University at Buffalo (UB)
Publications related to current faculty and trainees from 2019-2025
Chang, Kordi, Hicar, Multisystem inflammatory syndrome in children/pediatric inflammatory multisystem syndrome: Clinical guidelines. In Rajkumar Rajendram, Victor R. Preedy, Vinood B. Patel and Colin R. Martin, editors: Management, Body Systems, and Case Studies in COVID-19, UK: Academic Press, 2024, pp. 221-233
Yu KOA, Campagnari AA, Luke-Marshall NR. Moraxella catarrhalis. In Feigin and Cherry's Textbook of Pediatric Infectious Diseases. 9th ed. Elsevier, in press, December 2024 publication date.
COVID-19 associated Multisystem Inflammatory Syndrome in Children (MIS-C) guidelines; revisiting the Western New York approach as the pandemic evolves. Hennon TR, Yu KOA, Penque MD, Abdul-Aziz R, Chang AC, McGreevy MB, Pastore JV, Prout AJ, Schaefer BA, Alibrahim OS, Gomez-Duarte OG, Hicar MD. Prog Pediatr Cardiol. 2021 Sep;62:101407. doi: 10.1016/j.ppedcard.2021.101407. Epub 2021 Jun 6. PMID: 34121829
COVID-19 associated Multisystem Inflammatory Syndrome in Children (MIS-C) guidelines; a Western New York approach. Hennon TR, Penque MD, Abdul-Aziz R, Alibrahim OS, McGreevy MB, Prout AJ, Schaefer BA, Ambrusko SJ, Pastore JV, Turkovich SJ, Gomez-Duarte OG, Hicar MD. Prog Pediatr Cardiol. 2020 May 23:101232. doi: 10.1016/j.ppedcard.2020.101232. PMID: 32837142
Inhalation Delivery of ß-glucan-chitosan-poly (lactic co-glycolic) acid Nanoparticles Enhance Alveolar Macrophage Rifampin Concentrations for the Treatment of Tuberculosis. Kutscher HL, Tamblin M, Karki S, Chaves L, Baird M, Parvin A, Smith E, Dube A, Zhang Z, Chakraborty S, Kenney PO, Reynolds JL. Advanced Therapeutics. 2024 July 2400057.
Identification of a mimotope of a complex gp41 Human Immunodeficiency Virus epitope related to a non-structural protein of Hepacivirus previously implicated in Kawasaki disease. Sojar H, Baron S, Hicar MD. bioRxiv [Preprint]. 2024 Jun 28:2024.06.26.600771. doi: 10.1101/2024.06.26.600771. PMID: 38979252 Preprint.
Seasonal Testing, Results, and Effect of the Pandemic on Coxsackievirus Serum Studies. Kordi R, Chang AJ^, Hicar MD Microorganisms. 2024 Feb 10;12(2):367. doi:10.3390/microorganisms12020367. PMID: 38399771
Low-volume enrichment method supports high throughput bacteriophage screening and isolation from wastewater. Kenney PO, Gómez-Duarte OG. PLoS One. 2024 Apr 16;19(4):e0298833. doi: 10.1371/journal.pone.0298833. eCollection 2024. PMID: 38626205 Free PMC article.
Retrospective analysis of vertical hepatitis C exposure and infection in children in Western New York. Dieye NL, Varol M, Zorich SC, Millen AE, Yu KO, Gomez-Duarte OG. 2023. BMC Gastroenterol 23(1): 242.
