Geovanny Perez MD

Geovanny Perez

Geovanny Perez
MD

Clinical Associate Professor and Division Chief, Pulmonology and Sleep Medicine

Department of Pediatrics

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Pediatric Pulmonology; Pediatrics

Contact Information
UBMD Pediatrics
Division of Pulmonology and Sleep Medicine
1001 Main Street
Buffalo, New York 14203
Phone: (716) 323-0110
Fax: (716) 323-0296
gperez9@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD


Education and Training:

  • MS, Clinical and Translational Research, George Washington University (2018)
  • Fellowship, Pediatric Pulmonology, George Washington University/Children’s National Medical Center (2014)
  • Residency, Pediatrics, Miami Children’s Hospital (2011)
  • Internship, Pediatrics, Miami Children's Hospital (2009)
  • Residency, Pediatric Oncology, Hospital SOLCA (2008)
  • MD, Medicine, Universidad Central del Ecuador, Summa Cum Laude (2004)

Employment:

  • Division Chief, Pulmonology and Sleep Medicine, UBMD Pediatrics (2020-present)
  • Medical Director, Pulmonology and Sleep Medicine, Oishei Children‘s Hospital (2020-present)
  • Attending Physician, Pulmonology and Sleep Medicine, Oishei Children‘s Hospital (2019-present)
  • Clinical Associate Professor, Pediatrics, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2019-present)
  • Assistant Professor, Genomics and Precision Medicine, George Washington University School of Medicine (2014–2019)
  • Assistant Professor, Pediatrics, George Washington University School of Medicine (2014–2019)
  • Adjunct Instructor, George Washington University School of Medicine and Health Sciences (2012–2014)
  • Rural Physician, Ecuador Health Ministry, Yaruqui Hospital (2004–2005)

Awards and Honors:

  • International Congress on Pediatric Pulmonology: Young Investigator Award (2016)
  • American Thoracic Society International Conference: Abstract Scholarship Award (2015)
  • American Federation of Medical Research Eastern Regional Meeting: Poster Award Moderator (2015)
  • 10th Annual Respiratory Disease Young Investigators’ Forum: Finalist/Certificate of Honor (2014)
  • International Congress on Pediatric Pulmonology: Young Investigator Award (2014)
  • American Thoracic Society International Conference: Minority Trainee Development Scholarship Award (2014)
  • American Federation of Medical Research Eastern Regional Meeting: Eastern Region Scholar Award (2014)
  • American Federation of Medical Research Eastern Regional Meeting: Henry Christian Award (2014)
  • American Federation of Medical Research Eastern Regional Meeting: Eastern Region Scholar Award (2013)
  • Miami Children's Hospital: Emergency Medicine Award (2009)
  • Universidad Central del Ecuador School of Medicine: 2nd Best Student of the Class of 2004 (2004)

Research Expertise:

  • Invasive and non-invasive ventilation: Management of children's with complex respiratory disorders that require invasive (CPAP/BPAP) or invasive ventilator support
  • Neuromuscular Disorders: Management of children with Neuromuscular Disorders.
  • Severe Bronchopulmonary Dysplasia (BPD): Inpatient and outpatient management of infants/children with severe chronic lung disease of prematurity.
  • Translational Research: My expertise are on the egulatory mechanisms of innate airway epithelial immunity in infants during viral respiratory infections using nasal and bronchial airway epithelial cells (AEC) isolated from young children. I also have experience working on clinical and preclinical phenotyping of viral respiratory infections and have participated in several research projects in the area. Using a translational approach in the VIRAL project I have identified that infants exhibit a Th2-biased airway immune responses against rhinovirus and and paramixoviruses such as RSV and human metapneumovirus. We have also found that the epithelial-derived cytokine thymic stromal lymphopoietin (TSLP) plays a key role in mediating Th2 responses during early life rhinovirus infection

Grants and Sponsored Research:

