Cameron MacDonald

Cameron MacDonald.

Cameron MacDonald

Cameron MacDonald

Thesis Title

Determining the role of beta-adrenergic receptor signaling in tumor cell biology, and its impact on the anti-tumor immune response.

Research Publications Overview

Publications

  • Mohammadpour, H.; Sarow, J. L.; MacDonald, C. R.; Chen, G. L.; Qiu, J.; Sharma, U. C.; Cao, X.; Herr, M. M.; Hahn, T. E.; Blazar, B. R.; Repasky, E. A.; McCarthy, P. L. Β2-Adrenergic Receptor Activation on Donor Cells Ameliorates Acute GvHD. JCI Insight 2020, 5 (12).
  • MacDonald, C. R., Bucsek, M. J., Qiao, G., Chen, M., Evans, L., Greenberg, D. J., … Repasky, E. A. (2019). Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation. Radiation Research, 191(6), 585. 
  • Mohammadpour, H., MacDonald, C. R., Qiao, G., Chen, M., Dong, B., Hylander, B. L., … Repasky, E. A. (2019). β2 Adrenergic receptor-mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells. The Journal of Clinical Investigation. 
  • Bucsek, M. J., Giridharan, T., MacDonald, C. R., Hylander, B. L., & Repasky, E. A. (2018). An overview of the role of sympathetic regulation of immune responses in infectious disease and autoimmunity. International Journal of Hyperthermia, 34(2), 135–143. 
  • Bucsek, M. J., Qiao, G., MacDonald, C. R., Giridharan, T., Evans, L., Niedzwecki, B., … Repasky, E. A. (2017). β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy. Cancer Research, 77(20), 5639–5651. 
  • Qiao, G., Chen, M., Bucsek, M. J., Mohammadpour, H., MacDonald, C. R., Campbell, H. M., … Repasky, E. A. (2019). Adrenergic stress impairs CD8+T-cell activation and effector function, limiting antitumor immune responses: an in vivo analysis. The Journal of Immunology, 202(1 Supplement), 195.23-195.23. 
  • Bucsek, M. J., Qiao, G., Liu, H., Evans, L., MacDonald, C., Hylander, B., & Repasky, E. A. (2016). Adrenergic signaling mediates immune suppression induced by cool housing temperatures for laboratory mice. The Journal of Immunology, 196(1 Supplement), 72.8-72.8.

Professional/Educational Meetings/Abstracts

  • Cameron R. MacDonald, Hemn Mohammadpour, Guanxi Qiao, Minhui Chen, Bowen Dong, Bonnie L. Hylander, Philip L. McCarthy, Scott I. Abrams, Elizabeth A. Repasky “β2 adrenergic receptor–mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells” Translational Research Cancer Centers Consortium (TRCCC). Seven Springs, PA. 2020.
  • Cameron R. MacDonald, Mark J. Bucsek, Guanxi Qiao, Minhui Chen, Lauren Evans, Daniel J. Greenberg, Taylor P. Uccello, Nicholas G. Battaglia, Bonnie L. Hylander, Anurag K. Singh, Edith M. Lord, Scott A. Gerber, and Elizabeth A. Repasky. "Adrenergic receptor signaling regulates the response of tumors to ionizing radiation." Tri-Institutional Research Conference. Buffalo, NY. 2019. 
  • Cameron MacDonald, Mark Bucsek, Guanxi Qiao, Cameron MacDonald, Bonnie Hylander, Elizabeth Repasky. “Blockade of beta-adrenergic receptor signaling enhances anti-tumor immunity while increasing the sensitivity of tumor cells to radiation therapy” Translational Research Cancer Centers Consortium (TRCCC). Seven Springs, PA. 2017. 
  • Cameron MacDonald, Mark Bucsek, Guanxi Qiao, Cameron MacDonald, Bonnie Hylander, Elizabeth Repasky. “Blockade of beta-adrenergic receptor signaling enhances anti-tumor immunity while increasing the sensitivity of tumor cells to radiation therapy” Canisius College Ignation Scholarship Day. Buffalo, NY. 2017. 
  • Cameron MacDonald, Mark Bucsek, Guanxi Qiao, Cameron MacDonald, Bonnie Hylander, Elizabeth Repasky. "Blockade of β-adrenergic receptor signaling enhances anti-tumor immunity while increasing the sensitivity of tumor cells to radiation therapy" Society for Immunotherapy of Cancer (SITC). National Harbor, MD. 2016. 
  • Cameron MacDonald, Mark Bucsek, Guanxi Qiao, Elizabeth Repasky. “The role of β-adrenergic signaling in adenosine induced tumor growth, metastasis, and immune system evasion” Roswell Park Summer Research Experience Program Symposium. Buffalo, NY. 2016. 
  • Cameron MacDonald, Mark Bucsek, Guanxi Qiao, Elizabeth Repasky. “The role of β-adrenergic signaling in adenosine induced tumor growth, metastasis, and immune system evasion” Biomedical Research Day. Buffalo, NY. 2016. 
  • Cameron MacDonald, Mark Bucsek, Elizabeth Repasky, Joseph Spernyak. “MRI detection of brown adipose tissue transitioning to white adipose tissue under thermoneutral housing conditions” Roswell Park Summer Research Experience Program Symposium. Buffalo, NY. 2015. 
  • Cameron MacDonald, Mark Bucsek, Elizabeth Repasky, Joseph Spernyak. “MRI detection of brown adipose tissue transitioning to white adipose tissue under thermoneutral housing conditions” Biomedical Research Day Poster Presentation. Buffalo, NY. 2015.