Scott H. Stewart MD, MS
Scott H. Stewart
MD, MS
Associate Professor
Jacobs School of Medicine & Biomedical Sciences
Specialty/Research Focus
Internal Medicine
Professional Summary:
I am a member of the Division of General Internal Medicine, which consists of a team of dedicated professionals providing exceptional preventive care, acute care, and chronic disease management for adults across the entire spectrum of health and disease. I work closely with and supervise University at Buffalo students and residents in their care of patients at the Internal Medicine Center at ECMC and in the care of hospitalized patients at ECMC.
I am also engaged in research on alcoholism and alcohol-related disease, including the detection and treatment of these commonly encountered conditions in medical settings. Alcohol-related problems are often unrecognized due to a lack of specific diagnostic testing or simply not linking heavy drinking to problems that are not always or not usually alcohol-related (e.g., hypertension). If alcohol is recognized as a problem, tools to treat alcoholism have not typically been adapted for primary care nor have many physicians received specific training in managing alcoholism.
With the support of the National Institutes of Health and other organizations, I conduct cutting-edge research on the assessment and treatment of patients with alcohol-related disease using brief counseling methods and medications that are appropriate for primary care practices. I am also heavily involved in studying the use of novel laboratory tests for detecting unhealthy drinking patterns and alcohol-related organ damage.
My goal as a clinical researcher is to provide tools that enable physicians to provide care for alcohol-related disorders as they do for other chronic diseases such as diabetes and high cholesterol. This includes the use of laboratory tests to monitor control of the disease, guide the use of medications and brief counseling in busy medical settings, and determine the need for more intensive treatment or referral to addiction specialists.
Education and Training:
- MS, Clinical Research, Medical University of South Carolina (2001)
- Fellowship, General Internal Medicine and Health Services Research, Medical University of South Carolina (2001)
- Internship, Internal Medicine, University of Pittsburgh Medical Center (1996)
- MD, Medicine, Temple University (1993)
Employment:
- Associate Professor with tenure, Medicine, University at Buffalo (2012-present)
- Assistant Professor of Psychiatry and Medicine, Medicine, Medical University of South Carolina, Center for Drug & Alcohol Problems, College of Medicine (2006–2012)
- Assistant Professor of Medicine, Medicine, University at Buffalo (2001–2006)
- Academic Generalist Fellow, Medicine, Center for Health Services Research, Medical University of South Carolina (1999–2001)
- General Internist, Internal Medicine Associates, P.A. (1996–1999)
Research Expertise:
- Alcoholism and alcohol related disease: Detection of alcoholism and alcohol-related diseases in medical and surgical settings. Treatment of alcohol dependence using methods appropriate for primary care settings. Validation of biomarkers for unhealthy drinking and early alcohol-related disease. Clinical epidemiology of alcohol and alcohol-related disease.
Grants and Sponsored Research:
- January 2014–December 2015
Empire Clinical Research Investigator Program
NY State Department of Health
Role: Principal Investigator
$150,000 - September 2009–August 2013
Phosphatidylethanol as an alcohol biomarker in patients with liver disease (AA017911)
National Institute on Alcohol Abuse and Alcoholism (NIH)
Role: Principal Investigator - May 2004–April 2009
Alcohol Dependence in General Medical Settings (AA014188)
National Institute on Alcohol Abuse and Alcoholism (NIH)
Role: Principal Investigator
Journal Articles:
- Stewart SH, Koch DG, Willner IR, Anton RF, Reuben A. Validation of Blood Phosphatidylethanol as an Alcohol Consumption Biomarker in Patients with Chronic Liver Disease. Alcohol Clin Exp Res. 2014; 38(6).
- Stewart SH, Koch DG, Willner IR, Randall PK, Reuben A. Hair ethyl glucuronide is highly sensitive and specific for moderate to heavy drinking in patients with liver disease. Alcohol and Alcoholism. 2013; 48(1).
- Makdissi R Stewart SH. Care for hospitalized patients with unhealthy alcohol use: A narrative review. Addiction Science and Clinical Practice. 2013; 8(11).