  • October 2018–December 2019
    Quantitative Proteomic Identification of Defective Innate Immune Secretory Responses to P. Aeruginosa in Cystic Fibrosis Bronchial Epithelium
    Gilead Sciencis, Inc.
    Role: Principal Investigator
    $88,142
  • January 2015–January 2017
    SRP-4045 and SRP-4053 in Duchene Muscular Dystrophy a 48-Week, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy and Safety of SRP-4045 and SRP-4053 in Patients with Duchenne Muscular Dystrophy
    Sarepta Therapeutics, Inc.
    Role: Co-Investigator
  • June 2014–November 2016
    A Phase 3 Efficacy and Safety Study of Ataluren (PTC124®) in Patients with Nonsense Mutation Cystic Fibrosis
    PTC Therapeutics, Inc.
    Role: Co-Investigator
  • December 2012–December 2014
    Microbiome Characterization in Pediatric Respiratory Disorders
    Parson’s Family Foundation Grant
    Role: Co-Investigator
    $20,000
  • October 2014–November 2014
    Flexible Bronchoscopy Atlas of Normal and Abnormal Pediatric Airways to be Used as Training Model
    Board of Visitors
    Role: Principal Investigator
    $4,000
  • June 2018
    Respiratory CPG Development
    Hunter‘s Hope Foundation
    Role: Principal Investigator
    $10,000
  • July 2017
    ASPIRO A Phase 1/2, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Preliminary Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) Patient
    Audentes Therapeutics
    Role: Contributor
  • October 2016
    A Prospective, Non Interventional Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects Aged 3 Years and Younger
    Audentes Therapeutics
    Role: Contributor

Journal Articles:

See all (35 more)

Books and Book Chapters:

  • Perez G, Koumbourlis A. (2015) In: "Pulmonary Function Test in the Intensive Care Unit". Nova Science Publishers

Professional Memberships:

  • American College of Chest Physicians (2017–present)
  • American Academy of Pediatrics Section on Pediatric Pulmonology: Fellow (2014–present)
  • American Academy of Pediatrics: Fellow (FAAP) (2011–present)
  • American Federation of Medical Research (2011–present)
  • American Thoracic Society (2011–present)
  • European Respiratory Society (2011–present)
  • Faculty of 1000 (2011–present)

Presentations:

