Jack Reeves

Jack Reeves.

Jack Reeves

Jack Reeves

Thesis Title

Imaging the Role of Chronic Active Inflammation in Multiple Sclerosis Disease Progression

Research Publications Overview

Publications

  • Reeves, J.A., Bartnik, A., Mohebbi, M., Bergsland, N., Salman, F., Jakimovski, D., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2024). Longitudinal paramagnetic rim lesion evolution is related to clinical and radiological multiple sclerosis disease progression. Neurology. 
  • Reeves, J.A., Mohebbi, M., Wicks, T.R., Salman, F., Bartnik, A., Jakimovski, D., Bergsland, N., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2024). Paramagnetic rim lesions predict greater long-term relapse rates and clinical progression over 10 years. Multiple Sclerosis Journal. doi:10.1177/13524585241229956. 
  • Zivadinov, R., Tranquille, A., Reeves, J.A., Dwyer, M.G., Bergsland, N. (2024). Brain Atrophy assessment in multiple sclerosis: technical- and subject-related barriers for translation to real-world application in individual subjects. Expert Review of Neurotherapeutics. doi:10.1080/14737175.2024.2398484. 
  • Mohebbi, M., Reeves, J.A., Jakimovski, D., Bartnik, A., Bergsland, N., Salman, F., Schweser, F., Weinstock-Guttman, B., Zivadinov, R., Dwyer, M.G. (2024). Diffusion- and tractography-based characterization of tissue damage within and surrounding paramagnetic rim lesions in multiple sclerosis. American Journal of Neuroradiology. 
  • Wicks, T.R., Jakimovski, D., Reeves, J.A., Bergsland, N., Dwyer, M.G., Weinstock-Guttman, B., Zivadinov, R. (2024). Comorbid onset of cardiovascular diagnosis is associated with long-term confirmed disability progression in multiple sclerosis: a 15-year follow-up study. Journal of the Neurological Sciences. doi:10.1016/j.jns.2024.123156.
  • Reeves, J.A., Mohebbi, M., Zivadinov, R., Bergsland, N., Dwyer, M.G., Salman, F., Schweser, F., Jakimovski, D. (In press). Reliability of paramagnetic rim lesion classification on quantitative susceptibility mapping (QSM) in people with multiple sclerosis: single-site experience and systematic review. Multiple Sclerosis and Related Disorders. doi:10.1016/j.msard.2023.104968
  • Reeves, J.A.* and Weinstock*, Z., Zivadinov, R., Dwyer, M.G., Bergsland, N., Salman, F., Schweser, F., Weinstock-Guttman, B., Benedict, R.H.B., Jakimovski, D. (2023). Paramagnetic Rim Lesions are Associated with Greater Incidence of Relapse and Worse Cognitive Recovery Following Relapse. Multiple Sclerosis Journal. doi:10.1177/13524585231169466. *Contributed equally
  • Reeves, J.A., Bergsland, N., Dwyer, M.G., Wilding, G.E., Jakimovski, D., Salman, F., Sule, B., Meineke, N., Weinstock-Guttman, B., Zivadinov, R., Schweser, F. (2022). Susceptibility networks reveal independent patterns of brain iron abnormalities in multiple sclerosis. Neuroimage. https://doi.org/10.1016/j.neuroimage.2022.119503. 
  • Freedberg, M., Reeves, J.A., Fioriti, C., Murillo, J., Voss, J., Wassermann, E.M. (2022). A direct test of competitive versus cooperative episodic-procedural network dynamics in human memory. Cerebral Cortex, bhab512. https://doi.org/10.1093/cercor/bhab512. 
  • Freedberg, M., Reeves, J.A., Fioriti, C., Murillo, J., Wassermann, E.M. (2022). Reproducing the effect of hippocampal network-targeted transcranial magnetic stimulation on episodic memory. Behavioural Brain Research. Volume 419. https://doi.org/10.1016/j.bbr.2021.113707.
  • Freedberg, M., Cunningham, C.A., Fioriti, C., Murillo, J., Reeves, J.A., Taylor, P.A., Sarlls, J.E., Wassermann, E.M. (2021). The effect of parietal stimulation on hippocampal-cortical rsFC and episodic memory is associated with fractional anisotropy in multiple stimulation site pathways. Neuroimage. doi:10.1016/j.neuroimage.2021.118199.
  • Freedberg, M.* and Reeves, J.A.*, Hussain, S.J., Zaghloul, K.A., Wassermann, E.M. (2020). Identifying site- and stimulation-specific TMS-evoked EEG potentials using a quantitative cosine similarity metric. PLoS ONE 15(1): e0216185. doi:10.1371/journal.pone.0216185. *Contributed equally 
  • Freedberg, M.V., Reeves, J.A., Toader, A., Hermiller, M. Haubenberger, D., Cheung, Y.K., Voss, J., Wassermann, E.M. (2019). Optimizing hippocampal-cortical network modulation via repetitive transcranial magnetic stimulation: A dose-finding study using the continual reassessment method. Neuromodulation: Technology at the Neural Interface. doi:10.1111/ner.13052. 
  • Freedberg, M.V., Reeves, J.A., Toader, A., Hermiller, M., Voss, J., Wassermann, E.M. (2019). Enhancement of hippocampal network connectivity by parietal rTMS is reproducible: A replication study. eNeuro. doi:10.1523/ENEURO.0129-19.2019.
  • Hald, E.S., Steucke, K.E., Reeves, J.A., Win, Z., Alford, P.W. (2015). Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin Films. Journal of Visualized Experiments, (100). doi:10.3791/52971. 
  • Hald, E.S., Steucke, K.E., Reeves, J.A., Win, Z., Alford, P.W. (2014). Long-term Vascular Contractility Assay Using Genipin-modified Muscular Thin Films. Biofabrication, 6(4), 045005.

