Building on BMI 506 as a prerequisite, this course provides students with hands-on experience with the methods, systems, tools and databases available for the storage, analysis and interpretation of the increasingly voluminous molecular genome and protein data.  The course focuses on exercises that make use of these biological big data for research in molecular biology, systems biology, genetics and genomics as well as for translating and integrating biological data with clinical health care data to help predict and prevent disease. Students will use BLAST (Basic Local Alignment Search Tool), Protein Structure Prediction Software and Galaxy to analyze genomic, epigenetic, gene expression and proteomic data.