Recent Publications and Grants

Engaged in diverse basic, translational and clinical research, our faculty routinely publish in prestigious journals and successfully compete for major grants from national funders.

Recent Publications

Tooley JG, Catlin JP, Tooley CES. (2023) METTLing in Stem Cell and Cancer Biology. Stem cell reviews and reports (Jan), 19(1): 76-91.
Anzman-Frasca S, McGovern L, Ferrante MJ, Drozdowsky J, Epstein LH, Hollis-Hansen K, Lassetter L, Leone LA, Tan S. (2023) Effects of a grocery shopping intervention designed to improve diet adherence in diabetes: a randomized trial. Obesity (Silver Spring, Md.) (Jan), 31(1): 62-73.
Arystarkhova E, Toustrup-Jensen MS, Holm R, Ko JK, Lee KE, Feschenko P, Ozelius LJ, Brashear A, Vilsen B, Sweadner KJ. (2023) Temperature instability of a mutation at a multidomain junction in Na,K-ATPase isoform ATP1A3 (p.Arg756His) produces a fever-induced neurological syndrome. The Journal of biological chemistry (Jan), 299(1): 102758. doi:doi: 10.1016/j.jbc.2022.102758
Van Roekel NL, Deliberato DG, Bayers-Thering M, Phillips MJ. (2023) Superficial Femoral Artery Pseudoaneurysm After Intra-articular Adductor Canal Pain Catheter Placement for Total Knee Arthroplasty. Orthopedics (Jan), 46(1): e58-e61.
Bisson LJ. (2023) Letter to the Editor. Editorial Commentary: We Should Be Cautious About Using Catching and Locking as an Indication for Knee Arthroscopy: Mechanical Symptoms May Be Multifactorial in Their Causes. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (Jan), 39(1): 100-101.
Kemper C, Ferreira VP, Paz JT, Holers VM, Lionakis MS, Alexander JJ. (2023) Complement: The Road Less Traveled. Journal of Immunology (Jan), 210(2): 119-125.
Williams JB, Cao Q, Wang W, Lee YH, Qin L, Zhong P, Ren Y, Ma K, Yan Z. (2023) Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature Communications (Jan)(14): 91. doi:10.1038/s41467-022-35749-6
Williams JB, Cao Q, Wang W, Lee YH, Qin L, Zhong P, Ren Y, Ma K, Yan Z. (2023) Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications (Jan), 14(1): 91. doi:10.1038/s41467-022-35749-6
Kumari R, Sharma SD, Kumar A, Ende Z, Mishina M, Wang Y, Falls Z, Samudrala R, Pohl J, Knight PR, Sambhara S. (2023) Antiviral Approaches against Influenza Virus. Clinical microbiology reviews (Jan)e0004022.
Kumari R, Sharma SD, Kumar A, Ende Z, Mishina M, Wang Y, Falls Z, Samudrala R, Pohl J, Knight PR, Sambhara S. (2023) Antiviral Approaches against Influenza Virus. Clinical microbiology reviews (Jan)e0004022.
Conner MM, Schaner Tooley CE. (2023) Three's a crowd - why did three N-terminal methyltransferases evolve for one job?. Journal of cell science (Jan), 136(2).
Ong, A. O'Brian, M.R. (2023) The Bradyrhizobium japonicum fsrB gene is essential for utilization of structurally diverse ferric siderophores to fulfill its nutritional iron requirement. Molecular Microbiology (Jan) doi:https://doi.org/10.1111/mmi.15028
Timilsina U, Stavrou S. (2023) SERINC5: One antiviral factor to bind them all. PLoS pathogens (Jan), 19(1): e1011076.
Bruggemann L, Falls Z, Mangione W, Schwartz SA, Battaglia S, Aalinkeel R, Mahajan SD, Samudrala R. (2023) Multiscale Analysis and Validation of Effective Drug Combinations Targeting Driver KRAS Mutations in Non-Small Cell Lung Cancer. International journal of molecular sciences (Jan), 24(2) doi:10.3390/ijms24020997
Bruggemann L, Falls Z, Mangione W, Schwartz SA, Battaglia S, Aalinkeel R, Mahajan SD, Samudrala R. (2023) Multiscale Analysis and Validation of Effective Drug Combinations Targeting Driver KRAS Mutations in Non-Small Cell Lung Cancer. International journal of molecular sciences (Jan), 24(2). doi:10.3390/ijms24020997
Kenney PO, Chang AJ, Krabill L, Hicar MD. (2023) Decreased Clinical Severity of Pediatric Acute COVID-19 and MIS-C and Increase of Incidental Cases during the Omicron Wave in Comparison to the Delta Wave. Viruses (Jan), 15(1). doi:10.3390/v15010180
Byrwa DJ*, Perez GF, Roach CM, Prentice S, Goetz DM. (2023) Airway clearance therapy in the school environment: Retrospective analysis of a cohort of pediatric patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society (Jan)
Ge Y, Chen X, Nan N, Bard J, Wu F, Yergeau D, Liu T, Wang J, Mu X. (2023) Key transcription factors influence the epigenetic landscape to regulate retinal cell differentiation. Nucleic acids research (Jan) doi:10.1093/nar/gkad026
Nealon CL, Halladay CW, Kinzy TG, Simpson P, Canania RL, Anthony SA, Roncone DP, Sawicki Rogers LR, Leber JN, Dougherty JM, Sullivan JM, Wu WC, Greenberg PB, Iyengar SK, Crawford DC, Peachey NS, Cooke Bailey JN; VA Million Veteran Program. (2022) Development and Evaluation of a Rules-based Algorithm for Primary Open-Angle Glaucoma in the VA Million Veteran Program. Ophthalmic Epidemiol. (Dec), 29(6): 640-648.
Kuo CC, Piccillo EM, DeGiovanni JC, Kabalan M, Zimmer G, Carr MM. (2022) Acute Herpetic Nasopharyngitis in an Adult Patient: A Case Report and Literature Review. The Annals of otology, rhinology, and laryngology (Dec), 131(12): 1390-1393.

