John J. Leddy MD, FACSM, FACP, FAMSSM

John Leddy

John J. Leddy
MD, FACSM, FACP, FAMSSM

Clinical Professor

Department of Orthopaedics

Jacobs School of Medicine & Biomedical Sciences


Specialty/Research Focus

Concussion; Sports Medicine; Sports Medicine - Internal Medicine

Contact Information
111 North Maplemere #100
Amherst, NY 14228
Buffalo, New York 14221
Phone: (716) 204-3200
leddy@buffalo.edu


Patient Care

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD


Professional Summary:

As a primary care sports medicine physician, my goal is to provide the best evidence-based evaluation and treatment practices to patients with concussion and post-concussion syndrome and to conduct clinical and physiological research on these conditions. I currently serve as medical director of the University at Buffalo Concussion Management Clinic, which is located at UB South Campus. This is the first center in the United States to use a standardized treadmill test to establish recovery from concussion and to use exercise in the rehabilitation of patients with prolonged concussion symptoms. I’m also the director of outcomes research for the Department of Orthopaedics and program director for the UB Primary Care Sports Medicine fellowship.

My primary research interest is the investigation of the basic mechanisms of the disturbance of whole body physiology in concussion and how to help to restore the physiology to normal to help patients recover to safely return to activity and sport. I have published in the fields of orthopedics, sports medicine, physiology, nutrition, concussion and post-concussion syndrome.

As a professor of Clinical Orthopaedics, Internal Medicine, and Rehabilitation Sciences at the University at Buffalo School of Medicine and Biomedical Sciences, I enjoy educating the next generation of physicians. I am proud to say that the educational experience at UB exposes young physicians to exceptional patient care based upon the latest research and that their experience is informed and enhanced by immersion in the research experience itself.

Education and Training:

  • American College of Physicians (2009)
  • American College of Sports Medicine (1998)
  • Faculty Development Fellow in Primary Care Sports Medicine, State University of New York at Buffalo (1991)
  • Fellowship, Union Memorial Hospital (1991)
  • MD, Internal Medicine Residency, New England Deaconess Hospital and Harvard University (1988)
  • Residency, New England Deaconess Hospital and Harvard University (1988)
  • MD, Medicine, State University of New York at Buffalo (1985)
  • BS, Biology, Fordham University, Summa Cum Laude (1981)

Employment:

  • Fellow, American Medical Society for Sports Medicine (FAMSSM) (2021-present)
  • Adjunct Clinical Professor, Exercise & Nutrition Sciences, University at Buffalo (2019-present)
  • Fellow, American College of Physicians (FACP) (2009-present)
  • Team Physician, Division 1 Football, University at Buffalo (1991-present)
  • Professor of Rehabilitation Sciences, University at Buffalo School of Health Related Professions (2016-present)
  • Clinical Professor of Orthopaedics, Orthopaedics, University at Buffalo/Jacobs School of Medicine & Biomedical Sciences (2014-present)
  • Director of Outcomes Research, Orthopaedics, University at Buffalo (2014-present)
  • Medical Director, University at Buffalo Concussion Management Clinic (2007-present)
  • Assistant Professor of Rehabilitation Services, Rehabilitation Medicine, University at Buffalo Jacobs School of Medicine & Biomedical Sciences (2004-present)
  • Fellow, American College of Sports Medicine (FACSM) (1998-present)
See all (23 more)

Awards and Honors:

  • 2024 North American Brain Injury Society (NABIS) Award for Innovative Clinical Treatment (2024)
  • 2022 Stockton Kimball Award for Outstanding Scholar and Researcher (2022)
  • 2021 SUNY Chancellor’s Award for Excellence in Scholarship and Creative Activities. (2021)
  • Clinical Research Achievement Award (2021)
  • Best Overall Research Award, American Medical Society for Sports Medicine (2016)
  • Castle Connolly‘s Top Doctor, 2005-2017 (2016)
  • Eastern Athletic Trainer‘s Association David G. Moyer Award (2013)
  • The Brain Injury Association of New York State (BIANYS) Marie Ivanchich Memorial Award (2013)
  • AMA Physician‘s Recognition Award in Continuing Medical Education (2000)
  • American Academy of Family Physicians Recognition for Teaching (1993)
  • Alpha Omega Alpha (1984)
  • Phi Beta Kappa (1981)
  • N.C.C.C. Outstanding Contribution to the Athletic Program

