Megan Conrow-Graham
Thesis Title
Investigating the transcriptional repressors ADNP and POGZ reveals convergent mechanisms in neurodevelopmental disorders.
Publications
- M Conrow-Graham, J Williams, J Martin, P Zhong, B Rein, Q Cao, Z Yan (2022) A convergent mechanism of high-risk factors ADNP and POGZ in Neurodevelopmental Disorders. Brain.
- F Zhang, B Rein, P Zhong, Z Wang, M Conrow-Graham, T Shwani, Z Yan (2020) Amelioration of social deficits in adult Shank3 deficient mice via combined administration of histone deacetylase and demethylase inhibitors. Translational Psychiatry.
- T Tan, W Wang, T Liu, P Zhong, M Conrow-Graham, X Tian, Z Yan (2020) Neural circuits and activity dynamics underlying sex-specific effects of chronic social isolation stress. Cell Reports.
- B Rein, M Conrow-Graham, Q Cao, A Frazier, Z Yan (2021) Histone deacetylase 5 (HDAC5) mediated repression of Npas4 underlies GABA deficits and behavioral abnormalities in 16p11.2 duplication mice. In revision at Neuropharmacology.
- S Jee, AM Conn, M Conrow, N Herendeen (2020) Just Stand There and Listen. Clinical Pediatrics.
Professional/Educational Meetings/Abstracts
- M Conrow-Graham, JB Williams, D Holmes (2024). Review: Rates of Neurodevelopmental Disorders and Access to Services for Indigenous Peoples of the United States and Canada. Poster presentation at the American Association of Child and Adolescent Psychiatrists Annual Meeting, Seattle, Washington.
- M Conrow-Graham, J Williams, J Martin, P Zhong, Q Cao, B Rein, Z Yan (2022) Deficiency of the autism risk factors ADNP and POGZ induces neuroinflammation and impairs synaptic transmission. Poster presentation at Cell Symposium: The Biology of Neuropsychiatric Disorders, Sitges, Spain.
- M Conrow-Graham, J Williams, J Martin, P Zhong, Q Cao, B Rein, Z Yan (2022) Deficiency of two autism risk factors induces neuroinflammation and impairs synaptic transmission. Poster presentation at Celebration of Student Academic Excellence, University at Buffalo, Buffalo, NY.
- M Conrow-Graham, J Williams, J Martin, P Zhong, B Rein, Q Cao, Z Yan (2021) Neurodevelopmental disorder risk factors ADNP and POGZ affect convergent neuroinflammatory pathways. Poster presentation at Society for Neuroscience, Chicago, IL.
- M Conrow-Graham, J Martin, J Williams, P Zhong, B Rein, Z Yan (2021) Neurodevelopmental risk factors ADNP and POGZ demonstrate striking functional convergence. Oral presentation at Buffalo Neuroscience Research Day, virtual.
- M Conrow-Graham, J Martin, J Williams, P Zhong, B Rein, Z Yan (2021) Neurodevelopmental risk factors ADNP and POGZ affect convergent transcriptomic and synaptic functions. Poster presentation at Society for Neuroscience Global Connectome: A Virtual Event.
- F Zhang, B Rein, P Zhong, Z Wang, M Conrow-Graham, T Shwani, Z Yan (2020) Amelioration of social deficits in adult Shank3 deficient mice via combined administration of histone deacetylase and demethylase inhibitors. Translational Psychiatry.
- T Tan, W Wang, T Liu, P Zhong, M Conrow-Graham, X Tian, Z Yan (2020) Neural circuits and activity dynamics underlying sex-specific effects of chronic social isolation stress. Cell Reports.
- B Rein, M Conrow-Graham, Q Cao, A Frazier, Z Yan (2021) Histone deacetylase 5 (HDAC5) mediated repression of Npas4 underlies GABA deficits and behavioral abnormalities in 16p11.2 duplication mice. In revision at Neuropharmacology.
- M Conrow, Z Yan (2019) Targeted Knockdown of the High-Confidence Autism Risk Factor ADNP in Prefrontal Cortex Induces Cognitive Dysfunction. Poster presentation at University at Buffalo Neuroscience Research Day, Buffalo, NY; and at Tri-Institutional MD/PhD Conference, Buffalo, NY.
- M Conrow, Z Yan (2020) Cognitive and Transcriptional Disruptions Following ADNP Knockdown in Prefrontal Cortex. Oral presentation at Genetics, Genomics, and Bioinformatics Research Day, Buffalo, NY.
- “GAD67 and Parvalbumin Levels in Chandelier Cell Cartridge Boutons in Schizophrenia”, Center for Translational Mental Health Research Summer Fellowship Research Symposium, Pittsburgh, PA July 2015
- “A Pilot Study to Address Behavioral Concerns for Young Children in Primary Care”, Strong Children’s Research Center Poster Symposium, Rochester, NY August 2016