Population health looks beyond the treatment of individual patients to understand the community, regional and system-level forces shaping health outcomes. That includes inequities driven by race, socioeconomic status, geography, and structural barriers that influence how people live, work, and access care. Host Allison Brashear, MD, MBA, welcomes two guests who are leading this work nationally and here at UB, helping define the future of population health in our region: Leonard E. Egede, MD, and Rebekah J. Walker, PhD.