Corey Knowles

The goal of my research is to understand the mechanisms of stress sensing and adaptation in the human pathogen C. neoformans. After encountering temperature and oxidative stress from the human host, C. neformans rapidly reprograms its translatome, which is accompanied by a transient translational repression. We seek to understand how stress from the host results in translational repression in C. neoformans, and the subsequent signalling pathways that lead to remodeling the translatome to one which is stress responsive. 

• John Panepinto, PhD

• PhD, University at Buffalo, New York