Our facility offers instrumentation and the technical expertise required to express and purify milligram quantities of soluble and membrane proteins for biophysical and structural characterization.
At the core of our facility is a high-throughput screening laboratory for use in the identification of initial crystallization leads for a target protein.
The laboratory uses two sets of 1536 crystallization cocktails for soluble and membrane proteins, set up using the microbatch-under-oil crystallization technique. We monitor experiments using digital recordings of the results.
Full laboratory facilities are available for the identification of protein crystals, optimization of crystallization leads and structure determination using X-ray crystallography.
Hauptman Woodward Medical Research Institute
Buffalo Niagara Medical Campus
700 Ellicott Street