Conducts research focused on characterizing the contribution of copy number variations to the genetic architecture of Alzheimer’s disease to develop genetic biomarkers for risk stratification; explores olfactory identification deficit as a biomarker of the disease; and uses stem cell technology to study the disease mechanism.
Works to extend the boundaries of knowledge about neurological diseases and disorders through innovative neuroimaging research techniques and the application of bioinformatics resources.
Research encompasses neurobiology of children with autism spectrum disorders; concurrent seizure disorders; epileptiform abnormalities; etiology; screening and evaluation techniques.
Supports basic and clinical research related to the cause, prevention and treatment of myelin-related diseases, such as Krabbe and other leukodystrophies, multiple sclerosis and hereditary neuropathies.
Conducts research to understand mechanisms of disease progression, with a primary focus on the role of environmental factors and environmental-gene interactions. Also conducts clinical trials for new pharmacologic interventions.
Conducts clinical research and clinical trials in a wide variety of neuromuscular disorders with a focus on myasthenia gravis and peripheral neuropathy, including neuropathic pain.
Employs behavioral psychometrics to understand how cerebral disease affects personality, cognition and psychiatric stability. Develops widely adopted tests, notably memory tests, to determine areas of cognitive impairment in multiple sclerosis, cerebral injury and disease, and other conditions.