Research Grants

NIH NCATS ASPIRE Design Award. Ram Samudrala (Principal Investigator). NIH. $100,000. 9/1/2019-1/1/2030.
NIH NCATS ASPIRE Reduction-to-Practice Award. Ram Samudrala (Co-Principal Investigator). NCATS. $1,220,000. 8/1/2021-1/1/2030.
NIH/NIAID (Morse) HIV/AIDS Clinical Trial Unit. Andrew Talal (Co-Principal Investigator). 12/1/2013-4/1/2028.
A Ribozyme Rescue Strategy for Dry Age-Related Macular Degeneration. John Sullivan (Principal Investigator). VA Central Office. $330,000. 1/1/2025-12/1/2027.
Exercise Reset for Concussion - Modifying the Buffalo Concussion Protocol for Application in a Military Environment. John Leddy (Principal Investigator). Department of Defense (CDMRP). 1/1/2023-12/1/2027.
NIH Application R01-HD108253-01A1 “The Impact of Hormonal Modulation on Systemic Inflammation and Central Sensitization”. Robert Taylor (Co-Investigator). NICHD. 11/1/2022-12/1/2027.
Modulation of oligodendrocyte development by voltage-operated calcium channels. Pablo Paez (Principal Investigator). National Institute of Neurological Disorders and Stroke (NINDS). $1,993,750. 12/1/2021-11/1/2027.
Transcriptomic and Circuitry Aberrations in Alzheimer’s Disease. Zhen Yan (Principal Investigator). NIA. $3,710,395. 12/1/2022-11/1/2027.
Exercise Reset: Application of the Buffalo Concussion Protocol for the military. Barry Willer (Co-Principal Investigator). Department of Defence; Defence Health Agency. $7,601,790. 9/1/2022-10/1/2027.
Epigenetic Mechanisms That Drive Genetic Risk for Juvenile Arthritis. James Jarvis (Principal Investigator). NIH/NIAMS. $3,047,449. 10/1/2022-9/1/2027.
UB Family Medicine Residency Didactic Training in Behavioral Health. Linda Kahn (Co-Investigator). HRSA. $2,500,000. 12/1/2022-9/1/2027.
Buffalo Research Innovation in Genomic and Healthcare Technology (BRIGHT) Short-Term Training and Education. Zackary Falls (Co-Investigator). National Library of Medicine. $667,598. 9/1/2022-8/1/2027.
Mab Passive Vaccination against Acinetobacter baumannii. Thomas Russo (Co-Investigator). NIAID/NIH. $485,053. 9/1/2022-8/1/2027.
Buffalo Research Innovation in Genomic and Healthcare Technology (BRIGHT) Short-Term Training and Education. Ram Samudrala (Principal Investigator). NIH. $672,596. 9/1/2022-8/1/2027.
Disease progression modeling of bladder cancer. Yijun Sun (Co-Principal Investigator). NIH. $2,500,000. 9/1/2022-8/1/2027.

Recent Publications and Grants

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Research Grants

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