Recent Faculty Publications
Bogdan Beirowski, MD, PhD
- Beirowski B, Beirowski BK. The LKB1-AMPK and mTORC1 Metabolic Signaling Networks in Schwann Cells Control Axon Integrity and Myelination: Assembling and upholding nerves by metabolic signaling in Schwann cells. Bioessays. 2019; 41(1)
- Wong KM, Beirowski B, Beirowski BK. Multiple lines of inhibitory feedback on AKT kinase in Schwann cells lacking TSC1/2 hint at distinct functions of mTORC1 and AKT in nerve development. Commun Integr Biol. 2018; 11(1)
Michael Buck, PhD
- Hu Z, Li H, Jiang H, Ren Y, Yu X, Qiu J, Stablewski AB, Zhang B, Buck MJ, Feng J, Buck M. Transient inhibition of mTOR in human pluripotent stem cells enables robust formation of mouse-human chimeric embryos. Sci Adv. 2020; 6(20)
- Yu X, Buck MJ, Buck M. Pioneer factors and their in vitro identification methods. Mol Genet Genomics. 2020
- Tsompana M, Gluck C, Sethi I, Joshi I, Bard J, Nowak NJ, Sinha S, Buck MJ, Buck M. Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma. Oncogene. 2020; 39(2)
D. Fernando Estrada, PhD
- Kumar A, Wilderman PR, Tu C, Shen S, Qu J, Estrada DF, Estrada D. Evidence of Allosteric Coupling between Substrate Binding and Adx Recognition in the Vitamin D Carbon-24 Hydroxylase CYP24A1. Biochemistry. 2020; 59(15)
- Kumar A, Estrada DF, Estrada D. Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate. Drug Metab Dispos. 2019; 47(9)
M. Laura Feltri, MD
- Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L, Feltri M. Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. Hum Mol Genet. 2019
- Florio F, Ferri C, Scapin C, Feltri ML, Wrabetz L, D‘Antonio M.. Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot-Marie-Tooth 1B Mouse Model. J Neurosci. 2018; 38(18)
- Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, Rush T, Vizzuso D, Court FA, Bachi A, Wrabetz L, Feltri ML, Feltri M. A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. J Neurochem. 2018; 145(3)
Lee Ann Garrett-Sinha, PhD
- Noviski M, Mueller JL, Satterthwaite A, Garrett-Sinha LA, Brombacher F, Zikherman J, Garrett-Sinha L. IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate. Elife. 2018; 7
Michael Garrick, PhD
- Wang X, Zhang M, Flores SRL, Woloshun RR, Yang C, Yin L, Xiang P, Xu X, Garrick MD, Vidyasagar S, Merlin D, Collins JF. Oral Gavage of Ginger Nanoparticle-Derived Lipid Vectors Carrying Dmt1 siRNA Blunts Iron Loading in Murine Hereditary Hemochromatosis. Mol Ther. 2019; 27(3)
Richard Gronostajski, PhD
- Oishi S, Harkins D, Kurniawan ND, Kasherman M, Harris L, Zalucki O, Gronostajski RM, Burne THJ, Piper M. Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome. EBioMedicine. 2019; 39
- Zalucki O, Harris L, Harvey TJ, Harkins D, Widagdo J, Oishi S, Matuzelski E, Yong XLH, Schmidt H, Anggono V, Burne THJ, Gronostajski RM, Piper M. NFIX-Mediated Inhibition of Neuroblast Branching Regulates Migration Within the Adult Mouse Ventricular-Subventricular Zone. Cereb Cortex. 2018
- Zalucki O, Harkins D, Harris L, Burne THJ, Gronostajski RM, Piper M. Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cells. BMC Res Notes. 2018; 11(1)
Marc Halfon, PhD
- Asma H, Halfon MS. Computational enhancer prediction: evaluation and improvements. BMC Bioinformatics. 2019; 20(1)
- Zhou Y, Popadowski SE, Deutschman E, Halfon MS. Correction: Distinct roles and requirements for Ras pathway signaling in visceral versus somatic muscle founder specification (doi:Â 10.1242/dev.169003). Development. 2019; 146(4)
