Psychiatry Cell Biology Laboratory

Located on the main floor of ECMC, this fully equipped basic research laboratory specializes in studies of cell signaling in psychiatric disorders.

Professor and research assistant working in Psychiatry Cell Biology Laboratory.

Elsa Daurignac, PhD, research assistant professor, and volunteer research assistant Evan Kristansen measure reagents to prepare to add them to a sample solution.

In addition to preparing specimens for clinical trials, the laboratory specializes in studies of cell signaling in psychiatric disorders and the metabolic effects of olanzapine in healthy participants. We are particularly interested in measuring aspects of intracellular calcium ion signaling in blood platelets of people with bipolar disorder and determining the predictive value of the effect of lithium on intracellular calcium levels in the treatment outcome of these individuals.

Olanzapine, an atypical antipsychotic approved by the FDA for the treatment of schizophrenia and bipolar disorder, is associated with weight gain, hyperlipidemia and Type 2 diabetes among psychiatric patients. Our study is designed to illuminate the processes that underlie these effects but focuses on individuals without psychiatric disorders.

This facility has its own suite of equipment on-site, including a spectrophotometer, Beckman Coulter counter, centrifuges and freezers.

Select students and residents may train here as research assistants.

Director

Dubovsky, Steven

Steven Dubovsky, MD

Professor and Chair; Adjoint Professor of Psychiatry and Medicine, University of Colorado School of Medicine

University at Buffalo - Psychiatry, Erie County Medical Center, 462 Grider St. Room 1168 Buffalo, NY 14215

Phone: (716) 898-5940; Fax: 716-898-4538

Email: dubovsky@buffalo.edu