Mechanisms of functional and structural cardiac remodeling in heart disease, as well as novel therapeutic approaches to prevent or reverse left ventricular dysfunction caused by myocardial injury
Bisseling Q, Parker MD, Kerst S, Pasternack RA, Tondreau J, Breur M, van Rooijen-van Leeuwen GM, Tonduti D, Salsano E, Darling A, van Wijk JAE, Törnroth-Horsefield S, Bugiani M, Pouwels PJW, Waisfisz Q, van der Knaap MS, Min R. (2026) A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema. Annals of clinical and translational neurology (Mar).
Mechanisms of Heat Sensing by Nociceptive Vanilloid Receptors (Award 106744). Feng Qin (Principal Investigator). NIH. $2,178,335. 8/1/2026-8/1/2030.
Role of cardiac clock misalignment in promoting arrhythmias in swine and donor human hearts. Kedar Aras (Principal Investigator). NHLBI. $2,500,000. 6/1/2025-4/1/2030.
Cholinergic modulation of higher-order thalamus and perception. Garrett Neske (Principal Investigator). Whitehall Foundation. $300,000. 1/1/2026-12/1/2028.