Presence of coronary aneurysms during Kawasaki Disease (KD) correlates with lower levels of autoantibodies to both full form and spliced variant of immune regulator Del-1. Prakash AV~, Welliver RR~, Mirmire S, Baron S, Hicar MD. Immunol Lett. 2023 Apr-May;256-257:34-41. doi: 10.1016/j.imlet.2023.03.007. Epub 2023 Apr 4. PMID: 37019289
Predicting Intravenous Immunoglobulin Resistance Among North American Children Hospitalized With Kawasaki Disease. Singh J, Chang A, Fusco NM, Hicar M. J Pediatr Pharmacol Ther. 2022;27(7):669-676. doi: 10.5863/1551-6776-27.7.669. Epub 2022 Sep 26. PMID: 36186240
Humoral cross-coronavirus responses against the S2 region in children with Kawasaki disease. Monteiro A~, Chang AJ, Welliver RR~, Baron S, Hicar MD. Virology. 2022 Oct;575:83-90. doi: 10.1016/j.virol.2022.08.010. Epub 2022 Sep 2. PMID: 36088793
Decreased Clinical Severity of Pediatric Acute COVID-19 and MIS-C and Increase of Incidental Cases during the Omicron Wave in Comparison to the Delta Wave. Kenney PO, Chang AJ, Krabill L~, Hicar MD. Viruses. 2023 Jan 7;15(1):180. doi: 10.3390/v15010180. PMID: 36680220 Free PMC article.
Highly mutated monoclonal antibody 3F2 targets a conformational and strain-restricted epitope in human immunodeficiency virus gp41 with significant antibody-dependent cell cytotoxicity. DeCotes D~, Baron S, Hoffman J, Garrett M, Sojar H, Hicar MD. Arch Virol. 2022 Nov;167(11):2193-2201. doi: 10.1007/s00705-022-05518-3. Epub 2022 Jul 24. PMID: 35871426 Free PMC article.
Robust humoral immune response after boosting in children with Multisystem Inflammatory Syndrome in Children. Chang AJ, Baron S, Hicar MD. IDCases. 2022 Jul 13;29:e01569. doi: 10.1016/j.idcr.2022.e01569. eCollection 2022. PMID: 35855943 Free PMC article.
Antibody dependent cell cytotoxicity is maintained by the unmutated common ancestor of 6F5, a Gp41 conformational epitope targeting antibody that utilizes heavy chain VH1-2. Wrotniak BH, Garrett M, Baron S, Sojar H, Shon A, Asiago-Reddy E, Yager J, Kalams S, Croix M~, Hicar MD. Vaccine. 2022 Jul 29;40(31):4174-4181. doi: 10.1016/j.vaccine.2022.05.083. Epub 2022 Jun 7. PMID: 35688727
Clonal expansion and markers of directed mutation of IGHV4-34 B cells in plasmablasts during Kawasaki disease. Chang AJ, Baron S, Hoffman J, Hicar MD. Mol Immunol. 2022 May;145:67-77. doi: 10.1016/j.molimm.2022.03.011. Epub 2022 Mar 15. PMID: 35303530 Free PMC article.
Serum Responses of Children With Kawasaki Disease Against Severe Acute Respiratory Syndrome Coronavirus 2 Proteins. Chang AJ, Croix M~, Kenney P, Baron S, Hicar MD. Pediatr Infect Dis J. 2020 Nov;39(11):e366-e367. doi: 10.1097/INF.0000000000002863. PMID: 33021596
Monoclonal Antibody 2C6 Targets a Cross-Clade Conformational Epitope in gp41 with Highly Active Antibody-Dependent Cell Cytotoxicity. Sojar H, Baron S, Sullivan JT, Garrett M, van Haaren MM, Hoffman J~, Overbaugh J, Doranz BJ, Hicar MD. J Virol. 2019 Aug 13;93(17):e00772-19. doi: 10.1128/JVI.00772-19. Print 2019 Sep 1. PMID: 31217246
Spatiotemporal Analysis and Epidemiology of Kawasaki Disease in Western New York: A 16-Year Review of Cases Presenting to a Single Tertiary Care Center. Chang A, Delmerico AM, Hicar MD. Pediatr Infect Dis J. 2019 Jun;38(6):582-588. doi: 10.1097/INF.0000000000002239. PMID: 30418354
Cardiac Biomarkers Aid in Differentiation of Kawasaki Disease from Multisystem Inflammatory Syndrome in Children Associated with COVID-19. Walton M, Raghuveer G, Harahsheh A, Portman MA, Lee S, Khoury M, Dahdah N, Fabi M, Dionne A, Harris TH, Choueiter N, Garrido-Garcia LM, Jain S, Dallaire F, Misra N, Hicar MD, Giglia TM, Truong DT, Tierney ESS, Thacker D, Nowlen TT, Szmuszkovicz JR, Norozi K, Orr WB, Farid P, Manlhiot C, McCrindle BW; International Kawasaki Disease Registry. Pediatr Cardiol. 2023 Dec 29:10.1007/s00246-023-03338-z. doi: 10.1007/s00246-023-03338-z. Online ahead of print. PMID: 38157048
COVID-19 Positive Versus Negative Complete Kawasaki Disease: A Study from the International Kawasaki Disease Registry. Jose J, Tierney ESS, Harahsheh AS, Dahdah N, Raghuveer G, Friedman KG, Khoury M, Hicar MD, Merves SA, Dallaire F, Farid P, Manlhiot C, Runeckles K, Misra N, Portman M, Ballweg JA, Lee S, Jain SS, Harris TH, Szmuszkovicz JR, Orr W, Larios G, McCrindle BW. Pediatr Cardiol. 2023 Aug;44(6):1373-1381. doi: 10.1007/s00246-023-03109-w. Epub 2023 Feb 14. PMID: 36786810 Free PMC article.
