Areas of Research

Mandip Panesar, MD.

Members of our division — including Mandip Panesar, MD — publish their research in journals such as the International Journal of Nephrology and Seminars in Dialysis.

Our faculty members and fellows are engaged in innovative translational, basic and clinical research in a variety of areas.

Our physician-scientists have made contributions to areas including:

  • the long-term renal impacts of chemotherapy agents in adult cancer patients
  • abdominal pain associated with IgA nephropathy
  • understanding the response of cells to conditions of hypo- and hyperosmolality
  • adverse events among renal transplant recipients receiving outpatient parenteral antimicrobial infusion therapy
  • prevalence, predictors and outcome of nephrology referral in stage 3 chronic kidney disease patients
  • the use and complications of medications used in transplant immunosuppression regimens

Wide Range of Research Interests

Members of our division have studied the influence of gender and race on renal transplant recipients’ metabolism of kidney medications. Results of this research have enabled us to identify the best treatment protocol for each of our patients.

Some of our faculty members concentrate on understanding mechanisms that underlie kidney disease, including the role of the complement system.

We have developed and studied animal models of:

  • systemic lupus erythematosus
  • diabetic nephropathy
  • glomerulonephritis
  • obstructive nephropathy
  • acute renal failure

Additionally, our research has suggested that transplantation is a viable, cost-effective option for incarcerated patients with end-stage renal disease, including those who have chronic hepatitis C infection.

Currently, our faculty members are pursuing research in these areas:

Jessy Alexander, PhD

  • Experimental renal inflammation
  • Monocytes in circulation and Macrophages in tissues
  • Mouse models of sterile inflammation and autoimmunity
  • Neuropsychiatric lupus
  • Nuances of complement and endothelial cells
  • Pathobiology of the complement system

Pradeep Arora, MD

  • Epidemiology of chronic kidney disease (CKD)

James Farry, MD, MS

  • Medication and toxin-induced acute kidney injury

James Lohr, MD

  • Epidemiology of acute kidney injury
  • Hypertension

Mandip Panesar, MD

  • Clinical informatics

Richard Quigg, MD

  • Clinical informatics
  • Experimental models of renal disease
  • Functional genomics
  • Pathobiology of the complement system

Rabi Yacoub, MD

  • Gut microbiota and renal diseases
  • Megalin and kidney diseases
  • Nephrin role in kidney development
  • Nephrin role in kidney disease
  • Uremic toxins and CVD/atherosclerosis