We receive funding from a variety of sources that recognize the value of our high-impact research.
Mid-scale RI-2: Compact X-ray Free-Electron Laser Project. Thomas Grant (Co-Investigator). National Science Foundation. $91,000,000. 3/1/2023-2/1/2028.
Structure and assembly of membrane proteins at tight junctions. Alex Vecchio (Principal Investigator). NIH NIGMS. $1,802,852. 8/1/2020-7/1/2025.
Structural Studies of Nonribosomal Peptide Synthesis (R35GM136235). Andrew Gulick (Principal Investigator). NIH/NIGMS. 4/1/2020-3/1/2025.
High-resolution molecular recognition of ligands using solution X-ray scattering. Thomas Grant (Principal Investigator). National Institutes of Health. $1,333,637. 8/1/2019-7/1/2024.
Light-Induced Protein Quake of Visual Rhodopsin Investigated by Femtosecond Time-Resolved X-Ray Scattering. Thomas Grant (Co-Principal Investigator). National Science Foundation. $800,000. 8/1/2018-7/1/2024.
Exploring New Virulence Factors of the Oral Spirochete Treponema denticola. Michael Malkowski (Co-Principal Investigator). National Institutes of Health. 4/1/2019-3/1/2024.
Biology with X-ray free electron lasers. Thomas Grant (Co-Investigator). National Science Foundation. $44,563,810. 10/1/2013-9/1/2023.
Recent Publications
Erramilli S.K., Dominik P.K., Ogbu C.P., Kossiakoff A.A., and Vecchio A.J. (2023) Structural and biophysical insights into select targeting of claudin-4 composed tight junctions by a synthetic antibody. Nature Communications (Dec)
Goverde C.A., Pacesa M., Goldbach N., Dornfeld L.J., Georgeon S., Rosset S., Kapoor S., Choudhury J., Dauparas J., Schellhaas C., Kozlov S., Baker D., Vecchio A.J., Ovchinnikov S., and Correia B.E. (2023) Computational design of soluble analogues of integral membrane proteins. Nature (Dec)