffalo (2010)
  • Residency, University at Buffalo (2007)
  • PhD, University at Buffalo (2004)
  • MD, University of the Philippines (1997)
  • BS, University of the Philippines (1992)


  • Medical Director, Non-Invasive Cardiology, Buffalo General Medical Center, Buffalo General Medical Center (2017-present)
  • Clinical Associate Professor of Medicine, Medicine, University at Buffalo (2016-present)
  • Research Assistant Professor, Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2010–2016)

Awards and Honors:

  • White Coat Teaching Award (2015)
  • William M and Stanley A. Bukowski Award, University at Buffalo (2007)
  • American Heart Association 4th Annual Hypertension Award (2002)
  • Mark Diamond Fund Research Award (2002)

Research Expertise:

  • Lipid management
  • Sudden cardiac death

Journal Articles:

See all (5 more)

Books and Book Chapters:

  • Fernandez SF, Canty JM, Fallavollita J. (2017) Atlas of Cardiac Innervation. In: PET imaging and quantitation of cardiac innervation. Spring International Publishing, 71-82.
  • Fernandez SF, Srikakarlapudi S and Izzo Jr JL. (2012) Blood pressure variability. In: Blood pressure variability. Academic Press, NY, 355-357.
  • Izzo JL Jr, Fernandez SF. (2004) Biochemical Assessment of Sympathoadrenal Activity. In: Biochemical assessment of sympathoadrenal activity. Academic Press, 234-238.

Professional Memberships:

  • Fellow, American College of Cardiology (2017–present)
  • Member, American Society of Preventive Cardiology (2012–present)
  • Member, American Society of Echocardiography (2010–present)
  • Member, American College of Physicians (2005–present)
  • Member, American Medical Association (2005–present)
  • Member, American Heart Association (2001–present)
  • Member, American Physiological Society (2000–present)


  • "Coronary Subclavian Steal Syndrome, A Rare Cause of Coronary Flow Heterogeneity Demonstrated on Vasodilator Stress Testing" American College of Cardiology Annual Scientific Session (2016)
  • "9th Annual Symposium: Coronary Artery Disease in Patients with PAD" ; ; Vascular Interventional Associates (2015)
  • "A Rare Case of Auto-resuscitation" ; American College of Physician (NY State Chapter) Annual Scientific Meeting (2015)
  • "Familial Hypercholesterolemia-A Frequently Missed Diagnosis" ; ; Mercy Hospital Grand Rounds (2015)
  • "Structural Heart Symposium: TEE for Watchman and MitraClip Device" (2015)
  • "Elevated High Sensitivity Troponin T (HsTnT) During Front-Line Therapy with Cyclophosphamide, Doxorubicin, Vincristine and Prednisone" American Society of Hematology (2014)
  • "Updates in Cardiac, Vascular and Neuroendovascular Medicine-Management of Hyperlipidemia" (2014)
  • "Addressing Acute Chest Pain Syndrome: Approaches to Prompt Diagnosis and Personalized Treatment of NSTE-ACS Patients" ; AlpenaRegional Medical Center (2013)
  • "Acute Coronary Syndrome: From the ED to the Coronary Care Unit to the Office" ; Hurley Medical Center-Mott Children's Place (2012)
  • "Management of Stable Ischemic Heart Disease: Reconciling the Treatment" ; TJ Sampson Community Hospital (2011)
  • "The Continuum of Stable Ischemic Heart Disease" ; Lourdes Medical Center
See all (1 more)

Service Activities:

  • American Journal of Physiology, Manuscript Reviewer
  • Cardiovascular Journal of Africa, Manuscript Reviewer
  • Experimental Neurology, Manuscript Reviewer
  • Journal of Cardiovascular Pharmacology and Therapeutics, Manuscript Reviewer

School News:

In the Media:

Clinical Specialties:

Clinical Offices:

Insurance Accepted:

Contact Information

Clinical and Translational Research Center
875 Ellicott Street
Suite 7030
Buffalo, New York 14203
Phone: 716-829-2663
Fax: 716-854-1840

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD