Core Facilities

Our school’s shared core instrumentation and transgenic animal facilities support research by UB faculty and investigators at our affiliated institutions.

These facilities not only house state-of-the-art equipment but in many cases also provide data analysis, training and grant writing consultation.

Health Sciences Collaborative Core Facilities

The Health Sciences Collaborative Core Facilities (HSCCF) provide multipurpose services to the biomedical research community at the University at Buffalo.

These centers are your source for solutions to a wide variety of research problems by leveraging the knowledge and experience of PhD-level lab managers, administrators and directors.

Confocal Microscope and Flow Cytometry Facility
11/7/23
The Confocal Microscope and Flow Cytometry Facility (CMFCF) is a Dept. Pathology and Anatomical Sciences (PAS) service center serving the researchers in the Jacobs School of Medicine and Biomedical Sciences as well as the scientists located on the South and North Campus’s at the University at Buffalo. We are part of the Health Sciences Collaborative Core Facilities and work closely with other PAS cores as well as the core facilities in the School of Dental Medicine to provide comprehensive and integrative services to solve the imaging and cytometry challenges presented by cutting-edge research programs. The imaging and cytometry instrumentation installed in the new Jacobs School of Medicine site are the latest, state of art flow cytometers and optical microscopes.
Electron Microscopy Core Lab
6/18/20
Enables researchers to obtain transmission electron microscope images of materials, polymers and biological samples; consults with investigators and assists with equipment operation.
Histology Core
8/16/23
Performs all procedures related to tissue preservation and histological analysis, including training on cryostat use and other protocols.
Multispectral Imaging Suite
10/2/19
We provide training and consultation services for students, faculty, researchers and clinicians whose work involves digital whole slide imaging (WSI) and multispectral microscopy for research, teaching or clinical interests.

Stem Cell Culture and Analysis Cores

These core facilities, part of the Western New York Stem Culture and Analysis Center, facilitate fundamental and translational stem cell research and development.

Induced Pluripotent Stem Cell Generation
6/18/20
Helps investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors.
Stem Cell Culture, Banking and Training
10/15/24
Maintains and banks stem cells, and provides stem cells and training to interested researchers.
Stem Cell Engraftment and In Vivo Analysis
3/22/20
Engrafts stem cells into mice and other model systems; quantifies cell engraftment, migration and differentiation, and analyzes the behavior consequences of neural engraftment.
Stem Cell Sequencing/Epigenomics Analysis
3/22/20
Characterizes and identifies epigenetic and transcription signatures of stem cells and their derived progeny using Next-Gen sequencing.

Other Core Facilities

Biochemistry Stockroom
7/17/24
Supplies the school and affiliated research programs with biochemical reagents.
Clinical Research Center
11/24/20
Features state-of-the-art imaging equipment dedicated to clinical and translational research, including MRI, CT and PET/CT scanners.
CTSI Translational Imaging Center
6/18/20
Features state-of-the-art imaging equipment dedicated to clinical and translational research, including MRI, CT and PET/CT scanners.
Health Sciences Instrument Shops
7/14/21
Fabricates custom equipment and repairs and modifies instruments to researchers’ needs.
Institute for Healthcare Informatics
7/11/24
Equips researchers with a HIPAA-compliant computing environment, healthcare datasets and analytic and security consulting.
Molecular Interactions
3/22/20
Offers powerful, analytical instrumentation used to study macromolecular interactions.
Next-Generation Sequencing and Expression
3/22/20
Offers high-throughput, next-generation sequencing and gene-expression analysis services, including 3’-expression, miRNA, exon and gene arrays.
Protein Expression and Crystallization
6/22/20
Offers instrumentation and the technical expertise required to express and purify milligram quantities of soluble and membrane proteins for biophysical and structural characterization.
Proteomics/Mass Spectrometry
6/18/20
Identifies proteins in cell or tissue extracts using several different liquid chromotography/mass spectrometry based approaches.
Toxicology Research Center
6/18/20
Analyzes xenobiotics and other metabolites, and supports OSHA-sponsored educational activities.