Kosman, PhD, studies how organisms acquire and metabolize iron
and copper, intrinsically toxic metals essential to cellular
respiration and oxygen transport. One of his goals is to develop
antifungal drugs to treat infections in humans.
Rajnarayanan, PhD, studies interactomes of the human estrogen
receptor, which is expressed in 70 percent of breast cancers. His
lab seeks to design molecules to improve the effects of
tamoxifen, a drug commonly prescribed to treat breast cancer.
Russo, MD, is internationally known for his work with strains
of E. coli that cause infections outside the intestine and result
in morbidity worldwide due to pneumonia, urinary tract infections
L. Dubocovich, PhD, works to elucidate melatonin’s
mechanism of action and role in modulating circadian rhythms. Her
lab develops novel molecules targeting melatonin receptors to treat
depression, sleep disorders and cardiovascular disease.
Dietz, PhD, investigates cellular changes by which drugs
“hijack” the central nervous system’s reward
circuitry, causing addiction. He studies how differences in
individuals’ molecular and behavioral plasticity mediate
susceptibility to drug abuse and relapse.