  • "The New Guidelines for Asthma Management" Mini Grand Rounds; Oishei Children's Hospital (2021)
  • "Pulmonary Care in Patients with Congenital Muscular Dystrophy" KSSK CMD Chats: A Pulmonary Guide Web Series; Cure CMD (2021)
  • "Chronic Respiratory Failure" Pediatric Pulmonary Board Review Course; American College of Chest Physicians (2020)
  • "Restrictive Lung Disease" Pediatric Pulmonary Board Review Course; American College of Chest Physicians (2020)
  • "Clinical and Molecular Predictors of Recurrent Wheezing After the First Hospitalization Due to Viral Bronchiolitis" International Conference; American Thoracic Society (2019)
  • "Clinical and Non-Invasive Lung Imaging Predictors of Respiratory Hospitalizations During the First Year of Life in Infants Born Very Premature" International Conference; American Thoracic Society (2019)
  • "Don’t Take It for Granted! Improving Accurate Height Measurements for Pulmonary Function Testing in Non-Ambulatory Patients" International Conference; American Thoracic Society (2019)
  • "Dynamic PEEP Study: A Non-Invasive Diagnostic Exam to Assess for Effective PEEP in Fragile Children with Severe BPD" International Conference; American Thoracic Society (2019)
  • "Identification of Sub-Sets of Viral Bronchiolitis Based on Clinical Phenotyping, Quantitative Lung Imaging, Respiratory Outcomes and Airway Immune Responses" International Conference; American Thoracic Society (2019)
  • "Mechanisms of Hypoxemia and Hypoventilation in Neuromuscular Respiratory Failure" International Conference; American Thoracic Society; Management of Neuromuscular Respiratory Failure Syndromes: Nippv for Day, Night and the Soccer Field (2019)
  • "TSLP is the Predominant Innate Type 2 Cytokine Produced by the Human Infant Airway Epithelium" International Conference; American Thoracic Society (2019)
  • "Use of Quantitative Proteomic Analysis of CF and Non-CF Human Bronchial Epithelial (HBE) Cell Apical Secretome (AS) to Identify Changes in Innate Immunity of Lungs" International Conference; American Thoracic Society (2019)
  • "Young Children with Cystic Fibrosis Have Decreased Airway Microbial Diversity Compared to Healthy Controls of Similar Age" International Conference; American Thoracic Society (2019)
  • "Care of the Neuromuscular Patient and Care of the Patient with Severe BPD" Respiratorias Meeting; Sociedad Ecuatoriana de Tisiologia y Enfermedades (2019)
  • "Factors Associated with Extubation Failure in Pediatric Patients with Neuromuscular Disorders: A Retrospective Study" Annual Meeting; Pediatric Academic Societies (2019)
  • "Current Concepts on Prematurity" Pediatric Talk; HCAM Hospital (2018)
  • "Chronic Respiratory Failure (Noninvasive and Invasive Ventilation Tracheostomy)" Pulmonary Board Review; American College of Chest Physicians (2018)
  • "Restrictive Lung Disease" Pulmonary Board Review; American College of Chest Physicians (2018)
  • "'Trach Me Home': A Multidisciplinary Team Checklist to Reduce Readmissions and Emergency Department Visits Following Tracheostomy Placement in Ventilator Dependent Pediatric Patients" International Conference; American Thoracic Society (2018)
  • "Asthma is a Predictor of Continuous Positive Airway Pressure (CPAP) Initiation in Children with Severe Obstructive Sleep Apnea (OSA) Independent of Relevant Clinical and Demographic Variables" International Conference; American Thoracic Society (2018)
  • "Differing Changes within the Cystic Fibrosis Airway Microbiome" International Conference; American Thoracic Society (2018)
  • "Intrinsic Inflammatory and Innate Immune Gene Profiling in Pediatric Asthmatic Airway Epithelium" International Conference; American Thoracic Society (2018)
  • "Mixed Immune Response in Pediatric Severe Asthma Based on Bronchoalveolar Lavage" International Conference; American Thoracic Society (2018)
  • "Redefining Bronchiolitis: Respiratory Phenotyping of Viral Lower Respiratory Tract Infections Identifies Subsets with Distinct Acute Severity and Recurrence of Respiratory Illnesses During Early Life" International Conference; American Thoracic Society (2018)
  • "The Natural History of Patients with Congenital Muscular Dystrophy at Children’s National Health System: A Tertiary Medical Center Experience" International Conference; American Thoracic Society (2018)
  • "Transcriptomic Profiles of Conditional Reprogrammed Cells from Human Infant Airway Epithelial Cells Demonstrate Stability of Antiviral Immunity" International Conference; American Thoracic Society (2018)
  • "Functional Communication of Children with Spinal Muscular Atrophy Type 1" Clinical Conference; Muscular Dystrophy Association (2018)
  • "Implementation and Experience with Nusinersen (Spinraza) for Infants and Children with Spinal Muscular Atrophy (SMA) in Large Multidisciplinary Pediatric MDA Center" Clinical Conference; Muscular Dystrophy Association (2018)
  • "Using Spinraza to Treat Spinal Muscular Atrophy: Report of Practical Experience" Clinical Conference; Muscular Dystrophy Association (2018)
  • "Antibiotic Treatment Does Not Significantly Alter the CF Airway Microbiome" North American Cystic Fibrosis Conference; Cystic Fibrosis Foundation (2017)
  • "An Unusual Cause of Hypercarbia in Premature Twins" International Conference; American Thoracic Society (2017)
  • "Antiviral Signaling and Cytokine Responses in Nasal and Bronchial Airway Epithelial Cells from Preschool Children" International Conference; American Thoracic Society (2017)
  • "Application of Pharmacokinetics And Pharmacodynamics to Determine Dose Optimization Using Beta Lactams in Pediatric Cystic Fibrosis Population" International Conference; American Thoracic Society (2017)