Research Centers:

  • Buffalo Neuroimaging Analysis Center

Grants and Sponsored Research:

  • January 2023–December 2027
    Exercise Reset for Concussion - Modifying the Buffalo Concussion Protocol for Application in a Military Environment
    Department of Defense (CDMRP)
    Role: Principal Investigator
  • September 2022–August 2026
    Treatment Optimization of Brain-injured injured Warfighters: A Prescribed Sub-symptom Exercise Treatment (TOBI-SET)
    DoD CDMRP
    Role: Co-Investigator
    $3,000,000
  • October 2023–March 2026
    TRANSCENDENT - Transforming Research by Assessing Neuroinformatics across the Spectrum of Concussion by Embedding iNterdisciplinary Data-collection to Enable Novel Treatments
    Ontario Brain Institute (OBI)
    Role: Co-Principal Investigator
    $3,907,602
  • January 2024–December 2024
    Feasibility of Aerobic Exercise for Recovery from Work-related Concussion
    NIH National Center for Advancing Translational Science Award
    Role: Co-Investigator
    $42,161
  • September 2021–August 2023
    Refinement of a rapid saliva miRNA diagnostic test for concussion
    NINDS/NIH National Institutes of Neurological Diseases and Stroke Small Business Technology Transfer program (STTR)
    Role: Principal Investigator
  • June 2021–May 2023
    Exercise Therapy for mild traumatic brain injury (mTBI) and persistent post-concussion symptoms (PPCS) across the lifespan.
    National Health and Medical Research Council (Australia)
    Role: Consultant
  • January 2022–December 2022
    Assessing Epigenetic and Protein Biomarkers During Recovery from Concussion
    UB Clinical and Translational Science (CTSA)
    Role: Co-Investigator
  • May 2017–March 2022
    Treatment of Meniscal Problems in Osteoarthritis
    Brigham and Women's Hospital
    Role: Co-Investigator
  • February 2016–March 2022
    Physiological mechanisms of a biomarker of recovery from concussion
    NIH/NINDS ROI
    Role: Principal Investigator
  • January 2021–December 2021
    Classifying sports related concussions by symptom profiles
    UB Clinical and Translational Science (CTSA)
    Role: Co-Investigator
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Journal Articles:

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Books and Book Chapters:

  • Leddy JJ, Izzo J. (2010) Clinical Challenges in Hypertension. In: Exercise, athletes and blood pressure. Atlas Medical Publishing
  • Leddy JJ, Girard Eberle S. (2009) In: Medical and Nutritional Aspects of the Female Athlete Triad.
  • Robert Smolinski, John Leddy, Philip Stegemann. (1996) Rotator Cuff Disease.

Abstracts:

