Engaged in diverse basic, translational and clinical research, our faculty routinely publish in prestigious journals and successfully compete for major grants from national funders.
Nguyen L, Ajredini R, Guo S, Romano LEL, Tomas RF, Bell LR, Ranum PT, Zu T, Bañez Coronel M, Kelley CP, Redding-Ochoa J, Nizamis E, Melloni A, Connors TR, Gaona A, Thangaraju K, Pletnikova O, Clark HB, Davidson BL, Yachnis AT, Golde TE, Lou X, Wang ET, Renton AE, Goate A, Valdmanis PN, Prokop S, Troncoso JC, Hyman BT, Ranum LPW. (2025) CASP8 intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer's disease risk. Proceedings of the National Academy of Sciences of the United States of America (Feb), 122(7): e2416885122.
Passias PG, Tretiakov P, Onafowokan OO, Das A, Lafage R, Smith JS, Line BG, Nayak P, Diebo B, Daniels AH, Gum JL, Hamilton DK, Buell TJ, Soroceanu A, Scheer JK, Eastlack RK, Mullin JP, Schoenfeld AJ, Mundis GM, Hosogane N, Yagi M, Mummaneni PV, Chou D, Fu KM, Than KD, Anand N, Okonkwo DO, Wang MY, Klineberg E, Kebaish KM, Lewis S, Hostin R, Gupta M, Lenke L, Kim HJ, Ames CP, Shaffrey CI, Bess S, Schwab F, Lafage V, Burton D. (2025) When is staging complex adult spinal deformity advantageous? Identifying subsets of patients who benefit from staged interventions. Journal of neurosurgery. Spine (Feb), 42(2): 185-192.
Lee TM, Ware SM, Kamsheh AM, Bhatnagar S, Absi M, Miller E, Purevjav E, Ryan KA, Towbin JA, Lipshultz SE. (2025) Genomics of pediatric cardiomyopathy. Pediatric Research (Feb) doi:10.1038/s41390-025-03819-2
Goyal M, Ospel JM, Ganesh A, Dowlatshahi D, Volders D, Möhlenbruch MA, Jumaa MA, Nimjee SM, Booth TC, Buck BH, Kennedy J, Shankar JJ, Dorn F, Zhang L, Hametner C, Nardai S, Zafar A, Diprose W, Vatanpour S, Stebner A, Bosshart S, Singh N, Sebastian I, Uchida K, Ryckborst KJ, Fahed R, Hu SX, Vollherbst DF, Zaidi SF, Lee VH, Lynch J, Rempel JL, Teal R, Trivedi A, Bode FJ, Ogungbemi A, Pham M, Orosz P, Abdalkader M, Taschner C, Tarpley J, Poli S, Singh RJ, De Leacy R, Lopez G, Sahlas D, Chen M, Burns P, Schaafsma JD, Marigold R, Reich A, Amole A, Field TS, Swartz RH, Settecase F, Lenzsér G, Ortega-Gutierrez S, Asdaghi N, Lobotesis K, Siddiqui AH, Berrouschot J, Mokin M, Ebersole K, Schneider H, Yoo AJ, Mandzia J, Klostranec J, Jadun C, Patankar T, Sauvageau E, Lenthall R, Peeling L, Huynh T, Budzik R, Lee SK, Makalanda L, Levitt MR, Perry RJ, Hlaing T, Jahromi BS, Singh P, Demchuk AM, Hill MD, . (2025) Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion. The New England journal of medicine (Feb).
Johnson BJ, Chadwick PM, Pryde S, Seidler AL, Hunter KE, Aberoumand M, Williams JG, Lau HI, Libesman S, Aagerup J, Barba A, Baur LA, Morgillo S, Sanders L, Taki S, Hesketh KD, Campbell K, Manson A, Hayes A, Webster A, Wood C, O'Connor DA, Matvienko-Sikar K, Robledo K, Askie L, Wolfenden L, Taylor R, Yin HS, Brown V, Fiks A, Ventura A, Ghaderi A, Taylor BJ, Stough C, Helle C, Palacios C, Perrin EM, Reifsnider E, Rasmussen F, Paul IM, Savage JS, Thomson J, Banna J, Larsen J, Joshipura K, Ong KK, Karssen L, Wen LM, Vitolo M, Røed M, Bryant M, Rivera MC, Messito MJ, Golova N, Øverby NC, Gross R, Lakshman R, Byrne R, Rothman RL, O. (2025) Behavioural components and delivery features of early childhood obesity prevention interventions: intervention coding of studies in the TOPCHILD Collaboration systematic review. The international journal of behavioral nutrition and physical activity (Feb), 22(1): 14. doi:10.1186/s12966-025-01708-9
Research Grants
A phase 3 double-blind study to evaluate the efficacy and safety of oral ozanimod compared to oral fingolimod in children and adolescents with relapsing-remitting multiple sclerosis. Michael Dwyer, III (Co-Investigator). Bristol Myers Squibb. $1,649,376. 6/1/2023-12/1/2032.
CTSA State University of New York at Buffalo. Zackary Falls (Contributor). National Center for Advancing Translational Sciences (NCATS). $29,204,726. 1/1/2025-12/1/2031.
Clinical and Translational Science Award. Core Operations Special Populations. Ralph Benedict (Co-Investigator). NIH. $29,204,726. 1/1/2025-12/1/2031.
Clinical and Translational Science Award. University at Buffalo Clinical and Translational Science Institute. Timothy Murphy (Principal Investigator). NIH. 1/1/2025-12/1/2031.
Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy. Pablo Paez (Co-Investigator). National Institute of Neurological Disorders and Stroke (NINDS). $1,950,000. 2/1/2025-1/1/2030.
Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy. Daesung Shin (Principal Investigator). NIH. $2,013,407. 12/1/2024-12/1/2029.
Overdose Data to Action in States (OD2A): Bio surveillance. Brian Clemency (Principal Investigator). Centers for Disease Control and Prevention (Subaward from NYS Department of Health/Health Research Inc.). $250,000. 9/1/2024-8/1/2029.
Rhythm Evaluation for AntiCoagulaTion for Atrial Fibrillation (REACT AF). Anne Curtis (Co-Investigator). NIH. $66,278. 8/1/2023-7/1/2029.
Leveraging small molecule inhibitors to improve CD19 CAR T cell immunotherapy for KMT2A-rearranged ALL. Lisa Niswander (Principal Investigator). NIH/NCI. 7/1/2024-7/1/2029.
Characterizing the role of Elevated dNTP pools in sensitizing the replisome. Jennifer Surtees (Principal Investigator). NIGMS. $2,448,745. 9/1/2024-6/1/2029.
NIMHD Center of Excellence in Investigator Development and Community Engagement. Timothy Murphy (Principal Investigator). NIH. $3,600,000. 7/1/2024-6/1/2029.
Molecular Mechanisms of Severe Diabetic Retinopathy. Joshua Jianxin Wang (Co-Investigator). NIH/NEI. $2,374,855. 2/1/2020-5/1/2029.