Resources for the Research Community

From UB colleagues to local, national and international investigators, we support the entire research community by sharing data, performing specialized analyses and providing access to methods and expertise that bolster basic, clinical and translational studies.

Data Collections and Tools

  • H-AI-L (Human-A.I.-Loop) for Semantic Segmentation of Whole Slide Images

    A solution for machine learning for pathologists, this tool automatically improves annotation and segmentation of medical images based on what it “learns” from the way the human user interacts with the system.

  • NFI-Regulome Database

    The Gronostajski Lab has established this database as a centralized source of information to examine the structure of the control elements of genes known to be regulated by NFI proteins. It aids in grouping genes by common regulatory elements and finding patterns of structure and function of transcription factors in control elements.

  • REDfly

    The first of its kind, REDfly is a searchable collection of known Drosophila transcriptional cis-regulatory modules (CRMs) and transcription factor binding sites (TFBSs). REDfly includes all experimentally verified fly regulatory elements along with their DNA sequence, their associated genes and the expression patterns they direct. This internationally recognized resource, developed and maintained by the Halfon lab in conjunction with the Center for Computational Research, is the most comprehensive database of regulatory elements for the higher eukaryotes.

  • Tumor Unknown

    Managed by the Department of Orthopaedics, Tumor Unknown collects diagnostic images and patient descriptions for interesting orthopaedic oncology cases on a quarterly basis. It also features tumor data in spreadsheet form and articles on bone tumors.

  • UB Biorepository

    The University at Buffalo biorepository program is designed to advance discovery and innovation in healthcare by providing a unique, centralized resource of high-quality, deeply annotated biospecimens to support present and future research studies, diagnostic development, and the creation of new therapeutics.

Services and Facilities

Buffalo Neuroimaging Analysis Center

This quantitative imaging research center conducts specialized neuroimaging studies in global and regional brain atrophy in multiple sclerosis and other neurodegenerative disorders, as well as many other quantitative MRI studies, cerebrospinal fluid imaging and optic nerve imaging.

Canon Stroke Research Center

Basic scientists and specialists with diverse clinical interests contribute to the advancement of knowledge in stroke prevention and treatment. Researchers can use the center’s scanning facilities through arrangement with the laboratory director.

  • Clinical Research Office
    2/6/19
    The Clinical Research Office (CRO) supports investigators and study staff by providing the resources and assistance necessary to conduct research in a regulatory compliant manner.
Confocal Microscopy and Flow Cytometry Center

One of the school’s Core Facilities, this laboratory offers academic and industrial investigators access to microscopy, flow cytometry, molecular imaging and real-time and quantitative PCR instrumentation for a nominal fee. Investigators may make reservations online with Calcium login credentials.

Crystallization Services

The Department of Structural Biology’s high-throughput screening laboratory prepares crystal-growth screening experiments for a nominal fee, which can be waived for academic users under certain circumstances. Investigators are encouraged to contribute their data to the crystallization database being compiled as part of ongoing in the department.

Gross Anatomy Lab

The lab permits researchers and students to work with their cadaveric material for surgical training, and learning and reviewing human anatomy. It also loans models to educators, legal professionals and others for demonstrations.

Health Sciences Instrument Shops

The Health Science Instrument Shops provide instrument repair, custom equipment design and fabrication, instrument modification and instrument testing, calibration and diagnosis.

ResearchMatch

ResearchMatch is a national database that allows researchers to easily and quickly recruit the number and type of human volunteers needed for clinical trials and research studies. The free, secure registry is open to individuals with specific diseases as well as healthy volunteers. A detailed search can yield a pool of potential volunteers who meet all study criteria. The service also may be used to almost instantly test the feasibility of a study idea at no cost.

Toxicology Research Center

This multidisciplinary center conducts antimicrobial testing as well as studies on biodegradation and preclinical testing in support of new drug applications, particularly grain imaging agents. In addition to its ongoing research projects, the center’s equipment and expertise support university and industrial interests.

Supplies

Biochemistry Stockroom

Supplies the school and affiliated research programs with biochemical reagents.