  • Leddy JJ, Polak P, Baker JG, Zivadinov R, Willer B. (2014) Advanced MRI Techniques Differ in Concussion Assessment. Clin J Sport Med, (Jan)
  • Leddy JJ, Hinds A, Miecznikowski J, Willer B. (2013) Autonomic Dysfunction in Post-Concussion Syndrome Revealed During Exercise. Clinical Journal of Sports Medicine, (Jan)
  • Leddy JJ, Seemant F, Hinds A, Wojnowski K. (2013) The Influence of Concussion on Sleep Disturbance. Clinical Journal of Sports Medicine, (Jan)
  • Leddy JJ, Lo Bue-Estes C, Burton H, Willer B, Horvath PJ. (2008) Changes in Cognitive Function During and Following Short-Term Manimal Aerobic Exercise in Young Women. Med Sci Sports Exerc, (Jan) S453
  • Leddy JJ, Kozlowski KF, Pendergast DR, Donnelly J, Fung M, Willer B. (2008) Quantitative Progressive Exervise Rehabilitation (QPER) for Post Concussion Syndrome. Med Sci Sports Exerc, (Jan) S68
  • Leddy JJ, Horvath PJ, Lo Bue-Estes C, Browne RW, Burton H, Griffin K, Willer B. (2008) Salivary and Plasma Markers During and Following Short-Term Maximal Aerobic Exercise Assessed During Cognitive Assessment. Med Sci Sports Exerc, (Jan) S453
  • Leddy JJ, DeNysschen C, Burton H, Horvath P, Browne R. (2007) Resistance Training, Protein Supplementation and Cardiovascular Disease Risk Reduction. Med Sci Sports Exerc, (Jan) S376
  • Leddy JJ, Mahaney M, Horvath PJ, Dorn J, Muscarella J. (2006) Prevalence of Risk for Eating Disorders in an NCAA Division I Wrestling Program. Med Sci Sports Exerc, (Jan)
  • Leddy JJ, Temple J, Neaderhiser BJ, Salis RJ, Epstein LH. (2006) Dopamine Receptor Genotype and Food Reinforcement Phenotype Interact to Increase Energy Intake. Obesity, (Jan)
  • Leddy JJ, Darling S, Kroetsch B, Willer C, Willer B. (2006) Types and Causes of Injury in a Youth Ice Hockey Program. Med Sci Sports Exerc, (Jan)
See all (31 more)

Professional Memberships:

  • Undersea and Hyperbaric Medical Society; Member (1995–2002)
  • American Board of Internal Medicine; Diplomate (1988–present)
  • American College of Sports Medicine; Member 1991 Fellow 1998-Present
  • American Medical Society for Sports Medicine; Member 1997-Present Fellow 2021-Present
  • American College of Physicians; Member 1997-Present Fellow 2009-Present

Presentations:

  • "Concussion" WNY School Nurses Association (2021)
  • "Concussion for Parents, Teachers and Coaches" Nichols High School (2020)
  • "Evaluation of concussion and persistent post-concussive symptoms" Catholic Health System Medicine Grand Rounds (2020)
  • "Internist evaluation of concussion and persistent post-concussive symptoms" University at Buffalo Citywide Internal Medicine Grand Rounds (2020)
  • "Concussion in the ED" University at Buffalo Department of Emergency Medicine Grand Rounds (2020)
  • "Concussion Update 2020" University at Buffalo Department of Neurology Grand Rounds (2020)
  • "Concussion-Epidemiology to Physiology" University at Buffalo Department of Epidemiology (2020)
  • "RCT of Exercise for Concussion" Clinical and Translational Research Center. Jacobs School of Medicine (2019)
  • "Evaluation and Management of Concussion" UB Sports Medicine Fellowship Lecture (2019)
  • "Evaluation and Treatment of Concussion and PPCS" Dent Neurologic Group (2019)
See all (214 more)

Service Activities:

