UBMD Pediatrics Division of Pulmonology and Sleep Medicine 1001 Main Street Buffalo, New York 14203 Phone: (716) 323-0110 Fax: (716) 323-0296 gperez9@buffalo.edu
Gold Humanism Honor Society Richard Sarkin, MD—Medical Emeritus Faculty Chapter, Inductee (2022)
Pediatric Pulmonologist Top Doctors (2020)
International Congress on Pediatric Pulmonology: Young Investigator Award (2016)
American Thoracic Society International Conference: Abstract Scholarship Award (2015)
American Federation of Medical Research Eastern Regional Meeting: Poster Award Moderator (2015)
10th Annual Respiratory Disease Young Investigators’ Forum: Finalist/Certificate of Honor (2014)
International Congress on Pediatric Pulmonology: Young Investigator Award (2014)
American Thoracic Society International Conference: Minority Trainee Development Scholarship Award (2014)
American Federation of Medical Research Eastern Regional Meeting: Henry Christian Award (2014)
American Federation of Medical Research Eastern Regional Meeting: Eastern Region Scholar Award (2014)
American Federation of Medical Research Eastern Regional Meeting: Eastern Region Scholar Award (2013)
Miami Children's Hospital: Emergency Medicine Award (2009)
Magna Cum Laude (2004)
Research Expertise:
Airway epithelial immunity
Invasive and non-invasive ventilation: Management of children's with complex respiratory disorders that require invasive (CPAP/BPAP) or invasive ventilator support
Neuromuscular Disorders: Management of children with Neuromuscular Disorders.
Severe Bronchopulmonary Dysplasia (BPD): Inpatient and outpatient management of infants/children with severe chronic lung disease of prematurity.
Translational Research: My expertise are on the egulatory mechanisms of innate airway epithelial immunity in infants during viral respiratory infections using nasal and bronchial airway epithelial cells (AEC) isolated from young children. I also have experience working on clinical and preclinical phenotyping of viral respiratory infections and have participated in several research projects in the area. Using a translational approach in the VIRAL project I have identified that infants exhibit a Th2-biased airway immune responses against rhinovirus and and paramixoviruses such as RSV and human metapneumovirus. We have also found that the epithelial-derived cytokine thymic stromal lymphopoietin (TSLP) plays a key role in mediating Th2 responses during early life rhinovirus infection
UB 2020 Strategic Strengths:
Molecular Recognition in Biological Systems and Bioinformatics
Grants and Sponsored Research:
October 2018–December 2019 Quantitative Proteomic Identification of Defective Innate Immune Secretory Responses to P. Aeruginosa in Cystic Fibrosis Bronchial Epithelium Gilead Sciencis, Inc. Role: Principal Investigator $88,142
January 2015–January 2017 SRP-4045 and SRP-4053 in Duchene Muscular Dystrophy a 48-Week, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy and Safety of SRP-4045 and SRP-4053 in Patients with Duchenne Muscular Dystrophy Sarepta Therapeutics, Inc. Role: Co-Investigator
June 2014–November 2016 A Phase 3 Efficacy and Safety Study of Ataluren (PTC124®) in Patients with Nonsense Mutation Cystic Fibrosis PTC Therapeutics, Inc. Role: Co-Investigator
December 2012–December 2014 Microbiome Characterization in Pediatric Respiratory Disorders Parson’s Family Foundation Grant Role: Co-Investigator $20,000
October 2014–November 2014 Flexible Bronchoscopy Atlas of Normal and Abnormal Pediatric Airways to be Used as Training Model Board of Visitors Role: Principal Investigator $4,000
June 2018 Respiratory CPG Development Hunter‘s Hope Foundation Role: Principal Investigator $10,000
July 2017 ASPIRO A Phase 1/2, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Preliminary Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) Patient Audentes Therapeutics Role: Contributor
October 2016 A Prospective, Non Interventional Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects Aged 3 Years and Younger Audentes Therapeutics Role: Contributor
Xilei Xu Chen and Geovanny F. Perez. (2023) Link between nocturnal hypoventilation and hypoxia on arrhythmias/CV morbidity in neuromuscular disorders. Progress in Pediatric Cardiology (Mar), 68 doi:10.1016/j.ppedcard.2022.101601
Xilei Xu Chen and Geovanny F. Perez. (2023) Author's response: Link between nocturnal hypoventilation and hypoxia on arrhythmias/CV morbidity in neuromuscular disorders. Progress in Pediatric Cardiology (Mar), 68 doi:10.1016/j.ppedcard.2023.101621
Perez G, Young L, Kravitz R, Sheehan D, Adang L, Van Haren K, Lin JL, Jaffe NN, Kuo D, Ball L, Keller J, Sank J, DiVito D, Naime S. (2022) Pulmonological issues. Current problems in pediatric and adolescent health care (Dec), 52(12): 101313.