- Stewart SH, Koch DG, Burgess DM, Willner IR, Reuben A. Sensitivity and specificity of urinary ethyl glucuronide and ethyl sulfate in liver disease patients. Alcoholism: Clinical and Experimental Research. 2013; 37(1).
- Book SW, Thomas SE, Stewart SH, Miller PM. Client attitudes toward alcohol self-report. Substance Abuse. 2012; 33(2).
- Miller PM, Book SW, Stewart SH. Medical treatment of alcohol dependence: a systematic review. International Journal of Psychiatry in Medicine. 2011; 42(3).
- Stewart SH, Borg KT, Miller PM. Prevalence of problem drinking and characteristics of a single question screen. Journal of Emergency Medicine. 2010; 39(3).
- Stewart SH, Doscher A, Miles S, Borg KT. Identification and risk stratification of problem drinkers with minor trauma. Western Journal of Emergency Medicine. 2010; 11(2).
- Stewart SH, Law TL, Randall PK, Newman R. Phosphatidylethanol and alcohol consumption in reproductive-age women. Alcoholism: Clinical and Experimental Research. 2010; 34(3).
- Stewart SH, Comte-Walters S, Bowen E, Anton RF. Liver disease and HPLC-quantification of disialotransferrin for heavy alcohol use: A case series. Alcoholism: Clinical and Experimental Research. 2010; 34(11).
- Stewart SH, Oroszi G, Randall PK, Anton RF. COMT genotype influences the effect of alcohol on blood pressure: Results from the COMBINE Study. American Journal of Hypertension. 2009; 22(1).
- Stewart SH, Reuben A, Brzezinski WA, Koch DG, Basile J, Randall PK, Miller PM. Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. Alcohol and Alcoholism. 2009; 44(5).
- Anton RF, Randall PK, Myrick L, Latham PK, Baros A, Stewart SH, Malcolm RJ. Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: Relationship to alcohol withdrawal symptoms. Journal of Clinical Psychopharmacology. 2009; 29(4).
- Stewart SH, Latham PK, Randall P, Miller PM, Anton RF. Blood pressure reduction during treatment for alcohol dependence: Results from the COMBINE Study. Addiction. 2008; 103.
- Stewart SH, Connors GJ. Ethnicity, alcohol drinking and changes in transaminase activity among heavy drinkers. J Natl Med Assoc. 2007; 99(5).
- Stewart SH, Connors GJ, Hutson AD. Ethnicity and gamma-glutamyltransferase in men and women with alcohol use disorders. Alcohol & Alcoholism. 2007; 42(1).
- Stewart SH, Connors GJ. Interest in pharmacotherapy and primary care alcoholism treatment among medically hospitalized, alcohol dependent patients. Journal of Addictive Diseases. 2007.
- Stewart SH. Alcoholics in acute medical settings have increased risk for other drug, mood, and personality disorders. International Journal of Psychiatry in Medicine. 2007; 37(1).
- Stewart SH, Miller PM. Detecting alcohol use disorders in persons with recent hospitalization: an analysis of the National Epidemiologic Survey on Alcohol and Related Conditions. Journal of Addiction Medicine. 2007; 1(1).
- Stewart SH, Connors GJ. Perceived health status, alcohol-related problems, and readiness to change among medically hospitalized alcohol dependent patients. Journal of Hospital Medicine. 2007; 2(6).
- Janicki TA, Stewart SH. Stress ulcer prophylaxis for general medical patients: a review of the evidence. Journal of Hospital Medicine. 2007; 2(2).
- Stewart SH, Miller PM. Detection and treatment of alcohol-sensitive hypertension. Current Hypertension Reviews. 2007; 3.
- Stewart SH, Hutson AD, Connors GJ. Exploring the relationship between drinking intensity and quality of life. American Journal on Addictions. 2006; 15(5).
- Stewart SH, Connors GJ. Screening for alcohol problems. What makes a test effective?. Alcohol Research and Health. 2005; 28(1).