Professional/Educational Meetings/Abstracts

  • Reeves, J.A., Bartnik, A., Mohebbi, M., Bergsland, N., Jakimovski, D., Salman, F., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2024, Sep.). Paramagnetic rim lesion evolution is related to longitudinal clinical disease progression in people with multiple sclerosis. Oral presentation for the 149th Annual Meeting of the American Neurological Association, Orlando, FL 
  • Reeves, J.A., Bartnik, A., Mohebbi, M., Ramanathan, M., Bergsland, N., Jakimovski, D., Wilding, G.E., Salman, F., Schweser, F., Weinstock-Guttman, B., Hojnacki, D., Eckert, S., Dwyer, M.G., Zivadinov, R. (2024, Sep.). Sample size estimations for clinical trials using paramagnetic rim lesion rim disappearance or appearance as an endpoint. 40th Congress Of The European Committee For Treatment And Research In Multiple Sclerosis, Copenhagen, Denmark. 
  • Reeves, J.A., Jakimovski, D., Bergsland, N., Mohebbi, M., Salman, F., Schweser F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2024, April). Greater 5-year Gray Matter Atrophy Is Associated with Newly Arising Paramagnetic Rim Lesions, but Not Disappearing or Persisting Rim Lesions. Oral presentation for the American Academy of Neurology 2024 Annual Meeting, Denver, CO. 
  • Reeves, J.A., Jakimovski, D., Bergsland, B., Mohebbi, M., Salman, F., Schweser, F., Eckert, S., Hojnacki, D., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2024, Feb.). Disease modifying therapy use is associated with reduced paramagnetic rim lesion appearance, but not disappearance. Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2024, West Palm Beach, FL.
  • Reeves, J.A.*, Wicks, T.R.*, Mohebbi, M., Jakimovski, D., Bergsland, B., Salman, F., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2023, Oct.). Paramagnetic rim lesions predict greater relapse rates over 10-year follow-up. Oral presentation for 39th Congress Of The European Committee For Treatment And Research In Multiple Sclerosis, Milan, Italy. *Contributed equally 
  • Reeves, J.A.*, Wicks, T.R.*, Mohebbi, M., Jakimovski, D., Bergsland, B., Salman, F., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2023, Oct.). Baseline paramagnetic rim lesion presence does not predict greater disability progression over 10 years. 39th Congress Of The European Committee For Treatment And Research In Multiple Sclerosis, Milan, Italy. *Contributed equally 
  • Reeves, J.A., Jakimovski, D., Mohebbi, M., Bergsland, B., Salman, F., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2023, Oct.). Associations between paramagnetic rim lesions and proteomic levels. 39th Congress Of The European Committee For Treatment And Research In Multiple Sclerosis, Milan, Italy. 
  • Reeves, J.A., Salman, F., Dwyer, M.G., Bergsland, N., Muldoon, S., Zivadinov, R., Schweser, F. (2023, June). Short-term susceptibility correlations are sensitive to disrupted iron dynamics in multiple sclerosis. Oral presentation for The International Society for Magnetic Resonance in Medicine 2023 Annual Meeting, Toronto, Canada.
