Recent Faculty Publications
Our research has been published in a variety of national and international peer-reviewed journals.
- Battaglia MC, Bhalla M, Marzullo B, Betadpur A, Lenhard AP, Mohamed RH, Kalem MC, Heinzinger LR, Leus PA, Labarron S, Garrett-Sinha LA, Mecsas J, Blumental-Perry A, Bou Ghanem EN. (2026) Host Aging Induces a Senescent-Like Phenotype in Neutrophils and Altered Transcriptional Responses to Streptococcus pneumoniae. Aging cell (Mar), 25(3): e70435.
- Simmons SR, Rivera A, Bou Ghanem EN. (2026) Basal activation of ERK1/2 blunts the antimicrobial activity of neutrophils from old hosts against antibody-opsonized Streptococcus pneumoniae. Journal of leukocyte biology (Jan)
- Chak V, Bybel M, Harne S, Kay JG, Wohlfert E, Balu-Iyer SV. (2025) Phosphatidylserine exposure on tolerogenic nanoparticle correlate with oral tolerance. Scientific reports (Dec).
- Fletcher JR, Hansen LA, Hoyser JR, Hanna AE, Martinez R, Freeman CD, Thorns NT, Penningroth MR, Villarreal AR, Vogt GA, Tyler MA, Hines KM, Hunter RC. (2025) Commensal-derived short-chain fatty acids disrupt lipid membrane homeostasis in Staphylococcus aureus. mBio (Nov)e0139225.
- Arif SJ, Hoffman KM, Flynn JM, Wiggen TD, Lucas SK, Villarreal AR, Gilbertsen AJ, Dunitz JM, Hunter RC. (2025) Host- and microbial-mediated mucin degradation differentially shape Pseudomonas aeruginosa physiology and gene expression. PLoS pathogens (Oct), 21(10): e1013568.
- Huang YJ, Hunter RC. (2025) Community ecology: the framework for next steps in microbiome research in chronic airway disease. The European respiratory journal (Oct).
- Tchalla EYI, Betadpur A, Khalil AY, Lopez E, Bhalla M, Chang M, Wohlfert EA, Ghanem ENB. (2025) Neutrophils induce effective antibody responses to the pneumococcal conjugate vaccine by inhibiting regulatory T cells. bioRxiv : the preprint server for biology (Oct).
- Chak V, Ovalle EJ, Bard J, Wohlfert EA, Kay JG, Balu-Iyer S. (2025) Single-cell transcriptional analysis of murine mesenteric lymph nodes following oral lyso-phosphatidylserine nanoparticle administration reveals cellular heterogeneity in tolerance features. Journal of pharmaceutical sciences (Sep), 114(9): 103919.
- Bhalla M, Simmons SR, Lenhard A, Betadpur A, Battaglia MC, Bou Ghanem EN. (2025) Damage response signaling by the extracellular adenosine pathway: control of infection outcome during host aging. mSphere (Aug)e0064023.
- Lembke HK, Nauta KM, Hunter RC, Carlson EE. (2025) Evaluating the Link between Efflux Pump Expression and Motility Phenotypes in Pseudomonas aeruginosa Treated with Virulence Inhibitors. ACS infectious diseases (Aug), 11(8): 2080-2089.
- Recio-Balsells AI, Panozzo-Zénere E, Carlucci R, Chaurasia N, Manhas A, Fioressi MB, Montagna GN, Arrizabalaga G, Khan SI, Tekwani BL, Kumar N, Labadie GR. (2025) Advancing N,N'-disubstituted diamines in antimalarial drug development: Structure-activity relationships and mechanistic studies. European journal of medicinal chemistry (Jul), 291: 117630.
- Fletcher JR, Hunter RC. (2025) Cross-feeding interactions between Fusobacterium nucleatum and the glycan forager Segatella oris. bioRxiv : the preprint server for biology (Jun).
- Moore PJ, Hoffman K, Ahmed S, Fletcher JR, Wiggen TD, Lucas SK, Arif SJ, Gilbertsen AJ, Kent LA, Fiege JK, Langlois RA, O'Grady SM, Hunter RC. (2025) Dual oxic-anoxic co-culture enables direct study of anaerobe-host interactions at the airway epithelial interface. mBio (May), 16(5): e0133824.
- Simmons SR, Lenhard AP, Battaglia MC, Bou Ghanem EN. (2025) Adenosine 2B Receptor Signaling Impairs Vaccine-Mediated Protection Against Pneumococcal Infection in Young Hosts by Blunting Neutrophil Killing of Antibody-Opsonized Bacteria. Vaccines (Apr), 13(4) doi:10.3390/vaccines13040414
- Krueger A, Horjales S, Yang C, Blakely WJ, Francia ME, Arrizabalaga G. (2025) The essential kinase TgGSK regulates centrosome segregation and endodyogeny in Toxoplasma gondii. mSphere (Apr), 10(4): e0011125.
- Roach SN, Phillips W, Pross LM, Sanders AE, Pierson MJ, Hunter RC, Langlois RA. (2025) Virus-induced perturbations in the mouse microbiome are impacted by microbial experience. mSphere (Feb)e0056324.
- Waxman B, Salka K, Timilsina U, Umthong S, Shukla D, Stavrou S. (2025) Heparanase, a host gene that potently restricts retrovirus transcription. mBio (Feb)e0325224.
- Ciganda M, Jackson AP, Bangs JD. (2024) Diversification of sphingolipid synthase activities in kinetoplastid protozoa. Molecular and biochemical parasitology (Dec), 260: 111656.
- Sharif M, Greenberg L, Bangs J. (2024) Multifunctional Roles of Sec13 Paralogues in the Euglenozoan Trypanosoma brucei. bioRxiv : the preprint server for biology (Dec). doi:10.1101/2024.12.03.626618
- Heise N, Koeller CM, Sharif M, Bangs JD. (2024) Stage-specific function of sphingolipid synthases in African trypanosomes. mBio (Dec)e0350124.
