Recent Research Funding

Our faculty secure major research grants from various National Institutes of Health as well as private sources.

Jonathan Bard, PhD

  • Therapeutic targeting of master regulators in non-canonical AR driven advanced lethal prostate cancers. Jonathan Bard (Co-Investigator). NCI. $3,823,553. 8/1/2023-7/1/2028.
  • Cell Type Specific Activation of Endoplasmic Reticulum Sensor, ATF6, Drives Fibrotic Remodeling in Pericytes and SMC. Jonathan Bard (Co-Investigator). American Heart Association. $300,000. 7/1/2025-6/1/2028.
  • Impact of Sex on Mitochondrial and Epigenetic Mechanisms in Age-Related Macular Degeneration. Jonathan Bard (Co-Investigator). National Institutes of Health. $2,231,306. 4/1/2025-3/1/2029.
  • Regulatory Mechanisms in Salivary Gland Development and Regeneration. Jonathan Bard (Co-Investigator). NIDCR. $3,743,537. 7/1/2024-6/1/2029.

Sarah Bowman, PhD

  • National HTX Center: Enabling Access to State-of-the-Art Crystallization Capabilities. Sarah Bowman (Principal Investigator). National Institutes of Health. $4,910,000. 7/1/2021-6/1/2026.
  • New techniques for detecting and handling nanocrystals for cutting edge structural biology methods. Sarah Bowman (Principal Investigator). NIH. $1,570,000. 9/1/2022-8/1/2026.
  • Acquisition of an SPT Labtech Mosquito Administrative Supplement. Sarah Bowman (Principal Investigator). NIH. $167,746. 8/1/2025-9/1/2026.
  • Probing evolutionary pathways in metalloprotein structure and function from emerging bacterial pathogens. Sarah Bowman (Principal Investigator). University at Buffalo Bridge Funding Opportunity-UB LAUNCH & Department of Biochemistry. $50,000. 11/1/2025-8/1/2026.
  • Studying structure and function of bacterial proteins using structural biology and enzymatic assays. Sarah Bowman (Principal Investigator). University at Buffalo Undergraduate Research and Creative Activities Program. $15,500. 1/1/2026-12/1/2026.

Michael Buck, PhD

  • Genomic and epigenomic investigations of the transcriptional regulatory network of skin keratinocytes in defined genetic models. Michael Buck (Co-Investigator). NIH. $1,754,500. 3/1/2018-1/1/2024.
  • Protective effects of dietary pulse flours on the transgenerational influence of maternal obesity. Michael Buck (Co-Investigator). United States Department of Agriculture. $480,255. 9/1/2020-2/1/2024.
  • Therapeutic targeting of master regulators in non-canonical AR driven advanced lethal prostate cancers. Michael Buck (Co-Investigator). NCI. $3,823,553. 8/1/2023-7/1/2028.

Rebekah Charney, PhD

  • Examining neurological disability in Mowat-Wilson syndrome using brain organoids. Rebekah Charney (Principal Investigator). The Mowat-Wilson Syndrome Foundation. 7/1/2022-6/1/2025.
  • The role of the transcriptional repressor ZEB2 in human neural crest cell formation and craniofacial pathology. Rebekah Charney (Principal Investigator). NIH-NIDCR R00. 9/1/2024-8/1/2027.

Dahong Chen, PhD

  • Chromatin architectural factor-mediated epigenetic regulation of neuronal remodeling during development. Dahong Chen (Principal Investigator). NIH. 1/1/2024-1/1/2027.

D. Fernando Estrada, PhD

  • Structural regulation in mitochondrial vitamin-D and vitamin-A metabolizing cytochromes P450. D. Fernando Estrada (Principal Investigator). National Institute of General Medical Sciences. $1,987,200. 9/1/2019-8/1/2024.
  • Impact of Pseudomonas aeruginosa cytochrome P450 enzymes and secondary metabolites on drug metabolism and disposition in the cystic fibrosis patient. D. Fernando Estrada (Co-Principal Investigator). NIAID. $632,183. 1/1/2024-1/1/2028.
  • Noncompetitive inhibition of CYP121 dimers of Mycobacterium tuberculosis. D. Fernando Estrada (Principal Investigator). NIAID. $442,750. 7/1/2024-7/1/2026.

Marc Halfon, PhD

  • Mechanisms of Gene Regulatory Network Evolution. Marc Halfon (Principal Investigator). NSF. $1,106,456. 9/1/2019-8/1/2024.
  • Regulatory Element Discovery in Sequenced Insect Species. Marc Halfon (Principal Investigator). USDA. $445,911. 6/1/2019-5/1/2023.
  • REDfly: The regulatory element database for Drosophila and other insects. Marc Halfon (Principal Investigator). NIH/NIGMS. $1,415,154. 9/1/2021-8/1/2025.
  • Measuring functional similarity between transcriptional enhancers using deep learning. Marc Halfon (Co-Investigator). NIH/NHGRI. $118,818. 9/1/2021-8/1/2024.

Daniel Kosman, PhD

  • Ferroportin and APP: Regulation of Iron Trafficking at the Blood-Brain Barrier. Daniel Kosman (Principal Investigator). NIDDS. $1,955,930. 8/1/2017-5/1/2024.
  • Molecular mechanisms of small molecule iron chelating antioxidants. Daniel Kosman (Principal Investigator). Alterity Therapeutics Annual MRSA 2020-2023 Dollar amount below for 2023. $253,573. 1/1/2020-7/1/2025.

Techung Lee, PhD

  • Poly(I:C) Drug Repurposing and SFRP-2 Gene Therapy in Tooth Regeneration. Techung Lee (Co-Principal Investigator). Robert Wood Johnson Foundation. $470,400. 2/1/2024-1/1/2028.

