Shadman Sakib Khan
Shadman Sakib Khan works as a research technician in the laboratory of Elizabeth A. Wohlfert, PhD.
Shadman Sakib Khan earned a master’s degree in microbiology and immunology at UB and is now working as a research technician in the laboratory of Elizabeth A. Wohlfert, PhD, associate professor of microbiology and immunology.
What was it about the Jacobs School that stood out for you, as opposed to other schools?
UB is one of the leading and well-regarded research institutions in the state of New York. Moreover, the Jacobs School of Medicine and Biomedical Sciences offers cutting-edge research opportunities in the field of biomedical sciences, world-class faculty, and state-of-the-art facilities that align with my academic and career goals. Also, since my family lives in New York City, attending UB also gave me the opportunity to stay close to them.
What specifically attracted you to the microbiology master’s program?
Immunology is one of my favorite subjects, and the program’s focus on immunology as well as microbiology made it a no-brainer for me to join.
What is it like working in Dr. Wohlfert’s laboratory?
Dr. Wohlfert is an outstanding mentor, and working with her has significantly strengthened my critical thinking and research skills. Her guidance has been invaluable in helping me develop strong scientific writing and problem-solving skills. Moreover, her constant support during challenging times has meant a great deal to me.
What are the main areas of your research?
I study the parasite Toxoplasma gondii-host interactions within two types of skeletal muscle fibers — “Fast Twitch (Extensor digitorum longus) and Slow Twitch (Soleus)” during muscular toxoplasmosis.
What are the potential public health benefits of your research?
Toxoplasma gondii maintains long-term infections by developing tissue cysts, mainly in the brain and muscle. While its effects on the brain are well-researched due to neurological consequences, muscle tissue also acts as a significant site for persistent infection, influencing both health and disease transmission. There remain a lot of unsolved questions regarding skeletal muscle function during a chronic toxoplasma infection, and how the infection impacts fast and slow twitch muscles regarding overall muscle physiology and damage.
What are your career goals and how has your time at the Jacobs School prepared you?
My goal is to pursue a PhD and contribute to research (academia or industry) in immunology and infectious diseases. The Jacobs School has equipped me with a strong foundation in molecular biology, microbiology and immunology, along with hands-on research experience in experimental design and advanced lab techniques. Its collaborative environment has also strengthened my ability to work in diverse teams and communicate scientific research effectively.
