Recent Faculty Publications

Anna Blumental-Perry

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Sarah Bowman, PhD

Aragon M, Bowman SEJ, Chen CH, Cruz MJ, Decato DA, Eng ET, Flatt KM, Gulati S, Li Y, Lomba CJ, Mercado B, Miller J, Palatinus L, Rice WJ, Waterman D, Zimanyi CM. (2024) Applying 3D ED/MicroED workflows toward the next frontiers. Acta crystallographica. Section C, Structural chemistry (Jun).
Lynch ML, Snell ME, Potter SA, Snell EH, Bowman SEJ. (2023) 20 years of crystal hits: progress and promise in ultrahigh-throughput crystallization screening. Acta crystallographica. Section D, Structural biology (Mar), 79(Pt 3): 198-205. doi:10.1107/S2059798323001274
Budziszewski GR, Snell ME, Wright TR, Lynch ML, Bowman SEJ. (2023) High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography. Journal of visualized experiments : JoVE (Mar)(193). doi:10.3791/65211

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Michael Buck, PhD

Maley SJ, Yue Y, Burns KF, Hovey KM, Wactawski-Wende J, Freudenheim JL, McSkimming DI, LaMonte MJ, Andrews CA, Sun Y, Buck M, Millen AE. (2023) Alcohol Consumption and the Diversity of the Oral Microbiome in Postmenopausal Women. The Journal of nutrition (Oct).
Oyelakin A, Sosa J, Nayak KB, Glathar A, Gluck C, Sethi I, Tsompana M, Nowak N, Buck M, Romano RA, Sinha S. (2023) An integrated genomic approach identifies follistatin as a target of the p63-epidermal growth factor receptor oncogenic network in head and neck squamous cell carcinoma. NAR cancer (Sep), 5(3): zcad038. doi:10.1093/narcan/zcad038
Ramalingam V, Yu X, Slaughter BD, Unruh JR, Brennan KJ, Onyshchenko A, Lange JJ, Natarajan M, Buck M, Zeitlinger J. (2023) Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development. Nature communications (Sep), 14(1): 5862. doi:10.1038/s41467-023-41408-1

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Rebekah Charney, PhD

Charney RM, Prasad MS, Juan-Sing C, Patel LJ, Hernandez JC, Wu J, García-Castro MI. (2023) Mowat-Wilson syndrome factor ZEB2 controls early formation of human neural crest through BMP signaling modulation. Stem cell reports (Nov), 18(11): 2254-2267.
Jansen C, Paraiso KD, Zhou JJ, Blitz IL, Fish MB, Charney RM, Cho JS, Yasuoka Y, Sudou N, Bright AR, Wlizla M, Veenstra GJC, Taira M, Zorn AM, Mortazavi A, Cho KWY. (2022) Uncovering the mesendoderm gene regulatory network through multi-omic data integration. Cell reports (Feb), 38(7): 110364. doi:10.1016/j.celrep.2022.110364

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Dahong Chen, PhD

Li Q, Chen D, Wang S. (2023) Character displacement of egg colors during tinamou speciation. Evolution; international journal of organic evolution (Jul), 77(8): 1874-1881.
Rosin LF, Chen D, Chen Y, Lei EP. (2022) Dosage compensation in Bombyx mori is achieved by partial repression of both Z chromosomes in males. Proceedings of the National Academy of Sciences of the United States of America (Mar), 119(10): e2113374119. doi:10.1073/pnas.2113374119

