This facility analyzes the engraftment of a variety of stem cells in vivo, the effects of genetic modification of stem cells on engraftment and stem cell function, and the behaviorial consequences of neural engraftment.

We provide:

• stereotaxic and other surgical engrafting of ESC, iPSC, ASC and cancer stem cells into mice and other model systems
• in vivo gene transfer into endogenous stem cells in brain, heart and other organs
  
• histochemical qualitative and quantitative stereological evaluation of stem cell survival, differentiation (morphological and biochemical) in vivo and in vivo integration of grafted or endogenous stem cells
• behavioral evaluation of stem cell therapy in animal models

431 Biomedical Research Building