This course provides an overview of the methods, systems, tools and databases available for the storage, analysis and interpretation of the increasingly voluminous molecular genome and protein data. The course focuses on the use of these biological data for research in molecular biology, systems biology, genetics and genomics as well as for translating and integrating biological data with clinical health care data to help predict and prevent disease and help clinicians, patients and consumers understand and use this information to maintain health. The course also includes a brief review of current core terminology and concepts in molecular biology, systems biology, genetics and genomics for students without previous course work or training in biomedicine.