  • "Choosing Ventilatory Support for Patients with Neuromuscular Disorders" International Conference; American Thoracic Society (2017)
  • "Clinical Definition of Respiratory Viral Infections in Young Children and Potential Bronchiolitis Misclassification" International Conference; American Thoracic Society (2017)
  • "Conditional Reprogramming of Pediatric Nasal Epithelial Cells: A New Model to Investigate Early Life Airway Immune Responses" International Conference; American Thoracic Society (2017)
  • "Distinguishing Characteristics of Severe Obstructive Sleep Apnea in Inner-City Children and Adolescents" International Conference; American Thoracic Society (2017)
  • "MRI Determination of Normal Volumes for the Upper Airway and Pharyngeal Lymphoid Tissue in Preterm and Term Infants" Annual Meeting; Society for Pediatric Radiology (2017)
  • "Peak Cough Flow Measurements in Children with Neuromuscular Disorders, 5 Years of Experience at Large Tertiary Children Hospital" International Conference; American Thoracic Society (2017)
  • "Marginal Shape Deep Learning: Applications to Pediatric Lung Field Segmentation" SPIE Medical Imaging; Society of Nuclear Medicine and Imaging (2017)
  • "Airway Molecular Phenotyping in Prematurity Identifies Intrinsic Secretory Signatures Linked to Th2 Inflammation and Airway Remodeling" International Congress on Pediatric Pulmonology; CIPP (2016)
  • "An Unusual Cause of Tachypnea and Hypoxemia in an Infant" International Conference; American Thoracic Society (2016)
  • "Automated Lung Segmentation And Longitudinal Air Trapping Quantification In Chronic Lung Disease Of Prematurity" International Conference; American Thoracic Society (2016)
  • "Different Sequencing Platforms Give Distinct Measures of Alpha Diversity of the Pulmonary Microbiome Detected in Cystic Fibrosis Sputum" Annual Meeting; Pediatric Academic Societies (2016)
  • "Physiological Biomarkers of Autonomic Dysfunction in Premature Infants Are Linked to High Risk of Hospital Readmission Due to Acute Life-Threatening Events (ALTE)" Annual Meeting; Pediatric Academic Societies (2016)
  • "Premature Infants Have an Intrinsic Airway Secretory Signature Characterized by Enhanced Production of Airway Remodeling Growth Factors" International Conference; American Thoracic Society (2016)
  • "Age-Related Effect of Viral-induced Wheezing in Severe Prematurity" International Conference; American Thoracic Society (2015)
  • "Characterization of Nasal Airway Microbiota During Acute Rhinovirus Infection in Full Term and in Premature Infants" International Conference; American Thoracic Society (2015)
  • "Clinical Phenotypic Characterization of Human Rhinovirus Infections in Severely Premature Children" International Conference; American Thoracic Society (2015)
  • "Cytokine Airway Responses to Acute Rhinovirus Infection and Respiratory Morbidity in Severe Premature Children" International Conference; American Thoracic Society (2015)
  • "Premature Infants have Impaired Airway Antiviral IFNγ Responses to Human Metapneumovirus Compared to Respiratory Syncytial Virus" International Conference; American Thoracic Society (2015)
  • "Premature Children Have Dysfunctional Airway Cytokine Responses to Rhinovirus and Respiratory Syncytial Virus" Annual Meeting; Pediatric Academic Societies (2015)
  • "Exosomal mir-155 Secretion During Rhinovirus Infection in Early Childhood" Annual Meeting; American Academy of Allergy, Asthma and Immunology (2015)
  • "Directional Immune Response and Polarity of Viral-Induced Thymic Stromal Lymphopoetin (TSLP) Secretion in Human Bronchial Epithelium" International Conference; American Thoracic Society (2014)
  • "Human Metapneumovirus is Associated with Severe Respiratory Disease in Premature Children" International Conference; American Thoracic Society (2014)
  • "Rhinovirus Infection in Early Childhood is Associated with Elevated Airway Thymic Stromal Lymphopoetin Levels and a Th2 Bias an Airway Immune Response" International Conference; American Thoracic Society (2014)
  • "REM Sleep-Related Vulnerability in Asthmatic Children is Independent of the Presence of OSA" SLEEP Meeting; Associated Professional Sleep Societies (2013)
  • "A Rare Case of Stridor, Wheezing and Pneumomediastinum" International Conference; American Thoracic Society; Pediatric Clinical Chest Round Cases (2013)
  • "Upper and Lower Airway Inflammation Modulate the Phenotypical Expression of OSA in Children" International Conference; American Thoracic Society (2013)
  • "High-Throughput Signal Processing of Polysomnography Identifies Airflow-Independent Respiratory Features of OSA in Adults" Eastern Regional Meeting; American Federation of Medical Research (2013)
  • "REM Sleep-Related Vulnerability in Asthmatic Children is Independent of the Presence of Obstructive Sleep Apnea (OSA)" Research Week; Children‘s National Medical Center (2013)
  • "Rhinovirus Infection is Associated with Increased Levels of Thymic Stromal Lymphopoietin (TSLP)" Eastern Regional Meeting; American Federation of Medical Research (2013)
  • "Upper and Lower Airway Inflammation Modulate the Phenotypical Expression of OSA in Children" Eastern Regional Meeting; American Federation of Medical Research (2013)
  • "Cystic Fibrosis Review for Parents" Cystic Fibrosis Symposium; Children’s National Medical Center/Hospital Carlos Andrade de Marin/Hospital Eugenio Espejo (2012)
  • "Complications of Nissen Fundoplication after Gastrostomy Tube Placement in CF Patients" North American Cystic Fibrosis Conference; Cystic Fibrosis Foundation; Pediatric Fellow Session (2011)
  • "Respiratory Care of Children with Neuromuscular Disease" I Symposium on Neuromuscular Disease in Children; HOMI Hospital de la Misericordia Foundation
See all (56 more)