Association of anti-HSC70 autoantibodies with cutaneous ulceration and severe disease in juvenile dermatomyositis. Karasawa R, Yudoh K, Sato T, Tanaka M, Tamaki M, Sabbagh SE, O'Hanlon TP, Noroozi-Farhadi P, Targoff IN, Flegel WA, Mammen AL, Miller FW, Hicar MD, Rider LG, Jarvis JN. Rheumatology (Oxford). 2022 Jul 6;61(7):2969-2977. doi: 10.1093/rheumatology/keab846. PMID: 34791087 Free PMC article.
An immunoregulator nanomedicine approach for the treatment of tuberculosis. Yang L, Chaves L, Kutscher HL, Karki S, Tamblin M, Kenney P, Reynolds JL. Front Bioeng Biotechnol. 2023 May 25;11:1095926. doi: 10.3389/fbioe.2023.1095926. eCollection 2023. PMID: 37304141
Antibody induction in mice by liposome-displaced recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens. Biomed J. Zhou S, Yu KO, Mabrouk MT, Jahagirdar D, Huang WC, Guerra JA, He X, Ortega J, Poole ST, Hall ER, Gomez-Duarte OG, Maciel M, Lovell JF. 2023.
Identification of Anti-gp41 Monoclonal Antibodies That Effectively Target Cytotoxic Immunoconjugates to Cells Infected with Human Immunodeficiency Virus, Type 1. Klug G, Cole FM, Hicar MD, Watt C, Peters T, Pincus SH. Vaccines (Basel). 2023 Apr 12;11(4):829. doi: 10.3390/vaccines11040829. PMID: 37112741 Free PMC article.
Upregulation of type 1 conventional dendritic cells implicates antigen cross-presentation in multisystem inflammatory syndrome. Huang JJ, Gaines SB, Amezcua ML, Lubell TR, Dayan PS, Dale M, Boneparth AD, Hicar MD, Winchester R, Gorelik M. J Allergy Clin Immunol. 2022 Mar;149(3):912-922. doi: 10.1016/j.jaci.2021.10.015. Epub 2021 Oct 22. PMID: 34688775 Free PMC article.
Clinical characteristics, time course, treatment and outcomes of patients with immune checkpoint inhibitor-associated myocarditis. Puzanov I, Subramanian P, Yatsynovich YV, Jacobs DM, Chilbert MR, Sharma UC, Ito F, Feuerstein SG, Stefanovic F, Switzer B, Hicar MD, Curtis AB, Spangenthal EJ, Dy GK, Ernstoff MS, Vachhani P, Page BJ, Agrawal N, Khunger A, Kapoor A, Hattoum A, Schentag JJ. J Immunother Cancer. 2021 Jun;9(6):e002553. doi: 10.1136/jitc-2021-002553. PMID: 34162715
Rising pneumococcal antibiotic resistance in the post 13-valent pneumococcal conjugate vaccine era in pediatric isolates in a primary care setting. Kaur R, Pham M, Yu KO, Pichichero ME. 2021. Clin Infect Dis 72(5): 797-805.
