Recent Faculty Publications
Bogdan Beirowski, MD, PhD
- Babetto E, Wong KM, Beirowski B. (2021) Publisher Correction: A glycolytic shift in Schwann cells supports injured axons.
- Babetto E, Wong KM, Beirowski B. (2020) A glycolytic shift in Schwann cells supports injured axons. Nature neuroscience (Oct), 23(10): 1215-1228.
- Beirowski B. (2020) Measuring Bioenergetic Signatures of Peripheral Nerve Segments by Extracellular Flux Analysis. Methods in molecular biology (Clifton, N.J.) (Jan), 2143: 191-203.
Michael Buck, PhD
- Hu Z, Li H, Jiang H, Ren Y, Yu X, Qiu J, Stablewski AB, Zhang B, Buck MJ, Feng J, Buck M. (2020) Transient inhibition of mTOR in human pluripotent stem cells enables robust formation of mouse-human chimeric embryos. Sci Adv (May), 6(20): 0298-0298.
- Yu X, Buck MJ, Buck M. (2020) Pioneer factors and their in vitro identification methods. Mol Genet Genomics (Apr).
- Tsompana M, Gluck C, Sethi I, Joshi I, Bard J, Nowak NJ, Sinha S, Buck MJ, Buck M. (2020) Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma. Oncogene (Jan), 39(2): 262-277.
D. Fernando Estrada, PhD
- Kumar A, Campomizzi CS, Jay N, Ferguson S, Scheffler EJ, Lioi J, Tu C, Qu J, Simons C, Estrada DF. (2021) Surface hydrophobics mediate functional dimerization of CYP121A1 of Mycobacterium tuberculosis. Scientific reports (Jan), 11(1): 394. doi:10.1038/s41598-020-79545-y
- Kumar A, Wilderman PR, Tu C, Shen S, Qu J, Estrada DF, Estrada D. (2020) Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1. Biochemistry (Apr), 59(15)
- Kumar A, Estrada DF, Estrada D. (2019) Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate. Drug Metab Dispos (Jan), 47(9)
M. Laura Feltri, MD
- N.I. Weinstock*, D. Shin*, N. Dhimal, X. Hong, E. E. Irons, N. Silvestri, C.B. Reed, D. Nguyen, O. Sampson, Y.C. Cheng, J.T.Y. Lau, E. Bongarzone, J. Kofler, M. Escolar, M. Gelb, L. Wrabetz, M.L. Feltri. (2020) Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. Neuron (Jul), 107(1): 65-81.
- Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L, Feltri M. (2019) Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Hum Mol Genet (Jan).
Michael Garrick, PhD
- Wang X, Zhang M, Flores SRL, Woloshun RR, Yang C, Yin L, Xiang P, Xu X, Garrick MD, Vidyasagar S, Merlin D, Collins JF. (2019) Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis. Mol Ther (Mar), 27(3): 493-506.
Richard Gronostajski, PhD
- Chen KS, Lynton Z, Lim JWC, Robertson T, Gronostajski RM, Bunt J, Richards LJ. (2020) NFIA and NFIB function as tumour suppressors in high-grade glioma in mice. Carcinogenesis (Dec).
- Matuzelski E, Essebier A, Harris L, Gronostajski RM, Harvey TJ, Piper M. (2020) Alterations in gene expression in the spinal cord of mice lacking Nfix. BMC Res Notes (Sep), 13(1): 437-437.
- Qi L, Yin G, Zhang Y, Tao Y, Wu X, Gronostajski RM, Qiu M, Liu Y. (2020) Nuclear Factor I/A Controls A-fiber Nociceptor Development. Neurosci Bull (Jul), 36(7): 685-695.
Marc Halfon, PhD
- Schember I, Halfon MS. (2021) Identification of new Anopheles gambiae transcriptional enhancers using a cross-species prediction approach. Insect molecular biology (Apr).
- Nowling RJ, Behura SK, Halfon MS, Emrich SJ, Duman-Scheel M. (2021) PeakMatcher facilitates updated Aedes aegypti embryonic cis-regulatory element map. Hereditas (Jan), 158(1): 7. doi:10.1186/s41065-021-00172-2
- Sinha S, Jones BM, Traniello IM, Bukhari SA, Halfon MS, Hofmann HA, Huang S, Katz PS, Keagy J, Lynch VJ, Sokolowski MB, Stubbs LJ, Tabe-Bordbar S, Wolfner MF, Robinson GE. (2020) Behavior-related gene regulatory networks: A new level of organization in the brain. Proceedings of the National Academy of Sciences of the United States of America (Sep), 117(38): 23270-23279. doi:10.1073/pnas.1921625117
Daniel Kosman, PhD
- Dlouhy AC, Bailey DK, Steimle BL, Parker HV, Kosman DJ. (2019) Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux. J Biol Chem (Jan).
Techung Lee, PhD
- Lin H, Zhu L, Baker SS, Baker RD, Lee T. (2020) Secreted phosphoglucose isomerase is a novel biomarker of nonalcoholic fatty liver in mice and humans. Biochem Biophys Res Commun (Sep), 529(4): 1101-1105.
- Shabbir A, Suzuki G, Lee T. (2020) Influence of Organismal Aging in Mesenchymal Stem Cell Therapy. Am J Biomed Sci Res (Jun), 9(2): 105-106.
Norma Nowak, PhD
- Tsompana M, Gluck C, Sethi I, Joshi I, Bard J, Nowak NJ, Sinha S, Buck MJ, Buck M. (2020) Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma. Oncogene (Jan), 39(2): 262-277.
- Shen H, Yang N, Truskinovsky A, Chen Y, Mussell AL, Nowak NJ, Kobzik L, Frangou C, Zhang J. (2019) Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis. Mol Cancer Res (Jan), 17(1): 250-262.
Yungki Park, PhD
- Wang W, Cho H, Kim D, Park Y, Moon JH, Lim SJ, Yoon SM, McCane M, Aicher SA, Kim S, Emery B, Lee JW, Lee S, Park Y, Lee SK. (2020) PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. Cell Reports (Sep), 32(11): 108147.
- Jiang K, Kessler H, Park Y, Sudman M, Thompson SD, Jarvis JN. (2020) Broadening our understanding of the genetics of Juvenile Idiopathic Arthritis (JIA): Interrogation of three dimensional chromatin structures and genetic regulatory elements within JIA-associated risk loci. PLoS One (Jul), 15(7): e0235857.
- An H, Fan C, Sharif M, Kim D, Poitelon Y, Park Y. (2020) Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects. Scientific Reports (Jan), 10(1): 814.
Mulchand Patel, PhD
- Dumolt JH, Patel MS, Rideout TC. (2021) Excessive early-life cholesterol exposure may have later-life consequences for nonalcoholic fatty liver disease. Journal of developmental origins of health and disease (Apr), 12(2): 229-236. doi:10.1017/S2040174420000239
- Patel MS, Mahmood S, Jung J, Rideout TC. (2021) Reprogramming of aerobic glycolysis in non-transformed mouse liver with pyruvate dehydrogenase complex deficiency. Physiological reports (Jan), 9(1): e14684. doi:10.14814/phy2.14684
- Freedman D, Klejbor I, Mahmood S, Patel M, Stachowiak MK, Stachowiak EK. (2020) Loss of Oligodendrocytes in Mouse Model of Pyruvate Dehydrogenase Complex Deficiency and Partial Reversal by Phenylbutyrate Treatment.
Gabriela Popescu, PhD
- Iacobucci GJ, Wen H, Helou M, Liu B, Zheng W, Popescu GK. (2021) Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors. Proceedings of the National Academy of Sciences of the United States of America (Jan), 118(2). doi:10.1073/pnas.2007511118
- Popescu GK. (2020) FRET-ting over Inactivation. Biophysical journal (Dec), 119(11): 2139-2140. doi:10.1016/j.bpj.2020.10.015
- Abbott JA, Popescu GK. (2020) Hydroxynorketamine Blocks N-Methyl-d-Aspartate Receptor Currents by Binding to Closed Receptors. Molecular pharmacology (Sep), 98(3): 203-210. doi:10.1124/mol.120.119784
Christine Schaner Tooley, PhD
- Nevitt C, Tooley JG, Schaner Tooley CE, Schaner Tooley CE. (2018) N-terminal acetylation and methylation differentially affect the function of MYL9. Biochem J (Oct), 475(20): 3201-3219.
- Faughn JD, Dean WL, Schaner Tooley CE, Schaner Tooley CE. (2018) The N-terminal methyltransferase homologs NRMT1 and NRMT2 exhibit novel regulation of activity through heterotrimer formation. Protein Sci (Sep), 27(9): 1585-1599.
Satrajit Sinha, PhD
- Oyelakin A, Horeth E, Song EC, Min S, Che M, Marzullo B, Lessard CJ, Rasmussen A, Radfar L, Scofield RH, Lewis DM, Stone DU, Grundahl K, De Rossi SS, Kurago Z, Farris AD, Sivils KL, Sinha S, Kramer JM, Romano RA. (2021) Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjogren‘s Syndrome. Front Immunol (Jan), 11: 606268-606268.
- Oyelakin A, Horeth E, Song EC, Min S, Che M, Marzullo B, Lessard CJ, Rasmussen A, Radfar L, Scofield RH, Lewis DM, Stone DU, Grundahl K, De Rossi SS, Kurago Z, Farris AD, Sivils KL, Sinha S, Kramer JM, Romano RA, Romano R. (2021) Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren‘s Syndrome. Front Immunol (Jan), 11: 606268-606268.
- Min S, Oyelakin A, Gluck C, Bard JE, Song EC, Smalley K, Che M, Flores E, Sinha S, Romano RA, Romano R. (2020) p63 and Its Target Follistatin Maintain Salivary Gland Stem/Progenitor Cell Function through TGF-B/Activin Signaling. iScience (Sep), 23(9): 101524-101524.
Jennifer Surtees, PhD
- Surtees JA, Russo T, Burnidge, AH. (2020) Mutation and Migration: Understanding and interpreting the meaning in our genomes. Perspectives from Biochemistry, Genetics, Infectious Disease and Dance. Transforming Global Health: Interdisciplinary Challenges, Perspectives, and Strategies (Jan)213-228.
- Williams GM, Petrides AK, Balakrishnan L, Surtees JA. (2020) Tracking expansions of stable and threshold length trinucleotide repeat tracts in vivo and in vitro using Saccahromyces cerevisiae. Methods in Molecular Biology (Jan), 2056: 25-68.
- Subramaniam R, Lamb NA, Hwang Y, Johengen L, Surtees JA. (2019) Extracting and Measuring dNTP Pools in Saccharomyces cerevisiae. Methods Mol Biol (Jan), 1999: 103-127.
Mark Sutton, PhD
- Crane JK, Alvarado CL, Sutton MD. (2021) Role of the SOS Response in the Generation of Antibiotic Resistance In Vivo. Antimicrobial agents and chemotherapy (Jun), 65(7): e0001321.
- Almawi AW, Scotland MK, Randall JR, Liu L, Martin HK, Sacre L, Shen Y, Pillon MC, Simmons LA, Sutton MD, Guarné A. (2019) Binding of the regulatory domain of MutL to the sliding ß-clamp is species specific. Nucleic Acids Res (Mar).
- Crane JK Muhammad B. Cheema Michael A. Olyer Sutton MD. (2018) Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. Frontiers in Cellular and Infection Microbiology (Nov), 8(410): 1-12.