  • Jochmann, T.* and Reeves, J.A.*, Salman, F., Jakimovski, D., Hametner, S., Mohebbi, M., Bergsland, N., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R., Haueisen, J., Schweser, F. (2023, June). Nonsusceptibility frequency shift reveals subtypes of multiple sclerosis lesions and predicts 5-year disappearance of paramagnetic rim. The International Society for Magnetic Resonance in Medicine 2023 Annual Meeting, Toronto, Canada. *Contributed equally 
  • Reeves, J.A.* and Jochmann, T.*, Mohebbi, M., Jakimovski, D., Hametner, S., Salman, F., Bergsland, N., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R., Schweser, F. (2023, Feb). Novel MRI Technique Reveals Subtypes of Paramagnetic Rim Lesions and Predicts 5-year Rim Disappearance. Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2023, San Diego, CA. *Contributed equally 
  • Reeves, J.A.* and Mohebbi, M.*, Jakimovski, D., Salman, F., Bergsland, N., Schweser, F., Weinstock-Guttman, B. Dwyer, M.G., Zivadinov, R. (2023, Feb). Associations between different QSM lesion subtypes and brain atrophy in multiple sclerosis. Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2023, San Diego, CA. *Contributed equally
  • Mohebbi, M.* and Reeves, J.A.*, Jakimovski, D., Bergsland, N., Salman, F., Schweser, F., Weinstock-Guttman, B., Dwyer, M.G., Zivadinov, R. (2023, Feb). Paramagnetic rim lesion prevalence, clinical differences, and radiological associations using a standardized classification criteria. Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2023, San Diego, CA. *Contributed equally
  • Reeves, J.A., Bergsland, N., Jakimovski, D., Salman, F., Damm, J., Meineke, N., Dwyer, M.G., Zivadinov, R., Schweser, F. (2022, May). Discovery of two novel deep gray matter brain iron networks through an Independent Component Analysis of Quantitative Susceptibility Maps. The International Society for Magnetic Resonance in Medicine 2022 Annual Meeting, London, UK. 
  • Reeves, J.A., Bergsland, N., Jakimovski, D., Salman, F., Damm, J., Meineke, N., Dwyer, M., Zivadinov, R., Schweser, F. (2022, April). Two novel brain iron networks explain aging-related variation in deep gray matter. Accepted for poster presentation at the American Academy of Neurology 2022 Annual Meeting, Seattle, WA.
  • Freedberg, M., Reeves, J.A., Voss, J.L., Wassermann, E.M. (2019, October). Testing cooperation and competition between episodic and procedural memory systems using network-targeted rTMS. Poster for the Society for Neuroscience 49th Annual Meeting, Chicago, IL. 
  • Reeves, J.A., Hussain, S.J., Wassermann, E.M., Freedberg, M.V. (2018, May). Quantifying the stereotypy of TMS-evoked EEG potentials using a cosine similarity metric. Platform (oral) presentation for the 31st International Conference of Clinical Neurophysiology, Washington, DC. 
  • Reeves, J.A., Scott, J., Saad, Z., Inati, S.J., Inati, S.A. (2015, December). Identification of Epileptogenic Lesions Using a Template-Free Framework for Analysis of Multi-Contrast Anatomical MR Images. Poster for the American Epilepsy Society 69th Annual Meeting, Philadelphia, PA.