Recent Faculty Publications

Our contributions to the scholarly literature demonstrate our commitment to advancing the field of biomedical informatics.

Schuler J, Falls Z, Mangione W, Hudson ML, Bruggemann L, Samudrala R. (2022) Evaluating the performance of drug-repurposing technologies. Drug discovery today (Jan), 27(1): 49-64.
Schuler J, Falls Z, Mangione W, Hudson ML, Bruggemann L, Samudrala R. (2022) Evaluating the performance of drug-repurposing technologies. Drug discovery today (Jan), 27(1): 49-64.
Overhoff B, Falls Z, Mangione W, Samudrala R. (2021) A Deep-Learning Proteomic-Scale Approach for Drug Design. Pharmaceuticals (Basel, Switzerland) (Dec), 14(12). doi:10.3390/ph14121277
Overhoff B, Falls Z, Mangione W, Samudrala R. (2021) A Deep-Learning Proteomic-Scale Approach for Drug Design. Pharmaceuticals (Basel, Switzerland) (Dec), 14(12). doi:10.3390/ph14121277
Dey-Rao R, Smith GR, Timilsina U, Falls Z, Samudrala R, Stavrou S, Melendy T. (2021) A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition. Antiviral research (Nov), 195: 105183. doi:10.1016/j.antiviral.2021.105183
Dey-Rao R, Smith GR, Timilsina U, Falls Z, Samudrala R, Stavrou S, Melendy T. (2021) A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition. Antiviral research (Nov), 195: 105183. doi:10.1016/j.antiviral.2021.105183
Chatrikhi R, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S, Brennessel WW, Jenkins JL, Walter MJ, Graubert TA, Samudrala R, Jurica MS, Frontier AJ, Kielkopf CL. (2021) A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex. Cell chemical biology (Aug), 28(8): 1145-1157.e6. doi:10.1016/j.chembiol.2021.02.007
Chatrikhi R, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S, Brennessel WW, Jenkins JL, Walter MJ, Graubert TA, Samudrala R, Jurica MS, Frontier AJ, Kielkopf CL. (2021) A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex. Cell chemical biology (Aug), 28(8): 1145-1157.e6. doi:10.1016/j.chembiol.2021.02.007
Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, Maity D, Ali L, Kalmouni M, Hunashal Y, Ahmed J, Houhou T, Karapetyan S, Falls Z, Samudrala R, Pasricha R, Esposito G, Afzal AJ, Hamilton AD, Kumar S, Magzoub M. (2021) Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. Nature communications (Jun), 12(1): 3962. doi:10.1038/s41467-021-23985-1
Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, Maity D, Ali L, Kalmouni M, Hunashal Y, Ahmed J, Houhou T, Karapetyan S, Falls Z, Samudrala R, Pasricha R, Esposito G, Afzal AJ, Hamilton AD, Kumar S, Magzoub M. (2021) Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. Nature communications (Jun), 12(1): 3962. doi:10.1038/s41467-021-23985-1
Hudson ML, Samudrala R. (2021) Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform. Molecules (Basel, Switzerland) (Apr), 26(9). doi:10.3390/molecules26092581
Falls Z, Fine J, Chopra G, Samudrala R. (2021) Accurate Prediction of Inhibitor Binding to HIV-1 Protease Using CANDOCK. Frontiers in chemistry (Jan), 9: 775513. doi:10.3389/fchem.2021.775513
Falls Z, Fine J, Chopra G, Samudrala R. (2021) Accurate Prediction of Inhibitor Binding to HIV-1 Protease Using CANDOCK. Frontiers in chemistry (Jan), 9: 775513. doi:10.3389/fchem.2021.775513
Mangione W, Falls Z, Chopra G, Samudrala R. (2020) cando.py: Open Source Software for Predictive Bioanalytics of Large Scale Drug-Protein-Disease Data. Journal of chemical information and modeling (Sep), 60(9): 4131-4136. doi:10.1021/acs.jcim.0c00110
Mangione W, Falls Z, Chopra G, Samudrala R. (2020) cando.py: Open Source Software for Predictive Bioanalytics of Large Scale Drug-Protein-Disease Data. Journal of chemical information and modeling (Sep), 60(9): 4131-4136. doi:10.1021/acs.jcim.0c00110
Pengput A, Schwartz DG. (2020) Risk Factors for Opisthorchis Viverrini Infection: A Systematic Review. J Infect Public Health (Sep), 13(9): 1265-1273.
Schwartz DG, McGrath SP, Monsen KA, Dixon BE. (2020) Current Approaches and Trends in Graduate Public Health Informatics Education in the United States: Four Case Studies from the Field. Online J Public Health Inform (Jul), 12(1): 7-7.
Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R. (2020) Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. Drug discovery today (Jul), 25(7): 1126-1128. doi:10.1016/j.drudis.2020.05.002
Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R. (2020) Letter to the Editor. Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. Drug discovery today (Jul), 25(7): 1126-1128. doi:10.1016/j.drudis.2020.05.002
Mandloi S, Falls Z, Deng R, Samudrala R, Elkin PL. (2020) Association of C>U RNA Editing with Human Disease Variants. Studies in health technology and informatics (Jun), 270: 1205-1206.

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