Endocrinology and Diabetes

Our division cares for infants, children and adolescents affected by diabetes or hormonal disorders regarding the thyroid, growth, sexual development or puberty.

Our division is actively involved in the education of both residents and medical students. Our fellows play an integral role in educating these rotating trainees.

Our goal is to diagnose and treat hormonal disorders and diabetes in children from birth through young adulthood.

We specialize in the diagnosis and treatment of endocrine disorders including short stature, thyroid conditions, precocious and delayed puberty, adrenal disorders, bone diseases and disorders of sexual development. In addition, our Diabetes Center provides care to pediatric and young adults with both Type 1 and Type 2 diabetes.

Education and Training

Residents and Medical Students

Pediatric residents and medical students spend four-week electives in our various clinical settings. You will learn the fundamentals of the evaluation of patients with diabetes, short stature, tall stature, early or delayed puberty, disorders of sexual differentiation, thyroid disorders, pituitary disorders and abnormal weight gain.

If you choose this elective during Diabetes Camp, you will have the opportunity to spend either a day or a full week at the camp, which is sponsored by the American Diabetes Association. Residents and medical students will be assisting campers with diabetes management. As such, they will learn about blood sugar testing, insulin injections, insulin pump adjustments, insulin dose calculations and carbohydrate counting. This is a unique opportunity to learn how children with diabetes deal with everyday challenges including the effects of exercise or rainy days on blood sugars. As there will be more people with diabetes than without at camp, residents and medical students will learn more about diabetes than they can get from attending diabetes clinic.


We are involved in basic and clinical research focusing on insulin resistance/signaling and the treatment and prevention of overweight in the clinical setting. We also have several ongoing clinical studies involving patients with Type 1 and Type 2 diabetes. Our Diabetes Center is one of 83 sites across the United States participating in the Type 1 Diabetes Exchange, which is a unique platform for collaborative data collection and sharing. We have also been a participant of TrialNet, a federally-funded study for the screening and prevention of Type 1 diabetes. In addition to diabetes, we have participated in numerous trials investigating new drugs to promote growth or halt early puberty.

Opportunities are available for patients interested in participating in research studies led by our physicians with the assistance of experienced research personnel.

Areas of Research

Clinical Care

Our division is part of UBMD Pediatrics, a member of UBMD Physicians' Group, the medical practice plan for the University at Buffalo. Our pediatric endocrinologists see patients at all three pediatric outpatient centers located in Amherst, Buffalo and Hamburg. Diabetes is available at our Buffalo pediatric outpatient center. We also provide consultations to inpatients at Oishei Children's Hospital (OCH).

Diabetes Center

Our Diabetes Center provides services for the clinical evaluation and management of both pediatric and adolescent patients with Type 1 and Type 2 diabetes. We have a team of nine board certified pediatric endocrinologists-diabetologists, a pediatric nurse practitioner, three nurses, a registered dietitian and a part-time social worker. Together, we take care of more than 900 patients with diabetes in the Western New York community.

We have been recognized by the American Diabetes Association for the Education Recognition Program (ERP). OCH is the only pediatric hospital to have received the designation of “Diabetes Center of Excellence” for Type 2 diabetes from the New York State Department of Health with a grant awarded between 2006-2011, which was replaced by a grant awarded in 2011 for Obesity Prevention.

Additional Services

In addition to our focus on the prevention and treatment of diabetes, we provide comprehensive care to those affected by endocrine disorders. Members of our physician team participate in the Oishei Children’s Hospital neurofibromatosis and neuro-oncology multidisciplinary clinics. We coordinate care through our participation in Children’s Healthy Weigh of Buffalo, a comprehensive pediatric weight management center at OCH.

For the management of thyroid nodules and thyroid cancer, we have a multidisciplinary team including endocrinology, radiology, pediatric surgery and comprehensive cancer care through Roswell Park Comprehensive Cancer Center. We are also a New York State newborn screening referral center for congenital hypothyroidism, congenital adrenal hyperplasia and X-linked adrenoleukodystrophy.

Our group coordinates specialty endocrine testing and treatment including:

  • growth hormone stimulation testing
  • adrenal stimulation testing
  • water deprivation testing
  • assessments for precocious puberty
  • thyroid nodule fine needle aspiration biopsy
  • infusion treatments for bone disease

Clinical Trials

We are involved in many trials that bring the latest methods in management of diabetes and endocrine disorders to patients in Western New York. These include clinical trials investigating the use of novel medications in children, such as long acting growth hormone and agents to treat precocious puberty. We participate in various trials in youth with Type 1 diabetes, such as T1D Exchange, and Type 2 diabetes through the Pediatric Diabetes Consortium. Our patients have the opportunity to enroll in federally funded trials for screening and prevention of Type 1 diabetes via TrialNet.

Chief, Endocrinology and Diabetes

Mastrandrea, Lucy

Lucy Mastrandrea, MD, PhD

Associate Professor; Division Chief, Endocrinology/Diabetes

UBMD Pediatrics, Division of Endocrinology/Diabetes, 1001 Main Street Buffalo, NY 14203

Phone: (716) 323-0170; Fax: (716) 323-0297

Email: ldm@buffalo.edu


1001 Main Street
5th Floor
Buffalo, NY 14203

Phone: (716) 323-0170
Fax: (716) 323-0297

1001 Main Street
5th Floor
Buffalo, NY 14203

Phone: (716) 323-0160
Fax: (716) 323-0297