Norma Nowak, PhD

  • The Metagenomics Education Partnership. Norma Nowak (Co-Investigator). NIH/NIGMS. $1,288,542. 6/1/2020-4/1/2026.
  • Genomic surveillance of SARS-CoV-2 in Western New York. Norma Nowak (Co-Investigator). NYSDOH. $2,000,000. 10/1/2021-6/1/2025.
  • Personalizing Head and Neck Squamous Cell Carcinoma (HNSCC). Norma Nowak (Principal Investigator). Community Foundation of Greater Buffalo. $22,380. 12/1/2023-12/1/2024.
  • CRSC: ThermoFisher-GBC project. Norma Nowak (Principal Investigator). ThermoFisher Scientific. 1/1/2018-12/1/2026.
  • CRSC: ThermoFisher GBC project. Norma Nowak (Principal Investigator). ThermoFisher Scientific. $40,455. 1/1/2018-12/1/2026.
  • Human miRNA Sequencing. Norma Nowak (Principal Investigator). VA. $183,213. 9/1/2023-9/1/2028.

Yungki Park, PhD

  • Modulation of oligodendrocyte development by voltage-operated calcium channels. Yungki Park (Co-Investigator). NIH. $1,993,750. 12/1/2021-11/1/2026.
  • Elucidating the role of Nucks1 in Myrf expression and central nervous system myelination. Yungki Park (Principal Investigator). UB Neuroscience. $40,000. 10/1/2024-12/1/2025.
  • Systematic discovery of Olig2 upstream regulators for central nervous system myelination. Yungki Park (Principal Investigator). NIH. $440,275. 7/1/2025-6/1/2027.
  • Genomic and functional investigations of the transcriptional regulatory network of tooth enamel development. Yungki Park (Co-Investigator). NIH. $1,956,180. 7/1/2023-6/1/2028.

Mulchand Patel, PhD

  • Protective effects of dietary pulse flours on the transgenerational influence of maternal obesity. Mulchand Patel (Co-Investigator). USDA-National Institute of Food and Agriculture. $480,255. 9/1/2020-9/1/2023.
  • Alpha Lipoic acid as maternal supplement in obese pregnancies. Mulchand Patel (Co-Principal Investigator). NIH, National Center for Complementary and Integrative Health. $438,625. 2/1/2022-1/1/2024.
  • Protective mechanisms of pulse crop consumption in the development of non-alcoholic fatty liver disease in mothers and offspring across life stages. Mulchand Patel (Co-Principal Investigator). USDA, USDA Pulse Crop Health Initiative. $421,744. 8/1/2023-7/1/2026.

Gabriela Popescu, PhD

  • Experience-Dependent Reorganization of Excitatory Synapse Connectivity. Gabriela Popescu (Co-Principal Investigator). NIH/NIMH/R01. $3,270,000. 4/1/2019-4/1/2026.
  • CTSA UM1 State University of New York at Buffalo. Gabriela Popescu (Co-Investigator). National Center for Advancing Translational Sciences. $3,710,000. 1/1/2025-1/1/2031.

Christine Schaner Tooley, PhD

  • Expanding the Biological Roles of N-terminal methylation. Christine Schaner Tooley (Principal Investigator). NIGMS. $1,978,690. 1/1/2022-12/1/2026.

Satrajit Sinha, PhD

  • Genomic and epigenomic investigations of the transcriptional regulatory network of skin keratinocytes in defined genetic models. Satrajit Sinha (Principal Investigator). NIAMS. 3/1/2018-12/1/2023.
  • Genomic and functional investigations of the transcriptional regulatory network of salivary gland morphogenesis and stem cell fate choices in defined genetic models. Satrajit Sinha (Co-Principal Investigator). NIDCR. 3/1/2018-2/1/2024.
  • High resolution genomic and epigenomic mapping of the human salivary gland. Satrajit Sinha (Principal Investigator). NIH. $440,922. 8/1/2023-7/1/2025.
  • Genomic and functional investigations of the transcriptional regulatory network of tooth enamel development. Satrajit Sinha (Co-Investigator). NIH. $627,934. 7/1/2023-6/1/2028.

Jennifer Surtees, PhD

  • Genomic surveillance of SARS-CoV-2 in Western New York. Jennifer Surtees (Principal Investigator). New York State Department of Health `. $5,700,000. 9/1/2021-7/1/2026.
  • Integrated Ecosystems for Pandemic Prevention. Jennifer Surtees (Principal Investigator). NSF. $1,000,000. 9/1/2022-2/1/2026.
  • Role of Msh2-Msh3 in determining outcomes in pathways of DNA metabolism. Jennifer Surtees (Principal Investigator). National Science Foundation. $400,000. 9/1/2023-8/1/2027.
  • Characterizing the role of Elevated dNTP pools in sensitizing the replisome. Jennifer Surtees (Principal Investigator). NIGMS. $2,448,745. 9/1/2024-6/1/2029.

Mark Sutton, PhD

  • Coordination of High Fidelity Replication with Mutagenic Translesion Synthesis. Mark Sutton (Principal Investigator). NIH/GMS. $1,414,219. 2/1/2019-11/1/2024.
  • Novel Combination Therapies to Combat Hypermutable Carbapenem-Resistant P. aeruginosa. Mark Sutton (Co-Principal Investigator). NIH, NIAID. $3,850,992. 5/1/2022-4/1/2027.

Mary Taub, PhD

  • Regulation of the Kidney Cancer Epigenome by Oncometabolite L-2-Hydroxyglutarate. Mary Taub (Co-Principal Investigator). NCI. $372,110. 7/1/2016-7/1/2023.