Supports basic and clinical research related to the cause,
prevention and treatment of myelin-related diseases, such as Krabbe
and other leukodystrophies, multiple sclerosis and hereditary
An integrated academic home for UB’s outstanding clinical
research and translational science, and the hub of the Buffalo
Translational Consortium. The CTRC provides innovative research
tools, support, training, resources and coordination.
Kosman, PhD, studies how organisms acquire and metabolize iron
and copper, intrinsically toxic metals essential to cellular
respiration and oxygen transport. One of his goals is to develop
antifungal drugs to treat infections in humans.
Patel, PhD, is a specialist in nutritional biochemistry. He
found that fetuses of obese mother rats were programmed in utero to
develop obesity in adulthood, and was the first to show that this
metabolic programming occurs in the fetal hypothalamus.
Garrick, PhD, identified the first protein essential for normal
intestinal iron absorption and the first mammalian iron transporter
to be characterized at the molecular level. His work provides a
major step forward in the understanding of iron metabolism.
Popescu, PhD, is studying NMDA receptors in the brain, which
are involved in synaptic development, plasticity, memory and
learning, as well as in pathologies such as stroke,
neurodegeneration, chronic pain, addiction, schizophrenia and
Lee, PhD, demonstrated for the first time, in an animal model,
that injecting adult bone marrow stem cells into skeletal muscle
can repair cardiac tissue, reversing heart failure. He and his team
showed that this non-invasive procedure increased heart cells