Service Activities:

  • Lung Journal; Reviewer (2019–present)
  • Audentes Pharmaceuticals; Advisory Board (2018–present)
  • Journal of Pediatrics; Reviewer (2018–present)
  • Children's National Medical Center: Pediatric Surgery Verification Program Liaison (2017–2019)
  • Children's National Medical Center: Antimicrobial Subcommittee; Committee Member (2017–2019)
  • American Thoracic Society International Conference: Pediatric Asthma Mini Symposium; Co-Chair (2017)
  • Cure CMD: Pulmonary Guidelines Committee; Committee Member (2017)
  • Santhera Pharmaceuticals; Advisory Board (2017–present)
  • Hunter’s Hope Foundation: Pulmonary Guidelines for Patients with Leukodystrophies Committee Leader (2016–present)
  • Journal of Respiratory Medicine and Lung Disease Editorial Team Member (2016–present)
  • Metropolitan District of Columbia Thoracic Society; Board Member (2016–present)
  • Children's National Medical Center: Grand Rounds Improvement Committee; Committee Member (2015–2019)
  • Children's National Medical Center: Tracheostomy and Mechanical Ventilation Committee of Excellence; Committee Member (2015–2019)
  • Experimental Lung Research Journal; Reviewer (2015–present)
  • American Journal of Respiratory and Critical Care Medicine; Reviewer (2015–present)
  • Children's National Medical Center: Pediatric Pulmonology Fellowship Program Supervisor (2014–2019)
  • Children's National Medical Center: Pediatric Residency Program Supervisor (2014–2019)
  • Global Tracheostomy Consortium: Data Base Committee; Committee Member (2014–present)
  • American Thoracic Society: Pediatrics International Relations Working Group; Member (2014–present)
  • Pediatric Pulmonology; Reviewer (2014–present)
  • American Thoracic Society: Assembly on Pediatrics; Member (2013–present)

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Contact Information

UBMD Pediatrics
Division of Pulmonology and Sleep Medicine
1001 Main Street
Buffalo, New York 14203
Phone: (716) 323-0110
Fax: (716) 323-0296
gperez9@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD