Recent Faculty Publications
Bogdan Beirowski, MD, PhD
Michael Buck, PhD
- Hu Z, Li H, Jiang H, Ren Y, Yu X, Qiu J, Stablewski AB, Zhang B, Buck MJ, Feng J, Buck M. (2020) Transient inhibition of mTOR in human pluripotent stem cells enables robust formation of mouse-human chimeric embryos. Sci Adv (May), 6(20): 0298-0298.
- Yu X, Buck MJ, Buck M. (2020) Pioneer factors and their in vitro identification methods. Mol Genet Genomics (Apr).
- Tsompana M, Gluck C, Sethi I, Joshi I, Bard J, Nowak NJ, Sinha S, Buck MJ, Buck M. (2020) Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma. Oncogene (Jan), 39(2): 262-277.
D. Fernando Estrada, PhD
- Kumar A, Campomizzi CS, Jay N, Ferguson S, Scheffler EJ, Lioi J, Tu C, Qu J, Simons C, Estrada DF. (2021) Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis. Scientific reports (Jan), 11(1): 394. doi:10.1038/s41598-020-79545-y
- Kumar A, Wilderman PR, Tu C, Shen S, Qu J, Estrada DF, Estrada D. (2020) Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1. Biochemistry (Apr), 59(15)
- Kumar A, Estrada DF, Estrada D. (2019) Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate. Drug Metab Dispos (Jan), 47(9)
M. Laura Feltri, MD
- N.I. Weinstock*, D. Shin*, N. Dhimal, X. Hong, E. E. Irons, N. Silvestri, C.B. Reed, D. Nguyen, O. Sampson, Y.C. Cheng, J.T.Y. Lau, E. Bongarzone, J. Kofler, M. Escolar, M. Gelb, L. Wrabetz, M.L. Feltri. (2020) Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. Neuron (Jul), 107(1): 65-81.
- Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L, Feltri M. (2019) Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Hum Mol Genet (Jan).
Michael Garrick, PhD
- Wang X, Zhang M, Flores SRL, Woloshun RR, Yang C, Yin L, Xiang P, Xu X, Garrick MD, Vidyasagar S, Merlin D, Collins JF. (2019) Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis. Mol Ther (Mar), 27(3): 493-506.
Marc Halfon, PhD
- Schember I, Halfon MS. (2021) Identification of new Anopheles gambiae transcriptional enhancers using a cross-species prediction approach. Insect molecular biology (Apr).
- Nowling RJ, Behura SK, Halfon MS, Emrich SJ, Duman-Scheel M. (2021) PeakMatcher facilitates updated Aedes aegypti embryonic cis-regulatory element map. Hereditas (Jan), 158(1): 7. doi:10.1186/s41065-021-00172-2
- Sinha S, Jones BM, Traniello IM, Bukhari SA, Halfon MS, Hofmann HA, Huang S, Katz PS, Keagy J, Lynch VJ, Sokolowski MB, Stubbs LJ, Tabe-Bordbar S, Wolfner MF, Robinson GE. (2020) Behavior-related gene regulatory networks: A new level of organization in the brain. Proceedings of the National Academy of Sciences of the United States of America (Sep), 117(38): 23270-23279. doi:10.1073/pnas.1921625117
Daniel Kosman, PhD
Techung Lee, PhD
Norma Nowak, PhD
- Tsompana M, Gluck C, Sethi I, Joshi I, Bard J, Nowak NJ, Sinha S, Buck MJ, Buck M. (2020) Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma. Oncogene (Jan), 39(2): 262-277.
- Shen H, Yang N, Truskinovsky A, Chen Y, Mussell AL, Nowak NJ, Kobzik L, Frangou C, Zhang J. (2019) Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis. Mol Cancer Res (Jan), 17(1): 250-262.
Yungki Park, PhD
- Wang W, Cho H, Kim D, Park Y, Moon JH, Lim SJ, Yoon SM, McCane M, Aicher SA, Kim S, Emery B, Lee JW, Lee S, Park Y, Lee SK. (2020) PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. Cell Reports (Sep), 32(11): 108147.