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D. Fernando Estrada, PhD

Alaina M Richard, D Fernando Estrada, Liam Flynn, Susan Sondej Pochapsky, Emily E Scott, Thomas C Pochapsky. (2024) Tracking protein-protein interactions by NMR: conformational selection in human steroidogenic cytochrome P450 CYP17A1 induced by cytochrome b5. Physical Chemistry Chemical Physics (Jun), 24(26): 16980-16988.
Christopher S Campomizzi, Patil Pranita Uttamrao, Jack J Stallone, Thenmalarchelvi Rathinavelan, D Fernando Estrada. (2024) Asparagine-85 Stabilizes a Structural Active Site Water Network in CYP121A1 of Mycobacterium tuberculosis. Biochemistry (Feb)(Online ahead of print) doi:10.1021/acs.biochem.3c00555
Jay N, McGlohon JE, Estrada DF. (2023) Interactions of human mitochondrial Ferredoxin 1 (Adrenodoxin) by NMR; modulation by cytochrome P450 substrate and by truncation of the C-terminal tail. Journal of Inorganic Biochemistry (Dec), 249: 112370. doi:10.1016/j.jinorgbio.2023.112370

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Lee Ann Garrett-Sinha, PhD

Kim N, Ju IG, Jeon SH, Lee Y, Jung MJ, Gee MS, Cho JS, Inn KS, Garrett-Sinha LA, Oh MS, Lee JK. (2023) Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer's disease mouse model. Journal of neuroinflammation (Nov), 20(1): 282. doi:10.1186/s12974-023-02966-9
Battaglia M, Garrett-Sinha LA. (2023) Staphylococcus xylosus and Staphylococcus aureus as commensals and pathogens on murine skin. Laboratory animal research (Aug), 39(1): 18. doi:10.1186/s42826-023-00169-0
Garrett-Sinha LA. (2023) An update on the roles of transcription factor Ets1 in autoimmune diseases. WIREs mechanisms of disease (Jan), 15(6): e1627.

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Marc Halfon, PhD

Dyer NA, Lucas ER, Nagi SC, McDermott D, Brenas JH, Miles A, Clarkson CS, Mawejje HD, Wilding CS, Halfon MS, Asma H, Heinz E, Donnelly MJ. (2023) Mechanisms of transcriptional regulation in Anopheles gambiae revealed by allele specific expression. bioRxiv : the preprint server for biology (Nov). doi:10.1101/2023.11.22.568226
Garza AB, Garcia R, Halfon MS, Girgis HZ. (2023) Evaluation of metric and representation learning approaches: Effects of representations driven by relative distance on the performance. 2023 Intelligent Methods, Systems, and Applications (Jul), 2023: 545-550. doi:10.1109/imsa58542.2023.10217475
Weinstein ML, Jaenke CM, Asma H, Spangler M, Kohnen KA, Konys CC, Williams ME, Williams AV, Rebeiz M, Halfon MS, Williams TM. (2023) A novel role for trithorax in the gene regulatory network for a rapidly evolving fruit fly pigmentation trait. PLoS genetics (Feb), 19(2): e1010653.

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Daniel Kosman, PhD

Pall AE, Bond S, Bailey DK, Stoj CS, Deschamps I, Huggins P, Parsons J, Bradbury MJ, Kosman DJ, Stemmler TL. (2024) ATH434, a promising iron-targeting compound for treating iron regulation disorders. Metallomics : integrated biometal science (Oct), 16(10).
Rosenblum SL, Bailey DK, Kosman DJ. (2024) Calcium and IL-6 regulate the anterograde trafficking and plasma membrane residence of the iron exporter ferroportin to modulate iron efflux. The Journal of biological chemistry (Jun), 300(6): 107348. doi:10.1016/j.jbc.2024.107348
Singha A, Sekretareva A, Tao L, Lim H, Ha Y, Braun A, Jones SM, Hedman B, Hodgson KO, Britt RD, Kosman DJ, Solomon EI. (2023) Tuning the Type 1 Reduction Potential of Multicopper Oxidases: Uncoupling the Effects of Electrostatics and H-Bonding to Histidine Ligands. Journal of the American Chemical Society (Jun), 145(24): 13284-13301. doi:10.1021/jacs.3c03241

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Techung Lee, PhD

Sabatini C, Ayenew L, Khan T, Hall R, Lee T. (2022) Dental Pulp Cell Conditioning through Polyinosinic-Polycytidylic Acid Activation of Toll-like Receptor 3 for Amplification of Trophic Factors. Journal of endodontics (Jul), 48(7): 872-879.

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Andrew Lombardo, Ph.D.

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Norma Nowak, PhD

Oyelakin A, Sosa J, Nayak KB, Glathar A, Gluck C, Sethi I, Tsompana M, Nowak N, Buck M, Romano RA, Sinha S. NAR Cancer. 2023 Jul 24;5(3):zcad038. doi: 10.1093/narcan/zcad038. PMID: 37492374; PMCID: PMC10365026. (2023) An integrated genomic approach identifies follistatin as a target of the p63-epidermal growth factor receptor oncogenic network in head and neck squamous cell carcinoma. Nucleic Acids Research Cancer (Sep), 5(3) doi:10.1093/narcan/zcad038

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Mark O‘Brian, PhD

Wu P, Ong A, O'Brian MR. (2024) Bradyrhizobium japonicum HmuP is an RNA-binding protein that positively controls hmuR operon expression by suppression of a negative regulatory RNA element in the 5' untranslated region. Molecular microbiology (May).
Ong A, O'Brian MR. (2024) Bradyrhizobium japonicum (diazoefficiens). Trends in microbiology (Apr).
Ong A, O'Brian MR. (2024) The Bradyrhizobium japonicum exporter ExsFGH is involved in efflux of ferric xenosiderophores from the periplasm. PloS one (Jan), 19(1): e0296306.

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Yungki Park, PhD

Lee JM, Jung H, Tang Q, Li L, Lee SK, Lee JW, Park Y, Kwon HE. (2024) KMT2D regulates tooth enamel development. bioRxiv : the preprint server for biology (Dec). doi:10.1101/2024.08.20.608898
Lee JM, Jung H, de Paula Machado Pasqua B, Park Y, Tang Q, Jeon S, Lee SK, Lee JW, Kwon HE. (2024) MLL4 regulates postnatal palate growth and midpalatal suture development. bioRxiv : the preprint server for biology (Nov). doi:10.1101/2024.07.16.603832
Jiang K, Liu T, Kales S, Tewhey R, Kim D, Park Y, Jarvis JN. (2024) A systematic strategy for identifying causal single nucleotide polymorphisms and their target genes on Juvenile arthritis risk haplotypes. BMC medical genomics (Jul), 17(1): 185. doi:10.1186/s12920-024-01954-z

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Mulchand Patel, PhD

Rideout TC, Andreani GA, Pembroke J, Choudhary D, Browne RW, Mahmood S, Patel MS. (2023) Maternal Pea Protein Intake Provides Sex-Specific Protection against Dyslipidemia in Offspring from Obese Pregnancies. Nutrients (Feb), 15(4). doi:10.3390/nu15040867
Dumolt JH, Patel MS, Rideout TC. (2022) Gestational hypercholesterolemia programs hepatic steatosis in a sex-specific manner in ApoE-deficient mice. The Journal of nutritional biochemistry (Mar), 101: 108945.

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Gabriela Popescu, PhD

Abbott JA, Wen H, Liu B, Gupta SS, Iacobucci GJ, Zheng W, Popescu GK. (2024) Allosteric inhibition of NMDA receptors by low dose ketamine. Molecular psychiatry (Sep)
Iacobucci GJ, Popescu GK. (2024) Calcium- and calmodulin-dependent inhibition of NMDA receptor currents. Biophysical journal (Feb), 123(3): 277-293. doi:10.1016/j.bpj.2023.12.018
Iacobucci GJ, Popescu GK. (2024) Estimating the Ca2+ Block of NMDA Receptors with Single-Channel Electrophysiology. Methods in molecular biology (Clifton, N.J.) (Jan), 2799: 151-175.

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Christine Schaner Tooley, PhD

Catlin JP, Schaner Tooley CE. (2024) Exploring potential developmental origins of common neurodegenerative disorders. Biochemical Society transactions (Apr).
Hobble HV, Schaner Tooley CE. (2024) Intrafamily heterooligomerization as an emerging mechanism of methyltransferase regulation. Epigenetics & chromatin (Mar), 17(1): 5. doi:10.1186/s13072-024-00530-0
Schaner Tooley CE. (2024) Reframing the relationship between motherhood and academic science. Trends in Biochemical Sciences (Jan), 1(49): 1-4. doi:10.1016/j.tibs.2023.08.008

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Satrajit Sinha, PhD

Oyelakin A, Sosa J, Nayak KB, Glathar A, Gluck C, Sethi I, Tsompana M, Nowak N, Buck M, Romano RA, Sinha S. (2023) An integrated genomic approach identifies follistatin as a target of the p63-epidermal growth factor receptor oncogenic network in head and neck squamous cell carcinoma. NAR cancer (Sep), 5(3): zcad038. doi:10.1093/narcan/zcad038
Song EC, Che M, Osinski J, Smalley K, Horeth E, Sinha S, Romano RA. (2023) ?Np63 maintains the fidelity of the myoepithelial cell lineage and directs cell differentiation programs in the murine salivary gland. Cell death and differentiation (Feb), 30(2): 515-526. doi:10.1038/s41418-022-01101-0
Glathar AR, Oyelakin A, Nayak KB, Sosa J, Romano RA, Sinha S. (2023) A Systemic and Integrated Analysis of p63-Driven Regulatory Networks in Mouse Oral Squamous Cell Carcinoma. Cancers (Jan), 15(2). doi:10.3390/cancers15020446

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Jennifer Surtees, PhD

Medina-Rivera M, Phelps S, Sridharan M, Becker J, Lamb NA, Kumar C, Sutton MD, Bielinsky A, Balakrishnan L, Surtees JA. (2023) Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivo. Nucleic acids research (Dec), 51(22): 12185-12206. doi:10.1093/nar/gkad934
Segelhurst E, Bard JE, Pillsbury AN, Alam MM, Lamb NA, Zhu C, Pohlman A, Boccolucci A, Emerson J, Marzullo BJ, Yergeau DA, Nowak NJ, Bradley IM, Surtees JA, Ye Y. (2023) Robust Performance of SARS-CoV-2 Whole-Genome Sequencing from Wastewater with a Nonselective Virus Concentration Method. ACS ES&T water (Apr), 3(4): 954-962. doi:10.1021/acsestwater.2c00456
Lamb NA, Bard JE, Loll-Krippleber R, Brown GW, Surtees JA. (2022) Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes. Genetics (Jul), 221(4). doi:10.1093/genetics/iyac092

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Mark Sutton, PhD

Medina-Rivera M, Phelps S, Sridharan M, Becker J, Lamb NA, Kumar C, Sutton MD, Bielinsky A, Balakrishnan L, Surtees JA. (2023) Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivo. Nucleic acids research (Dec), 51(22): 12185-12206. doi:10.1093/nar/gkad934
Scotland MK, Homiski C, Sutton MD. (2022) During Translesion Synthesis, Escherichia coli DinB89 (T120P) Alters Interactions of DinB (Pol IV) with Pol III Subunit Assemblies and SSB, but Not with the ß Clamp. Journal of bacteriology (Mar)e0061121.

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Mary Taub, Ph.D.

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Recent Faculty Publications

Anna Blumental-Perry

Sarah Bowman, PhD

Michael Buck, PhD

Rebekah Charney, PhD

Dahong Chen, PhD

D. Fernando Estrada, PhD

Lee Ann Garrett-Sinha, PhD

Marc Halfon, PhD

Daniel Kosman, PhD

Techung Lee, PhD

Andrew Lombardo, Ph.D.

Norma Nowak, PhD

Mark O‘Brian, PhD

Yungki Park, PhD

Mulchand Patel, PhD

Gabriela Popescu, PhD

Christine Schaner Tooley, PhD

Satrajit Sinha, PhD

Jennifer Surtees, PhD

Mark Sutton, PhD

Mary Taub, Ph.D.

Department of Biochemistry

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