The cited studies collectively focus on the impact of potentially inappropriate medications (PIMs) on older adults in the United States, particularly those aged 65 and older. The research highlights the association between PIMs and various health outcomes, including health-related quality of life, health care utilization, and costs.

Overall, these projects contribute to a growing body of evidence that highlights the detrimental effects of PIMs on older adults and the necessity for improved medication safety practices to enhance patient outcomes and reduce health care costs.

David Jacobs, PharmD, PhD (Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences)
Collin Clark, PharmD, BCPS, BCGP (Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences)
Robert Wahler, PharmD (Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences)
Ranjit Singh, MB BChir, MBA (Department of Family Medicine, Jacobs School of Medicine and Biomedical Sciences)

Agency for Healthcare Research and Quality (AHRQ) - [9/1/2023 - 6/30/2027]

Active

Characterizing Inappropriate Medication Use in Older Adults

• Clark CM, Guan J, Patel A, Stoll J, Wahler RG, Feuerstein S, Singh R, Jacobs D. Association between potentially inappropriate medications prescription and health-related quality of life among US older adults. J Am Geriatr Soc. 2024; 1-9. doi:10.1111/jgs.18957 (2022 Journal Impact Factor: 5.9)
• Shaver A, Clark CM, Hejna M, Feuerstein S, Wahler RG, Jacobs DM. Trends in falls risk increasing drugs (FRIDs) and rate of fatal falls in older adults, 1999-2017. Pharmacoepidemiol Drug Saf. 2021;30(8):1049-1056. https://doi.org/10.1002/pds.5201 PMID: 33534172. (2021 Journal Impact factor – 2.572)

Top Downloaded Article: *Among work published in an issue between 1 January 2021 – 31 December 2021.

• Clark CM, Shaver AL, Aurelio LA, Feuerstein SG, Wahler RG, Daly CJ, Jacobs DM. Potentially Inappropriate Medications are Associated with Increased Healthcare Utilization and Costs. J Am Geriatr Soc. 2020;68:2542-2550. https://doi.org/10.1111/jgs.16743

• Mak CMPS, Clark CM, Jacobs DM, Feuerstein SG, Singh R, Wahler RG. Prevalence of Potentially Inappropriate Medications Among Community-dwelling Patients with Dementia and Associated Healthcare Utilization.  JAGS. 2024;72(S1):S2. https://doi.org/10.1111/jgs.18893
• Guan JPS, Stoll JF, Jacobs D, Wahler RG, Singh R, Clark CM. Association between Potentially Inappropriate Medication Prescribing and Health-related Quality of Life among US Older Adults. JACCP: Journal of The American College of Clinical Pharmacy. 2021;4(12):1712. doi: https://doi.org/10.1002/jac5.1561
  • Winner of the ACCP Best Student Poster Award

• Shaver A, Clark CMF, Hejna MPS, Wahler RG, Jacobs DM. Trends in falls risk increasing drugs (FRIDs) and rate of fatal falls in older adults, 1999-2017.  J Am Pharm Assoc 2020;60(3):e80. doi: https://doi.org/10.1016/j.japh.2020.04.013.
  • Selected for the APhA-APRS ESAS Research's Top 10: Poster Session Forum

• Clark CMF, Aurelio LPS, Feuerstein S, Shaver A, Wahler RG, Daly C, Jacobs DM. Potentially inappropriate medication prescribing is associated with increased health care utilization and costs among older adults in the United States. J Am Coll Clin Pharm. 2020;3(1):269-70. doi: 10.1002/jac5.1204.
  • Best Poster Award Finalist, 40th American College of Clinical Pharmacy Annual Meeting

• Mak CMPS, Clark CM, Jacobs DM, Feuerstein SG, Singh R, Wahler RG. Prevalence of Potentially Inappropriate Medications Among Community-dwelling Patients with Dementia and Associated Healthcare Utilization.  JAGS. 2024;72(S1):S2. https://doi.org/10.1111/jgs.18893