  • Chair of the Ad Hoc Committee on Promotions to Clinical Ranks for the 2020-21 academic year; Chair (2020–2021)
  • Appointed to AD Hoc Committee Promotions to Clinical Ranks; Member (2019–2022)
  • Pink Concussions'; Professional Advisory Board Member (2018–present)
  • UB Internal Reviewer for CTSA grants and IMPACT grants; Internal Reviewer (2017–present)
  • Presentation; Buffalo Museum of Science Presentation of the Science of Concussion (2015–present)
  • Buffalo Bills Football Team and Buffalo Sabres Hockey Team; Concussion Consultant (2015–present)
  • Harbour Center, Buffalo NY; Medical coverage 2015 World Ice Hockey Sledge Tournament (2015–present)
  • Director of Outcomes Research for the Department of Orthopaedics; Director (2014–present)
  • American Board of Family Medicine: participant in the standard setting exercise to define the minimum passing score for the Sports Medicine C A Q examination.; Participant (2014–present)
  • UB Recreation Facility Committee; Member (2013–present)
  • Chronic Effects of Neurotrauma Consortium Projects 1 (CENC-P1); Scientific reviewer and panel member for the Chronic Effects of Neurotrauma Consortium Projects 1 (CENC-P1) onsite peer review panel for the 2012 Psychological Health and Traumatic Brain Injury Research Program (PH/TBI RP) for the Department of Defense (DoD). Congressionally Directed Medical Research Programs (CDMRP).; (2013)
  • Chronic Effects of Neurotrauma Consortium Projects 1 (CENC-P1) onsite peer review panel for the 2012 for the Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP).; Scientific Reviewer and panel member (2013)
  • Buffalo Seminary; Board of Trustees (2012–2015)
  • Defense and Veterans Brain Injury Center - Defense Centers of Excellence for Psychological health and Traumatic Brain Injury Clinical Initiatives; Scientific Panel Member (2012–2013)
  • University at Buffalo Faculty Senate Athletics and Recreation Committee; Chairman (2012–present)
  • Farber Hall Relocation Committee; Member (2012–present)
  • American Medical Society for Sports Medicine; Research Committee (2012–present)
  • Research Committee, American Medical Society for Sports Medicine (2012–2014)
  • American Medical Society for Sports Medicine - Research Committee; Member (2012–2014)
  • Defense and Veterans Brain Injury Center; Member (2012–2013)
  • University at Buffalo Committee on Promotions to Clinical Ranks; Member (2010–2013)
  • University at Buffalo Interdisciplinary Research Development Fund Program (2009) and the 2010 Pilot and Collaborative Translational and Clinical Studies Program; Editorial Board: Reviewer (2009–2010)
  • American College of Physicians; Fellow (2009–present)
  • North American Brain Injury Society, Blast Injury Institute and the Brain Injury Association of America. Washington DC; Mild TBI and PTSD Working Group for the 2007 Brain Injury Consensus Conference (2007)
  • University at Buffalo Concussion Management Clinic; Medical Director (2006–present)
  • University at Buffalo Sports Medicine Fellowship, for the Departments of Orthopaedics and Family Medicine.; Program Director (2004–present)
  • Program Director, Sports Medicine Fellowship Departments of Orthopaedics and Family Medicine (2004–present)
  • Professional Development Committee, Department of Occupational Therapy. Academic review of Dr. Nadine Fisher; Member (2002–present)
  • Steering Committee Dietetic Internship Program; Member (2002–present)
  • Faculty Council and Steering Committee of the Faculty Council; Secretary (2001–2003)
  • University at Buffalo Diving Control Board; Member (2001–present)
  • Faculty Council Representative; Department Representative (2001–2003)
  • CME Subcommittee of the Faculty Council; Member (2001–2003)
  • American College of Sports Medicine; Member (1998–present)
  • American College of Physicians; Member (1997–present)
  • Undersea and Hyperbaric Medical Society; Member (1995–2002)
  • University at Buffalo Sports Medicine Institute.; Associate Director (1994–2010)
  • The American Board of Internal Medicine; Member (1988–present)
  • UB Recreation Facility Committee; Member
  • University at Buffalo Faculty Senate Athletics and Recreation Committee; Chair
  • Farber Hall Relocation Committee; Member
  • Search Committee for Dean of the School of Health Related Professions; Member
  • Professional Development Committee; Member
  • Search Committee, School of HRP; Member
  • American Board of Internal Medicine, 1988- present.
  • Director, Outcomes Research, Department of Orthopaedics
  • American College of Sports Medicine 1991, Fellow 1998- present; Fellow
  • American Medical Society for Sports Medicine, 1997- present; Member
  • Committee on Concussion Standards in Amateur Sports; Member
  • Quality, Safety and Patient experience committee for UBA; Member
  • Brain Injury Association of New York state (BIANYS) Concussion Initiative Advisory Committee 2017; Selected to Leadership Committee 2018. Chair of Centers of Excellence Committee 2020; Member

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Contact Information

111 North Maplemere #100
Amherst, NY 14228
Buffalo, New York 14221
Phone: (716) 204-3200
leddy@buffalo.edu

This faculty member is affiliated with UBMD, practicing physicians who are also professors in the Jacobs School.

View this physician on UBMD