Tri-Institutional Research Day Showcases MD-PhD Students

Published January 9, 2020

story by bill bruton

Fifteen students in the MD-PhD program at the Jacobs School of Medicine and Biomedical Sciences presented posters at the Tri-Institutional MD-PhD Research Day last fall at the Jacobs School building in downtown Buffalo.

The event takes place in collaboration with the University of Rochester and SUNY Upstate Medical University, with the event rotating each year between the three schools.

Students Have Varied Research Interests

Jacobs School students, their programs and poster topics were:

  • Clayton Brady
    Physiology and Biophysics
    “Consequences of Impaired Bicarbonate Transport”
  • Kanita Chaudhry
    Immunology — Roswell Park Comprehensive Cancer Center
    “AhR-Mediated Regulation of Multiple Myeloma Survival”
  • Megan Conrow
    “Targeted Knockdown of the Autism-Linked Gene ADNP in Medial Prefrontal Cortex Induces Cognitive Dysfunction in Adolescent Mice”
  • James Cooper
    Pharmacology and Toxicology
    “Large Volume Demyelination in the Leporine CNS”
  • Tom Fuchs
    “Predictions From Structural Network Disruption and Default-Mode Network Functional Connectivity for Restorative Cognitive Rehabilitation Outcomes in Multiple Sclerosis”
  • Eric Irons
    Molecular and Cellular Biology — Roswell Park Comprehensive Cancer Center
    “Regulation of Hematopoiesis and Immune Cell Activation by an Extracellular Sialyltransferase”
  • Daniel S. Jaremko
    Microbiology and Immunology
    “Identifying Critical Interactions in the Unique Trypanosoma Brucei 5S Ribonucleoprotein Complex and Their Role in Ribosome Biogenesis”
  • Cameron MacDonald
    Immunology — Roswell Park Comprehensive Cancer Center
    “Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation”
  • Matthew McGuire
    “Modeling the Development of Post-Traumatic Epilepsy Following Severe Traumatic Brain Injury”
  • Chelsey B. Reed
    “Calcineurin in Myelination and Repair”
  • James C. Schuler
    Biomedical Informatics
    “Computational Drug Repurposing With CANDO”
  • Yuhao Shi
    Pharmacology and Therapeutics — Roswell Park Comprehensive Cancer Center
    “Intrinsic Tumor Cell Consequences of Acquired Resistance to PD-L1 Blockade”
  • Jiho Sohn
    Genetics, Genomics and Bioinformatics

    “The Potential Role of Periodontopathogens in Inflammatory Bowel Disease”
  • Alex Sunshine
    “The Transcription Factor Ets1 Cooperates With IL-17RA to Prevent Development of Autoimmunity and Immunodeficiency”
  • Nadav I. Weinstock
    “Conditional Knockout Model of Krabbe Disease”

Residency Directors Speak About Their Roles

A panel session titled “Tips From Residency Directors” featured six directors and the programs they lead:

The panel breakout for the session on “How to be a PI” consisted of the following faculty and their research specialty:

Alex Sunshine and Mary Gallo, a doctoral student in microbiology and immunology, were part of the panel breakout for “Transition and Success in M3/M4.”

Chelsey B. Reed and Nadav I. Weinstock were part of the panel breakout for “Applying for an F30.”

Tom Fuchs and James C. Schuler also gave talks on their research.

Expert on Gliomas Gives Keynote Speech

Keynote speaker Craig M. Horbinski, MD, PhD, professor of pathology/neurological surgery at Northwestern University Feinberg School of Medicine, spoke on “Maximizing Your Potential as a Physician-Scientist.”

Horbinski, a native of Buffalo, is a 2003 graduate of the MD-PhD program at UB.

He completed an anatomic pathology residency and a neuropathology fellowship at the University of Pittsburgh.

Horbinski directs the Nervous System Tumor Bank and the Mouse Histology and Phenotyping Laboratory at Northwestern, in addition to overseeing molecular diagnostics in gliomas.

He has authored more than 120 peer-reviewed publications and has obtained extramural research support as a principal investigator from multiple sources, including the National Institutes of Health. He has delivered more than 70 invited talks and platform presentations on gliomas in a variety of national and international settings.

Horbinski is an associate editor of Neuro-Oncology, and is on the editorial board of the top three neuropathology journals (Acta Neuropathologica, Brain Pathology and Journal of Neuropathology & Experimental Neurology).