- Jiang K, Kessler H, Park Y, Sudman M, Thompson SD, Jarvis JN. (2020) Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within JIA-associated risk loci. PLoS One (Jul), 15(7): e0235857.
- An H, Fan C, Sharif M, Kim D, Poitelon Y, Park Y. (2020) Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects. Scientific Reports (Jan), 10(1): 814.
Mulchand Patel, PhD
- Dumolt JH, Patel MS, Rideout TC. (2021) Excessive early-life cholesterol exposure may have later-life consequences for nonalcoholic fatty liver disease. Journal of developmental origins of health and disease (Apr), 12(2): 229-236. doi:10.1017/S2040174420000239
- Patel MS, Mahmood S, Jung J, Rideout TC. (2021) Reprogramming of aerobic glycolysis in non-transformed mouse liver with pyruvate dehydrogenase complex deficiency. Physiological reports (Jan), 9(1): e14684. doi:10.14814/phy2.14684
- Freedman D, Klejbor I, Mahmood S, Patel M, Stachowiak MK, Stachowiak EK. (2020) Loss of Oligodendrocytes in Mouse Model of Pyruvate Dehydrogenase Complex Deficiency and Partial Reversal by Phenylbutyrate Treatment.
Gabriela Popescu, PhD
Satrajit Sinha, PhD
- Oyelakin A, Horeth E, Song EC, Min S, Che M, Marzullo B, Lessard CJ, Rasmussen A, Radfar L, Scofield RH, Lewis DM, Stone DU, Grundahl K, De Rossi SS, Kurago Z, Farris AD, Sivils KL, Sinha S, Kramer JM, Romano RA. (2021) Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjogren‘s Syndrome. Front Immunol (Jan), 11: 606268-606268.
- Oyelakin A, Horeth E, Song EC, Min S, Che M, Marzullo B, Lessard CJ, Rasmussen A, Radfar L, Scofield RH, Lewis DM, Stone DU, Grundahl K, De Rossi SS, Kurago Z, Farris AD, Sivils KL, Sinha S, Kramer JM, Romano RA, Romano R. (2021) Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren‘s Syndrome. Front Immunol (Jan), 11: 606268-606268.
- Min S, Oyelakin A, Gluck C, Bard JE, Song EC, Smalley K, Che M, Flores E, Sinha S, Romano RA, Romano R. (2020) p63 and Its Target Follistatin Maintain Salivary Gland Stem/Progenitor Cell Function through TGF-B/Activin Signaling. iScience (Sep), 23(9): 101524-101524.
Jennifer Surtees, PhD
- Surtees JA, Russo T, Burnidge, AH. (2020) Mutation and Migration: Understanding and interpreting the meaning in our genomes. Perspectives from Biochemistry, Genetics, Infectious Disease and Dance. Transforming Global Health: Interdisciplinary Challenges, Perspectives, and Strategies (Jan)213-228.
- Williams GM, Petrides AK, Balakrishnan L, Surtees JA. (2020) Tracking expansions of stable and threshold length trinucleotide repeat tracts in vivo and in vitro using Saccahromyces cerevisiae. Methods in Molecular Biology (Jan), 2056: 25-68.
- Subramaniam R, Lamb NA, Hwang Y, Johengen L, Surtees JA. (2019) Extracting and Measuring dNTP Pools in Saccharomyces cerevisiae. Methods Mol Biol (Jan), 1999: 103-127.
Mark Sutton, PhD
- Homiski C, Scotland MK, Babu VMP, Chodavarapu S, Maul RW, Kaguni JM, Sutton MD. (2021) The mutant ßE202K sliding clamp protein impairs DNA polymerase III replication activity. Journal of bacteriology (Sep)JB0030321.
- Babu VMP, Homiski C, Scotland MK, Chodavarapu S, Kaguni JM, Sutton MD. (2021) Elevated levels of the E. coli nrdAB-encoded ribonucleotide reductase counteract the toxicity caused by an increased abundance of the ß clamp. Journal of bacteriology (Sep)JB0030421.
- Crane JK, Alvarado CL, Sutton MD. (2021) Role of the SOS Response in the Generation of Antibiotic Resistance In Vivo. Antimicrobial agents and chemotherapy (Jun), 65(7): e0001321.