- Stewart S. Patterns of Alcohol Use and Cardiovascular Risk Factors in the US Population. Alcohol Research. 2003; 8(3).
- Stewart SH, Stewart S. Alcohol use and cardiovascular disease preventive services. J Cardiovasc Risk. 2003; 10(3).
- Stewart SH, Stewart S. Racial and ethnic differences in alcohol-associated aspartate aminotransferaseand gamma-glutamyltransferase elevation. Arch Intern Med. 2002; 162(19).
- Stewart SH, Stewart S. Alcohol and inflammation: a possible mechanism for protection against ischemicheart disease. Nutr Metab Cardiovasc Dis. 2002; 12(3).
- Stewart SH, Silverstein MD. Racial and ethnic disparity in blood pressure and cholesterol measurement. J Gen Intern Med. 2002; 17(6).
- Stewart S, Mainous AG, Gilbert G. Relation between alcohol consumption and C-reactive protein in the adult US population. Journal of the American Board of Family Practice. 2002; 15(6).
Books and Book Chapters:
- Stewart SH, Goldmann A, Neumann T, Spies C.. Biomarkers of alcohol and other drug use. 2010.
- Stewart SH. Dependence and diagnosis. 2009.
- Stewart SH, Miller PM. Alcohol screening and intervention in medical and surgical settings. 2007.
- Stewart SH. Alcoholism, substance abuse, and prescription drug abuse. 2004.
Professional Memberships:
- American College of Physicians
- Research Society on Alcoholism
- International Society for Biomedical Research on Alcoholism
- Society of General Internal Medicine
- American Society of Addiction Medicine
Presentations:
- "Unhealthy Alcohol Use in Hospitalized Patients" Mercy Hospital of Buffalo Saturday CME Series (2014)
- "Phosphatidylethanol vs. Ethyl Glucuronide in Patients with Liver Disease" Research Society on Alcoholism (2013)
- "Alcohol use and hospitalization: Patterns and relapse prevention" Grand Rounds, Buffalo General Hospital, Department of Medicine (2013)
- "Unhealthy Alcohol Use in Hospitalized Patients" City-Wide Grand Rounds, University at Buffalo, Department of Medicine (2013)
- "Testing for heavy drinking" Medical Section, American Council of Life Insurers (2012)
- "Novel Alcohol Consumption Biomarkers" Grand Rounds, Dept. of Psychiatry, Georgia Health Sciences University, Georgia Health Sciences University, Department of Psychiatry (2011)
- "Novel Alcohol Consumption Biomarkers" Grand Rounds, Dept. of Psychiatry, Medical University of South Carolina, MUSC, Dept. of Psychiatry (2010)
- "Liver disease and estimation of % disialotransferrin" Research Society on Alcoholism (2010)
- "Alcohol consumption biomarkers for assessment and risk assessment" Research Society on Alcoholism (2008)
- "Alcohol biomarkers" Team on underage drinking research, NIH, NIAAA (NIH) (2007)
- "Interest in pharmacotherapy and primary care treatment among medically hospitalized, alcohol dependent patients" Research Society on Alcoholism (2006)
- "Relationships between drinking and quality of life indicators" Research Society on Alcoholism (2005)
- "Alcohol and C-Reactive Protein" Grand Rounds, Department of Medicine, Erie County Medical Center, Erie County Medical Center, Dept. of Medicine (2004)
- "Association between alcohol consumption and C-reactive protein: Importance of lifetime abstinence" Research Society on Alcoholism (2004)
- "Alcohol use and primary care utilization" Research Society on Alcoholism (2003)
Service Activities:
- Editoral board, Addiction Science and Clinical Practice; Editorial Board Member (2010–present)
- Field reviewer, SAMHSA Treatment Improvement Protocol Series 49; Reviewer (2009)
- Editorial Consultant, Alcohol abuse module, Physicians' Information and Education Resource, American College of Physicians; Consultant (2007–2010)
- Peer review, > 20 professional journals; Peer Reviewer (2001–present)