Perez G, Koumbourlis A. (2015) In: "Pulmonary Function Test in the Intensive Care Unit". Nova Science Publishers
Professional Memberships:
American College of Chest Physicians (2017–present)
American Academy of Pediatrics Section on Pediatric Pulmonology: Fellow (2014–present)
American Academy of Pediatrics: Fellow (FAAP) (2011–present)
American Federation of Medical Research (2011–present)
American Thoracic Society (2011–present)
European Respiratory Society (2011–present)
Faculty of 1000 (2011–present)
Presentations:
"Asthma Updates" Buffalo Pediatric Society (2022)
"Pediatric Pulmonary Board Review" Pediatric Residency Lecture Series (2022)
"Latinx in Healthcare, The Need for Latinx Diversity and Representation in Health Care" (2021)
"Abordaje del recien nacido con hipoxia" XXI Congreso Internacional De Pediatría De La SEPP 2021 (2021)
"Asthma" the National Association of Pediatric Nurse Practitioners, Western New York Chapter, annual conference (2021)
"Residents Respiratory Day" Pediatric Residency Lecture Series (2021)
"Pediatric Asthma Management Guidelines Focused 2020 Updates" Mini Grand Rounds; Oishei Children's Hospital (2021)
"Pulmonary Care in Patients with Congenital Muscular Dystrophy" KSSK CMD Chats: A Pulmonary Guide Web Series; Cure CMD (2021)
"Cuidados en los ninos con enfermedad neuromuscular" I Simposio Enfermedad Neuromuscular en niños, Fundacion HOMI (2020)
"Chronic Respiratory Failure" Pediatric Pulmonary Board Review Course; American College of Chest Physicians (2020)
"Invasive Ventilation; tracheostomy" American College of Chest Physicians Pulmonary Board Review (2020)
"Restrictive Lung Disease" American College of Chest Physicians Pulmonary Board Review (2020)
"Restrictive Lung Disease" Pediatric Pulmonary Board Review Course; American College of Chest Physicians (2020)
"Bronchiolitis" Pediatric Residents Lecture Series (2020)
"Mechanisms of Hypoxemia and Hypoventilation in Neuromuscular Respiratory Failure" International Conference; American Thoracic Society; Management of Neuromuscular Respiratory Failure Syndromes: Nippv for Day, Night and the Soccer Field (2019)
"Care of the Neuromuscular Patient and Care of the Patient with Severe BPD" Respiratorias Meeting; Sociedad Ecuatoriana de Tisiologia y Enfermedades (2019)
"Factors Associated with Extubation Failure in Pediatric Patients with Neuromuscular Disorders: A Retrospective Study" Annual Meeting; Pediatric Academic Societies (2019)
"Current Concepts on Prematurity" Pediatric Talk; HCAM Hospital (2018)
"Chronic Respiratory Failure (Noninvasive and Invasive Ventilation Tracheostomy)" Pulmonary Board Review; American College of Chest Physicians (2018)
"Restrictive Lung Disease" Pulmonary Board Review; American College of Chest Physicians (2018)
"Choosing Ventilatory Support for Patients with Neuromuscular Disorders" International Conference; American Thoracic Society (2017)
"Airway Molecular Phenotyping in Prematurity Identifies Intrinsic Secretory Signatures Linked to Th2 Inflammation and Airway Remodeling" International Congress on Pediatric Pulmonology; CIPP (2016)
"Cystic Fibrosis Review for Parents" Cystic Fibrosis Symposium; Children’s National Medical Center/Hospital Carlos Andrade de Marin/Hospital Eugenio Espejo (2012)
"Complications of Nissen Fundoplication after Gastrostomy Tube Placement in CF Patients" North American Cystic Fibrosis Conference; Cystic Fibrosis Foundation; Pediatric Fellow Session (2011)
"Respiratory Care of Children with Neuromuscular Disease" I Symposium on Neuromuscular Disease in Children; HOMI Hospital de la Misericordia Foundation
American Academy of Pediatrics, Pediatric Pulmonary; Subspecialty Board Member (2023–2029)
Interviewer of residency candidates for the Department of Pediatrics, State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences; Interviewer (2021–present)
Department of Pediatrics Medical Study Small group faculty member, meet with rotating 3rd and 4th year medical students to discuss their pediatric clinical rotation, teach and provide feedback; Facilitator (2020–present)
Responsible for the Pulmonary Function Test laboratory, as well as inpatient respiratory services. Committee member for the selection of new respiratory equipment; Medical Director Pulmonary, John R. Oishei Children's Hospital (2020–present)
Medical Student Supervisor, Jacobs School of Medicine and Biomedical Sciences; Medical student supervisor (2020–present)
Interviewer of residency candidates for the Department of Pediatrics, State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences (2017–present)
Children's National Medical Center: Pediatric Surgery Verification Program Liaison (2017–2019)
Children's National Medical Center: Antimicrobial Subcommittee; Committee Member (2017–2019)
American Thoracic Society International Conference: Pediatric Asthma Mini Symposium; Co-Chair (2017)
Cure CMD: Pulmonary Guidelines Committee; Committee Member (2017)
UBMD Pediatrics Division of Pulmonology and Sleep Medicine 1001 Main Street Buffalo, New York 14203 Phone: (716) 323-0110 Fax: (716) 323-0296 gperez9@buffalo.edu