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Jacobs School of Medicine and Biomedical Sciences

University at Buffalo (UB)

Jacobs School of Medicine and Biomedical Sciences

Department of Structural Biology

2/8/19 About Us
6/20/18 Education & Training
11/10/21 Faculty
6/18/18 Research & Facilities
6/19/25 News & Events

2/8/19 About Us
6/20/18 Education & Training
11/10/21 Faculty
6/18/18 Research & Facilities
6/19/25 News & Events

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Structural Biology >
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Research & Facilities

Areas of Research
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Departmental Facilities
- Protein Production and Crystallization
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Departmental Facilities

We offer trainees excellent opportunities for meaningful research in state-of-the-art facilities.

Protein Production and Crystallization
10/19/18

Recent Publications

- Pacesa M, Nickel L, Schellhaas C, Schmidt J, Pyatova E, Kissling L, Barendse P, Choudhury J, Kapoor S, Alcaraz-Serna A, Cho Y, Ghamary KH, Vinué L, Yachnin BJ, Wollacott AM, Buckley S, Westphal AH, Lindhoud S, Georgeon S, Goverde CA, Hatzopoulos GN, Gönczy P, Muller YD, Schwank G, Swarts DC, Vecchio AJ, Schneider BL, Ovchinnikov S, Correia BE. (2025) One-shot design of functional protein binders with BindCraft. Nature (Aug).
- Fisk MB, Barrera Ramirez J, Merrick CE, Wencewicz TA, Gulick AM. (2025) Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin. ACS chemical biology (Jun).

Recent Publications

- Pacesa M, Nickel L, Schellhaas C, Schmidt J, Pyatova E, Kissling L, Barendse P, Choudhury J, Kapoor S, Alcaraz-Serna A, Cho Y, Ghamary KH, Vinué L, Yachnin BJ, Wollacott AM, Buckley S, Westphal AH, Lindhoud S, Georgeon S, Goverde CA, Hatzopoulos GN, Gönczy P, Muller YD, Schwank G, Swarts DC, Vecchio AJ, Schneider BL, Ovchinnikov S, Correia BE. (2025) One-shot design of functional protein binders with BindCraft. Nature (Aug).
- Fisk MB, Barrera Ramirez J, Merrick CE, Wencewicz TA, Gulick AM. (2025) Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin. ACS chemical biology (Jun).

Research Funding

- Structure and assembly of membrane proteins at tight junctions. Alex Vecchio (Principal Investigator). NIH/NIGMS. $2,166,105. 9/1/2025-8/1/2030.
- Revolutionizing Protein Structure Determination with Advanced SWAXS Analysis. Thomas Grant (Principal Investigator). NIH NIGMS. $2,181,805. 8/1/2025-7/1/2030.
- Mid-scale RI-2: Compact X-ray Free-Electron Laser Project. Thomas Grant (Co-Investigator). National Science Foundation. $91,000,000. 3/1/2023-2/1/2028.

See all recent funding>

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Structural Biology >
Research & Facilities >
Departmental Facilities

Jacobs School of Medicine and Biomedical Sciences

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