This course will provide students with hands-on experience in genomic techniques for target identification and validation, and computational techniques for the assessment of target “drugability” and structure-assisted drug discovery. Students are required to bring a notebook computer to class, as the course provides hands-on training using open-source software packages for the analysis of genomic data and molecular visualization. Before these two sections, students are introduced to the receptor and ion-channel basis of drug action, including receptor theory and genetic techniques for studying ion channel function.