- Halfon MS. Studying Transcriptional Enhancers: The Founder Fallacy, Validation Creep, and Other Biases. Trends Genet. 2019; 35(2)
Daniel Kosman, PhD
- Dlouhy AC, Bailey DK, Steimle BL, Parker HV, Kosman DJ. Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux. J Biol Chem. 2019
- Kosman DJ. For Cryptococcus neoformans, responding to the copper status in a colonization niche is not just about copper. Mol Microbiol. 2018; 108(5)
- Ji C, Steimle BL, Bailey DK, Kosman DJ. The Ferroxidase Hephaestin But Not Amyloid Precursor Protein is Required for Ferroportin-Supported Iron Efflux in Primary Hippocampal Neurons. Cell Mol Neurobiol. 2018; 38(4)
Techung Lee, PhD
- Lin H, Zhu L, Baker SS, Baker RD, Lee T. Secreted phosphoglucose isomerase is a novel biomarker of nonalcoholic fatty liver in mice and humans. Biochem Biophys Res Commun. 2020; 529(4)
- Shabbir A, Suzuki G, Lee T. Influence of Organismal Aging in Mesenchymal Stem Cell Therapy. Am J Biomed Sci Res. 2020; 9(2)
Norma Nowak, PhD
- Shen H, Yang N, Truskinovsky A, Chen Y, Mussell AL, Nowak NJ, Kobzik L, Frangou C, Zhang J. Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis. Mol Cancer Res. 2019; 17(1)
Gabriela Popescu, PhD
- Iacobucci GJ, Popescu GK. Kinetic models for activation and modulation of NMDA receptor subtypes. Curr Opin Physiol. 2018; 2
- Iacobucci GJ and Popescu GK. Kinetic Models for Activation and Modulation of NMDA Receptor Subtypes. Current Opinion in Physiology. 2018; 2
Christine Schaner Tooley, PhD
- Nevitt C, Tooley JG, Schaner Tooley CE, Schaner Tooley CE. N-terminal acetylation and methylation differentially affect the function of MYL9. Biochem J. 2018; 475(20)
- Faughn JD, Dean WL, Schaner Tooley CE, Schaner Tooley CE. The N-terminal methyltransferase homologs NRMT1 and NRMT2 exhibit novel regulation of activity through heterotrimer formation. Protein Sci. 2018; 27(9)
Satrajit Sinha, PhD
- Kumar S, Wilkes DW, Samuel N, Blanco MA, Nayak A, Alicea-Torres K, Gluck C, Sinha S, Gabrilovich D, Chakrabarti R. ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer. J Clin Invest. 2018; 128(11)
- Fan X, Wang D, Burgmaier JE, Teng Y, Romano R, Sinha S, Yi R. Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin. Dev Cell. 2018; 47(1)
Jennifer Surtees, PhD
- Williams GM, Petrides AK, Balakrishnan L, Surtees JA. Tracking expansions of stable and threshold length trinucleotide repeat tracts in vivo and in vitro using Saccahromyces cerevisiae. Methods in Molecular Biology. 2020; 2056
- Surtees JA, Russo T, Burnidge, AH. Mutation and Migration: Understanding and interpreting the meaning in our genomes. Perspectives from Biochemistry, Genetics, Infectious Disease and Dance.. Transforming Global Health: Interdisciplinary Challenges, Perspectives, and Strategies. 2020
- Subramaniam R, Lamb NA, Hwang Y, Johengen L, Surtees JA. Extracting and Measuring dNTP Pools in Saccharomyces cerevisiae. Methods Mol Biol. 2019; 1999
Mark Sutton, PhD
- Almawi AW, Scotland MK, Randall JR, Liu L, Martin HK, Sacre L, Shen Y, Pillon MC, Simmons LA, Sutton MD, Guarné A. Binding of the regulatory domain of MutL to the sliding ß-clamp is species specific. Nucleic Acids Res. 2019
- Crane JK Muhammad B. Cheema Michael A. Olyer Sutton MD. Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria. Frontiers in Cellular and Infection Microbiology. 2018; 8(410)