An Engineered Biomimetic MPER Peptide Vaccine Induces Weakly HIV Neutralizing Antibodies in Mice. Shao S, Huang WC, Lin C, Hicar MD, LaBranche CC, Montefiori DC, Lovell JF. Ann Biomed Eng. 2020 Jul;48(7):1991-2001. doi: 10.1007/s10439-019-02398-8. Epub 2019 Dec 12. PMID: 31832930
How to and should we target EBV in MS? Eckert S, Jakimovski D, Zivadinov R, Hicar M, Weinstock-Guttman B. Expert Rev Clin Immunol. 2024 Jul;20(7):703-714. doi: 10.1080/1744666X.2024.2328739. Epub 2024 Mar 15. PMID: 38477887
Respiratory infections in patients with primary immunodeficiency. Lehman HK, Yu KO, Towe CT, Risma KA. 2022. J Allergy Clin Immunol: In Prac 10(3): 683-691.
Peptide-based Fusion Inhibitors for Preventing the Six-helix Bundle Formation of Class I Fusion Proteins: HIV and Beyond. Monteiro A~, Yu KOA, Hicar MD. Curr HIV Res. 2021;19(6):465-475. doi: 10.2174/1570162X19666210908115231. PMID: 34503415
Antibodies and Immunity During Kawasaki Disease. Hicar MD. Front Cardiovasc Med. 2020 May 28;7:94. doi: 10.3389/fcvm.2020.00094. eCollection 2020. PMID: 32671098. Review.
COVID-19 in Newborns and Infants-Low Risk of Severe Disease: Silver Lining or Dark Cloud? Rawat M, Chandrasekharan P, Hicar MD, Lakshminrusimha S. Am J Perinatol. 2020 Jun;37(8):845-849. doi: 10.1055/s-0040-1710512. Epub 2020 May 7. PMID: 32380565
B Cells and Antibodies in Kawasaki Disease. Lindquist ME, Hicar MD. Int J Mol Sci. 2019 Apr 13;20(8):1834. doi: 10.3390/ijms20081834. PMID: 31013925
The Role of a Spinning Top Urethra in the Development of Pyosalpinx in a Precoital Female. Andrews TJ, Hicar M, Islam S. Cureus. 2022 Jul 21;14(7):e27099. doi: 10.7759/cureus.27099. eCollection 2022 Jul. PMID: 36000094 Free PMC article.
Respiratory Failure in an Extremely Premature Neonate with COVID-19. Kumar VHS, Prasath A, Blanco C, Kenney PO, Ostwald CM, Meyer TS, Clementi CF, Maciejewski R, Wilby MT, Reynolds AM, Hpa NJ, Yu KO. 2021. Children 8: 477.
Pulmonary Involvement in Acute Rheumatic Fever: A Case Report and Literature Review. Kenney P, McMullin S, Abdul-Aziz R. Cureus. 2020 Mar 16;12(3):e7295. doi: 10.7759/cureus.7295.
Kikuchi-Fujimoto Disease: An important diagnostic consideration for cervical lymphadenitis in the pediatric population. Batton E, Alali M, Hageman JR, Parilla M, Yu KO. 2019. Pediatr Ann, 48(10): e406-e411.
Benson K, Kordi R, Bambach B, Yu KO. 2022. Severe respiratory syncytial virus infection and Haemophilus bacteremia as a presentation for aplastic anemia. J Clin Immunol, 42 (Suppl 1): S92-S93.
Yu KOA, Gomez-Duarte O. 2021. Lytic bacteriophage against an emergent biofilm-forming enteroinvasive Escherichia coli. J Ped Infect Dis Soc 10 (Suppl 1): S9.
Chang A, Goetz D, Hennon T, Kozielski R, Deutsch G, Yu KOA. 2021. Chronic Epstein-Barr virus infection and atypical sarcoidosis vs. granulocytic/lymphocytic interstitial lung disease in a child hemizygous for a pathogenic variant on SKIV2L. J Clin Immunol 41 (Suppl 1): S75.
Yu KOA, Mannix MK, Chang A. 2020. Multiple opportunistic infections in a hematopoietic cell transplant patient immunosuppressed with JAK and complement inhibitors. J Clin Immunol 40 (Suppl 1): S66-67.